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Dopamine is an essential hormone and a neurotransmitter involved in an array of processes and pathways. Disruption of any of the dopamine pathways can lead to diseases such as Parkinson's, Huntington's, schizophrenia, or anhedonia. The mesolimbic pathway of dopamine has a special association with the feeding behavior of a person, and disruption of this pathway has been shown to be associated with ED. In this article, we comprehensively assess the relation between dopamine and ED and discuss the clinical implications involving the pharmacological associations of drugs influencing dopamine levels and their impact on the treatment of ED.<\/jats:p>","DOI":"10.1111\/jne.70070","type":"journal-article","created":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T06:18:50Z","timestamp":1753337930000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Exploring the link between dopamine dysregulation and eating disorders: A narrative review"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6282-6698","authenticated-orcid":false,"given":"Zoaib Habib","family":"Tharwani","sequence":"first","affiliation":[{"name":"Dow Medical College Dow University of Health Sciences  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4089-0154","authenticated-orcid":false,"given":"Sean Kaisser","family":"Shaeen","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Dow University of Health Sciences  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-3616-3653","authenticated-orcid":false,"given":"Komal","family":"Zahid","sequence":"additional","affiliation":[{"name":"Department of Medicine Women Medical and Dental College  Abbotabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-4609-0652","authenticated-orcid":false,"given":"Shahzaib","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Dow International Medical College Dow University of Health Sciences  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rania","family":"Naqrashi","sequence":"additional","affiliation":[{"name":"Department of Medicine Frontier Medical and Dental College  Abbottabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Murtaza","sequence":"additional","affiliation":[{"name":"Department of Medicine Gomal Medical College  Dera Ismail Khan Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9794-9380","authenticated-orcid":false,"given":"Sanila","family":"Mughal","sequence":"additional","affiliation":[{"name":"Dow Medical College Dow University of Health Sciences  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9214-7840","authenticated-orcid":false,"given":"Muhammad","family":"Hasanain","sequence":"additional","affiliation":[{"name":"Dow Medical College Dow University of Health Sciences  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2429-515X","authenticated-orcid":false,"given":"Muhammad Umair","family":"Anjum","sequence":"additional","affiliation":[{"name":"Dow Medical College Dow University of Health Sciences  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2370-9368","authenticated-orcid":false,"given":"Mohammed Mahmmoud Fadelallah","family":"Eljack","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health Sciences University of Bakht Alruda  Ad Duwaym Sudan"},{"name":"Faculty of Medicine and Health Sciences, University of Bakht Alruda Kassala Teaching Hospital  Kassala Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syeda Wardah","family":"Zaidi","sequence":"additional","affiliation":[{"name":"Dow Medical College Dow University of Health Sciences  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,23]]},"reference":[{"key":"e_1_2_13_2_1","unstructured":"Psychiatry.org.What are eating disorders?Accessed December 1 2023.https:\/\/www.psychiatry.org\/patients-families\/eating-disorders\/what-are-eating-disorders"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/IJERPH20032446"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/AJCN\/NQY342"},{"key":"e_1_2_13_5_1","unstructured":"Binge eating disorder: symptoms causes and treatment. 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