{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T01:02:45Z","timestamp":1784854965992,"version":"3.55.0"},"reference-count":19,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:00:00Z","timestamp":1782950400000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Neuroendocrinology"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Small bowel neuroendocrine tumors (SBNET) are rare neoplasms that often present insidiously and may be associated with mesenteric fibrosis and advanced disease at diagnosis. While open surgery has traditionally been the standard of care, the role of laparoscopic resection in patients with complex SBNET remains under evaluation. We performed a retrospective analysis of all patients who underwent laparoscopic resection for SBNET at a tertiary referral center between 2002 and 2022. Clinical, operative, and oncologic data were extracted from a prospectively maintained database and reviewed for perioperative outcomes and long\u2010term survival. Forty patients (mean age 62.2\u2009years; 55% male) underwent laparoscopic resection, with a conversion rate of 7.5%. The ileum was the most common primary site (85%), and 75% of patients harbored a mesenteric mass. Postoperative morbidity was low (10%, all minor), with no perioperative mortality. The mean hospital stay was 7\u2009days. Most tumors were low\u2010grade (72.5% grade 1), yet 62.5% of patients presented with stage IV disease. With a mean follow\u2010up of 7\u2009years, overall survival reached 95\u2009months, and progression\u2010free survival 61\u2009months. Age at surgery was the only independent predictor of outcome. Laparoscopic resection of SBNET is feasible and safe in selected patients, including those with advanced disease and mesenteric involvement, providing favorable long\u2010term oncologic outcomes. These findings support the important role of minimally invasive surgery as part of the management of SBNET.<\/jats:p>","DOI":"10.1111\/jne.70224","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T09:36:12Z","timestamp":1782984972000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Laparoscopic resection of small bowel neuroendocrine tumors: A long\u2010term survival analysis"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2812-7551","authenticated-orcid":false,"given":"Michal","family":"Perets","sequence":"first","affiliation":[{"name":"Department of General Surgery Sha'are Zedek Medical Center, Faculty of Medicine, The Hebrew University of Jerusalem  Jerusalem Israel"},{"name":"Ellen Leifer Shulman and Steven Shulman Digestive Disease Center Cleveland Clinic Florida  Weston Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ofra","family":"Carmel","sequence":"additional","affiliation":[{"name":"Department of General Surgery Sha'are Zedek Medical Center, Faculty of Medicine, The Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anoushka","family":"Adler","sequence":"additional","affiliation":[{"name":"Department of General Surgery Sha'are Zedek Medical Center, Faculty of Medicine, The Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nir","family":"Horesh","sequence":"additional","affiliation":[{"name":"Ellen Leifer Shulman and Steven Shulman Digestive Disease Center Cleveland Clinic Florida  Weston Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Grozinsky\u2010Glasberg","sequence":"additional","affiliation":[{"name":"Neuroendocrine Tumor Unit, ENETS Center of Excellence, Endocrinology and Metabolism Department, Division of Medicine Hadassah\u2010Hebrew University Medical Center, and Faculty of Medicine, the Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petachia","family":"Reissman","sequence":"additional","affiliation":[{"name":"Department of General Surgery Sha'are Zedek Medical Center, Faculty of Medicine, The Hebrew University of Jerusalem  Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Freund","sequence":"additional","affiliation":[{"name":"Department of General Surgery Sha'are Zedek Medical Center, Faculty of Medicine, The Hebrew University of Jerusalem  Jerusalem 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