{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T06:48:29Z","timestamp":1783579709600,"version":"3.55.0"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,6,8]],"date-time":"2017-06-08T00:00:00Z","timestamp":1496880000000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004441","name":"Styrelsen f\u00f6r Internationellt Utvecklingssamarbete","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004441","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000278","name":"Department for International Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000278","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Peripheral Nervous Sys"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Although Guillain\u2010Barr\u00e9 syndrome (GBS) has higher incidence and poor outcome in Bangladesh, mortality from GBS in Bangladesh has never been explored before. We sought to explore the frequency, timing, and risk factors for deaths from GBS in Bangladesh. We conducted a prospective study on 407 GBS patients who were admitted to Dhaka Medical College Hospital, Dhaka, Bangladesh from 2010 to 2013. We compared deceased and alive patients to identify risk factors. Cox regression model was used to adjust for confounders. Of the 407 GBS patients, 50 (12%) died, with the median time interval between the onset of weakness and death of 18 days. Among the fatal cases, 24 (48%) were \u226540 years, 36 (72%) had a Medical Research Council sum score \u226420 at entry, 33 (66%) had a progressive phase &lt;8 days, and 27 (54%) required ventilation support. Ten patients (20%) died due to unavailability of ventilator. The strongest risk factor for deaths was lack of ventilator support when it was required (HR: 11.9; 95% confidence interval [CI]: 4.6\u201330.7). Other risk factors for death included age \u226540 years (HR: 5.9; 95% CI: 2.1\u201316.7), mechanical ventilation (HR: 2.3; 95% CI: 1.02\u20135.2), longer progressive phase (&gt;8 days) (HR: 2.06; 95% CI: 1.1\u20133.8), autonomic dysfunction (HR: 1.9; 95% CI: 1.05\u20133.6), and bulbar nerve involvement (HR: 5.4; 95% CI: 1.5\u201319.2). In Bangladesh, GBS is associated with higher mortality rates, which is related to lack of ventilator support, disease severity, longer progressive phase of the disease, autonomic dysfunction, and involvement of the bulbar nerves.<\/jats:p>","DOI":"10.1111\/jns.12215","type":"journal-article","created":{"date-parts":[[2017,4,27]],"date-time":"2017-04-27T04:33:07Z","timestamp":1493267587000},"page":"121-126","source":"Crossref","is-referenced-by-count":38,"title":["High mortality from Guillain\u2010Barr\u00e9 syndrome in Bangladesh"],"prefix":"10.1111","volume":"22","author":[{"given":"Tanveen","family":"Ishaque","sequence":"first","affiliation":[{"name":"Laboratory Sciences and Services Division International Centre for Diarrhoeal Disease Research, (icddr,b) Dhaka Bangladesh"},{"name":"Department of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad B.","family":"Islam","sequence":"additional","affiliation":[{"name":"Laboratory Sciences and Services Division International Centre for Diarrhoeal Disease Research, (icddr,b) Dhaka Bangladesh"},{"name":"Department of Medical Microbiology and Infectious Diseases Erasmus University Medical Centre Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gulshan","family":"Ara","sequence":"additional","affiliation":[{"name":"Laboratory Sciences and Services Division International Centre for Diarrhoeal Disease Research, (icddr,b) Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hubert P.","family":"Endtz","sequence":"additional","affiliation":[{"name":"Laboratory Sciences and Services Division International Centre for Diarrhoeal Disease Research, (icddr,b) Dhaka Bangladesh"},{"name":"Department of Medical Microbiology and Infectious Diseases Erasmus University Medical Centre Rotterdam The Netherlands"},{"name":"Fondation M\u00e9rieux Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quazi D.","family":"Mohammad","sequence":"additional","affiliation":[{"name":"National Institute of Neurosciences and Hospital Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart C.","family":"Jacobs","sequence":"additional","affiliation":[{"name":"Department of Neurology Erasmus University Medical Centre Rotterdam The Netherlands"},{"name":"Department of Immunology Erasmus University Medical Centre Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhahirul","family":"Islam","sequence":"additional","affiliation":[{"name":"Laboratory Sciences and Services Division International Centre for Diarrhoeal Disease Research, (icddr,b) Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,6,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"705","DOI":"10.33588\/rn.3508.2002352","article-title":"Guillain\u2010 Barr\u00e9 syndrome in the northern area of Gran Canaria and the island of Lanzarote","volume":"35","author":"Aladro\u2010Benito Y","year":"2002","journal-title":"Rev Neurol"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000310983.38724.d4"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410270707"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2007.08.005"},{"key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"4","DOI":"10.33588\/rn.5801.2013370","article-title":"Mortality associated with a diagnosis of Guillain\u2010Barr\u00e9 syndrome in adults of Mexican health institutions","volume":"58","author":"Dominguez\u2010Moreno 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