{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:23:41Z","timestamp":1777656221758,"version":"3.51.4"},"reference-count":57,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,2,23]],"date-time":"2015-02-23T00:00:00Z","timestamp":1424649600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neuropsychology"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:p>\n                    In this study, we have tested the effects of the dopamine D\n                    <jats:sub>2<\/jats:sub>\n                    receptor blocker pimozide on timing performance in patients with Tourette syndrome (\n                    <jats:styled-content style=\"fixed-case\">TS<\/jats:styled-content>\n                    ). Nine children with\n                    <jats:styled-content style=\"fixed-case\">TS<\/jats:styled-content>\n                    were tested off\u2010medication and following 3\u00a0months of daily treatment with pimozide. Subjects completed a time reproduction and a time production task using\n                    <jats:italic>supra<\/jats:italic>\n                    \u2010second temporal intervals. We show that pimozide improves motor timing performance by reducing the patients' variability in reproducing the duration of visual stimuli. On the other hand, this medication has no effect on the reproduction accuracy and on both variability and accuracy of the performance on the time production task.\u00a0Our results suggest that pimozide might have improved motor timing variability as a result of its beneficial side effect on endogenous dopamine levels (i.e., normalization).\n                  <\/jats:p>","DOI":"10.1111\/jnp.12064","type":"journal-article","created":{"date-parts":[[2015,2,23]],"date-time":"2015-02-23T06:26:10Z","timestamp":1424672770000},"page":"211-222","source":"Crossref","is-referenced-by-count":17,"title":["Timing recalibration in childhood Tourette syndrome associated with persistent pimozide treatment"],"prefix":"10.1111","volume":"10","author":[{"given":"Carmelo M.","family":"Vicario","sequence":"first","affiliation":[{"name":"School of Psychology Bangor University Wales UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariangela","family":"Gulisano","sequence":"additional","affiliation":[{"name":"Section of Child Neuropsychiatry Department of Medical and Pediatric Science Catania University Catania Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davide","family":"Martino","sequence":"additional","affiliation":[{"name":"Department of Neurology King's College Hospital NHS Foundation Trust London UK"},{"name":"Department of Neurology Queen Elizabeth Hospital, Lewisham &amp; 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