{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T23:13:44Z","timestamp":1792192424626,"version":"4.4.0"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,12,7]],"date-time":"2016-12-07T00:00:00Z","timestamp":1481068800000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Peripheral Nervous Sys"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Symptoms of Charcot\u2010Marie\u2010Tooth (CMT) disease typically arise in childhood or adolescence with gait difficulty most common. A systematic review was conducted to synthesise, review, and characterise gait in paediatric CMT. Health\u2010related electronic databases were reviewed with search terms related to CMT and gait. Of 454 articles, 10 articles describing seven studies met eligibility criteria; samples ranged from 1 to 81, included mixed CMT sub\u2010types and had a participant mean age of 13 years. Assessments included a variety of methods to examine only barefoot gait. Heterogeneity of gait patterns was noted. Children and adolescents with CMT walked slower, most likely due to shorter stride length. Common kinematic and kinetic abnormalities included significant foot drop during swing, reduced calf muscle power, and proximal compensatory mechanisms in the lower limb. Little data were found to inform typical functional gait characteristics or change over time. Of note, barefoot assessment does not reflect function in everyday life where footwear is commonly worn. With limited existing literature, future studies of gait in paediatric CMT need to evaluate the influence of diagnostic sub\u2010types and disease progression; the effect of factors such as footwear and the environment; and to explore changes in gait and function throughout childhood and adolescence.<\/jats:p>","DOI":"10.1111\/jns.12183","type":"journal-article","created":{"date-parts":[[2016,8,11]],"date-time":"2016-08-11T12:38:27Z","timestamp":1470919107000},"page":"317-328","source":"Crossref","is-referenced-by-count":22,"title":["Gait in children and adolescents with Charcot\u2010Marie\u2010Tooth disease: a systematic review"],"prefix":"10.1111","volume":"21","author":[{"given":"Rachel A.","family":"Kennedy","sequence":"first","affiliation":[{"name":"Department of Neurology The Royal Children's Hospital  Parkville VIC Australia"},{"name":"Murdoch Childrens Research Institute The Royal Children's Hospital  Parkville VIC Australia"},{"name":"Department of Physiotherapy, Melbourne 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