{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T22:25:04Z","timestamp":1792880704810,"version":"4.5.0"},"reference-count":47,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,4,29]],"date-time":"2017-04-29T00:00:00Z","timestamp":1493424000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["2011 MALZ 006 03"],"award-info":[{"award-number":["2011 MALZ 006 03"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neuropsychology"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:p>\n                    Recent works showed that tool use can be impaired in stroke patients because of either planning or technical reasoning deficits, but these two hypotheses have not yet been compared in the field of neurodegenerative diseases. The aim of this study was to address the relationships between real tool use, mechanical problem\u2010solving, and planning skills in patients with Alzheimer's disease (\n                    <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                    ,\n                    <jats:italic>n\u00a0<\/jats:italic>\n                    =\u00a032), semantic dementia (\n                    <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\n                    ,\n                    <jats:italic>n\u00a0<\/jats:italic>\n                    =\u00a016), and corticobasal syndrome (\n                    <jats:styled-content style=\"fixed-case\">CBS<\/jats:styled-content>\n                    ,\n                    <jats:italic>n\u00a0<\/jats:italic>\n                    =\u00a09). Patients were asked to select and use ten common tools, to solve three mechanical problems, and to complete the Tower of London test. Motor function and episodic memory were controlled using the Purdue Pegboard Test and the\n                    <jats:styled-content style=\"fixed-case\">BEC<\/jats:styled-content>\n                    96 questionnaire, respectively. A data\u2010transformation method was applied to avoid ceiling effects, and single\u2010case analysis was performed based on raw scores and completion time. All groups demonstrated either impaired or slowed tool use. Planning deficits were found only in the\n                    <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                    group. Mechanical problem\u2010solving deficits were observed only in the\n                    <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                    and\n                    <jats:styled-content style=\"fixed-case\">CBS<\/jats:styled-content>\n                    groups. Performance in the Tower of London test was the best predictor of tool use skills in the\n                    <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\n                    group, suggesting these patients had general rather than mechanical problem\u2010solving deficits. Episodic memory seemed to play little role in performance. Motor dysfunction tended to be associated with tool use skills in\n                    <jats:styled-content style=\"fixed-case\">CBS<\/jats:styled-content>\n                    patients, while tool use disorders are interpreted as a consequence of the semantic loss in\n                    <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\n                    in line with previous works. These findings may encourage caregivers to set up disease\u2010centred interventions.\n                  <\/jats:p>","DOI":"10.1111\/jnp.12121","type":"journal-article","created":{"date-parts":[[2017,4,29]],"date-time":"2017-04-29T03:06:04Z","timestamp":1493435164000},"page":"409-426","source":"Crossref","is-referenced-by-count":24,"title":["Tool use in neurodegenerative diseases: Planning or technical reasoning?"],"prefix":"10.1111","volume":"12","author":[{"given":"Josselin","family":"Baumard","sequence":"first","affiliation":[{"name":"Normandie Univ UNIROUEN CRFDP Rouen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Lesourd","sequence":"additional","affiliation":[{"name":"Laboratory for the Study of Cognitive Mechanisms (EA 3082) University of Lyon France"},{"name":"Neuropsychological Unit Neurological Hospital Pierre Wertheimer Bron France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chrystelle","family":"Remigereau","sequence":"additional","affiliation":[{"name":"Laboratory of Psychology LPPL (EA 4638) University of Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Jarry","sequence":"additional","affiliation":[{"name":"Laboratory of Psychology LPPL (EA 4638) University of Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9rique","family":"Etcharry\u2010Bouyx","sequence":"additional","affiliation":[{"name":"Laboratory of Psychology LPPL (EA 4638) University of Angers France"},{"name":"Department of Neurology University Hospital of Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Chauvir\u00e9","sequence":"additional","affiliation":[{"name":"Laboratory of Psychology LPPL (EA 4638) University of Angers France"},{"name":"Department of Neurology University Hospital of Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Osiurak","sequence":"additional","affiliation":[{"name":"Laboratory for the Study of Cognitive Mechanisms (EA 3082) University of Lyon France"},{"name":"French Universitary Institute Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Le Gall","sequence":"additional","affiliation":[{"name":"Laboratory of Psychology LPPL (EA 4638) University of Angers France"},{"name":"Neuropsychological Unit Department of Neurology University Hospital of Angers France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,4,29]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31827f0fd1"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-016-0675-0"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2016.06.007"},{"key":"e_1_2_6_5_1","first-page":"1","article-title":"The tool in the brain: Apraxia in ADL. 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