{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T02:27:35Z","timestamp":1772850455680,"version":"3.50.1"},"reference-count":46,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,6,17]],"date-time":"2013-06-17T00:00:00Z","timestamp":1371427200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neuropsychology"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:p>\n                    Limb apraxia is a neurological deficit characterized by an inability to pantomime and\/or imitate gestures, which can result from neurodegenerative disorders such as Alzheimer's disease (\n                    <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                    ). The major goal of the study was to describe comprehensively the apraxia deficits observed in\n                    <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                    patients and to relate those deficits to general cognitive status, measures of daily activity, and other neuropsychological measures. Limb apraxia was assessed on a variety of conceptual and gesture production tasks in 30\n                    <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                    patients. As a group,\n                    <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                    patients were impaired across gesture production tasks: of note was the greater impairment in imitation, as opposed to pantomime, which was especially pronounced when patients were imitating with a delay. Imitation performance was best predicted by measures of visuospatial processing, while imitation with delay was best predicted by measures of working memory. In addition, pantomime in response to pictures of tools was less accurate than Pantomime to Verbal Command and holding the tool during performance did not decrease the participants' impairment, while introducing a verbal cue during imitation increased the severity of deficits. Furthermore, investigation into patterns of deficits clearly demonstrated that the nature of limb apraxia deficits observed in\n                    <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                    can be quite heterogeneous and that dissociations between the conceptual and the production system exist. Finally, we also report on significant correlations between general cognitive status and limb apraxia.\n                  <\/jats:p>","DOI":"10.1111\/jnp.12023","type":"journal-article","created":{"date-parts":[[2013,6,17]],"date-time":"2013-06-17T04:23:43Z","timestamp":1371443023000},"page":"246-268","source":"Crossref","is-referenced-by-count":17,"title":["A model\u2010based approach to limb apraxia in Alzheimer's disease"],"prefix":"10.1111","volume":"8","author":[{"given":"Vessela","family":"Stamenova","sequence":"first","affiliation":[{"name":"Rotman Research Institute at Baycrest Toronto, Ontario, Canada"},{"name":"Heart and Stroke Foundation Centre for Stroke Recovery (HSFCSR) Baycrest, Toronto, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric A.","family":"Roy","sequence":"additional","affiliation":[{"name":"Department of Medicine Heart and Stroke Foundation Centre for Stroke Recovery (HSFCSR) Sunnybrook Health Sciences Centre University of Toronto Ontario, Canada"},{"name":"Department of Psychology\/Kinesiology University of Waterloo Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra E.","family":"Black","sequence":"additional","affiliation":[{"name":"Rotman Research Institute at Baycrest Toronto, Ontario, Canada"},{"name":"Department of Medicine Heart and Stroke Foundation Centre for Stroke Recovery (HSFCSR) Sunnybrook Health Sciences Centre University of Toronto Ontario, Canada"},{"name":"Department of Psychology\/Kinesiology University of Waterloo Ontario, Canada"},{"name":"Department of Medicine Division of Neurology University of Toronto Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,6,17]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2006.04.033"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.64.2.266"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0010-9452(13)80292-4"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.25.10.907"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468\u20101331.2001.00318.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/026432997381565"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bandc.2006.05.002"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0010\u20109452(08)70695\u20106"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1006\/brcg.2000.1226"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0028\u20103932(00)00081\u20106"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617700666079"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000107189"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1076\/jcen.21.4.488.887"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410190205"},{"key":"e_1_2_5_16_1","first-page":"161","article-title":"Ideomotor apraxia in Alzheimer disease and left hemisphere stroke: Limb transitive and intransitive movements","volume":"12","author":"Foundas A. 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