{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T14:17:15Z","timestamp":1761401835663},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,6,8]],"date-time":"2017-06-08T00:00:00Z","timestamp":1496880000000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Peripheral Nervous Sys"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In the early stage of disease, differentiating acute inflammatory demyelinating polyneuropathy (AIDP) and acute motor sensory axonal neuropathy (AMSAN) using only a conventional nerve conduction studies (NCS) may be difficult. We evaluated the differences in the motor axonal excitability properties of 16 cases of sensorimotor Guillain\u2010Barr\u00e9 syndrome by nerve excitability testing (NET). The antiganglioside antibody assay and follow\u2010up NCS resulted in 12 patients diagnosed as AIDP and 4 patients as AMSAN. Clinical and excitability parameters in each group were compared with those in 30 normal controls. Automated NET with threshold tracking techniques was used to calculate the strength\u2013duration time constant (SDTC), threshold electrotonus (TE), current\u2013threshold relationship (CTR), and recovery cycle (RC) of excitability. Except for subtle changes in excitability parameters, AIDP showed no definitive difference relative to normal controls. Comparison between AMSAN and normal controls also revealed no significant differences in the SDTC, TE, and CTR parameters. However, there were clear differences in some of the RC parameters: the relative refractory period was significantly longer in the AMSAN group than in the AIDP group (4.40 \u00b1 1.11 vs. 3.09 \u00b1 1.01 ms, mean \u00b1 SEM; p &lt; 0.001), while superexcitability was significantly less prominent in the AMSAN group (\u22126.80 \u00b1 10.30 vs. \u221226.48 \u00b1 1.17%, mean \u00b1 SEM; p &lt; 0.001). Our study identified that both AIDP and AMSAN were associated with subtle changes in excitability properties. Nonetheless, the prominent increase in refractoriness in AMSAN suggests the presence of a nodal conduction block.<\/jats:p>","DOI":"10.1111\/jns.12208","type":"journal-article","created":{"date-parts":[[2017,4,11]],"date-time":"2017-04-11T08:36:41Z","timestamp":1491899801000},"page":"85-91","source":"Crossref","is-referenced-by-count":7,"title":["Early discrimination of sensorimotor Guillain\u2010Barr\u00e9 syndrome into demyelinating or axonal subtype by automated nerve excitability testing"],"prefix":"10.1111","volume":"22","author":[{"given":"So Young","family":"Pyun","sequence":"first","affiliation":[{"name":"Department of Neurology National Police Hospital  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi\u2010Ri","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Neurology Busan Paik Hospital, Inje University College of Medicine  Busan Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ju Young","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kangdong Sacred Heart Hospital Hallym University College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim Jong","family":"Kuk","sequence":"additional","affiliation":[{"name":"Department of Neurology Dong\u2010A University College of Medicine  Busan Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seong\u2010Il","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Neurology Busan Paik Hospital, Inje University College of Medicine  Busan Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Seok","family":"Bae","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kangdong Sacred Heart Hospital Hallym University College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,6,8]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.12885"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(199802)21:2<137::AID-MUS1>3.0.CO;2-C"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410440512"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/118.3.597"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2014.10.2.94"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410350510"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410440210"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.10275"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.10488"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2006.01.018"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1142\/S0219635206001331"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2012.01.025"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2014-310097"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2010.208538"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8027.2007.00153.x"}],"container-title":["Journal of the Peripheral Nervous System"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjns.12208","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jns.12208","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T12:30:09Z","timestamp":1696249809000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jns.12208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["10.1111\/jns.12208"],"URL":"https:\/\/doi.org\/10.1111\/jns.12208","archive":["Portico"],"relation":{},"ISSN":["1085-9489","1529-8027"],"issn-type":[{"value":"1085-9489","type":"print"},{"value":"1529-8027","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6]]}}}