{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T15:54:53Z","timestamp":1793030093190,"version":"4.5.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,12,7]],"date-time":"2017-12-07T00:00:00Z","timestamp":1512604800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Peripheral Nervous Sys"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Intraneural perineurioma (IP) is an under\u2010recognized hypertrophic peripheral nerve tumor. It affects young patients involving frequently the sciatic nerve and its branches and presents with a progressive, painless and predominantly motor deficit. Magnetic resonance neurography (MRN) is a useful tool to localize the lesion, evaluate its extension, and discriminate between different etiologies. We reviewed the clinical records of 11 patients with pathologically confirm IP. Eight patients were males with mean age 19\u2009years. Initial complains were unilateral steppage (seven patients), bilateral steppage (one patient), unilateral gastrocnemius wasting (one patient), unilateral thigh atrophy (one patient), and unilateral hand weakness (one patient). Nine patients had mild painless sensory loss. Examinations revealed involvement of sciatic nerve extending into the peroneal nerve (eight patients), posterior tibial nerve (one patient), radial nerve (one patient), and femoral nerve (one patient). MRN revealed enlargement of the affected nerve isointense on T1\u2010weighted, hyperintense on T2 fat\u2010saturated images, and with avid enhancement on post\u2010contrast imaging. In all patients, a nerve biopsy confirmed the diagnosis. MRN allows early and non\u2010invasive identification of this tumor and is a key tool providing localization and differential diagnosis in patients with slowly progressive focal neuropathies.<\/jats:p>","DOI":"10.1111\/jns.12240","type":"journal-article","created":{"date-parts":[[2017,11,2]],"date-time":"2017-11-02T10:46:36Z","timestamp":1509619596000},"page":"23-28","source":"Crossref","is-referenced-by-count":13,"title":["Intraneural perineuriomas: diagnostic value of magnetic resonance neurography"],"prefix":"10.1111","volume":"23","author":[{"given":"Luciana","family":"Le\u00f3n Cejas","sequence":"first","affiliation":[{"name":"Department of Neurology Brit\u00e1nico Hospital  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Binaghi","sequence":"additional","affiliation":[{"name":"Department of Radiology Favaloro Foundation  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariano","family":"Socolovsky","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Brit\u00e1nico Hospital  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Dubrovsky","sequence":"additional","affiliation":[{"name":"Department of Neurology Favaloro Foundation  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Pirra","sequence":"additional","affiliation":[{"name":"Department of Neurology Favaloro Foundation  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cintia","family":"Marchesoni","sequence":"additional","affiliation":[{"name":"Department of Neurology Brit\u00e1nico Hospital  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Pardal","sequence":"additional","affiliation":[{"name":"Department of Neurology Brit\u00e1nico Hospital  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soledad","family":"Monges","sequence":"additional","affiliation":[{"name":"Department of Neurology Garrahan Hospital  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Peretti","sequence":"additional","affiliation":[{"name":"Department of Neurology Garrahan Hospital  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana L.","family":"Taratuto","sequence":"additional","affiliation":[{"name":"Garrahan Hospital Neuropathology Laboratory  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiana","family":"Lubinieki","sequence":"additional","affiliation":[{"name":"Garrahan Hospital Neuropathology Laboratory  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Reisin","sequence":"additional","affiliation":[{"name":"Department of Neurology Brit\u00e1nico Hospital  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,12,7]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2006.104.5.824"},{"key":"e_1_2_6_3_1","series-title":"American Registry of Pathology Editorial Atlas of tumor pathology","doi-asserted-by":"crossref","first-page":"266","DOI":"10.55418\/9781933477305","volume-title":"Tumors of the Peripheral Nervous System","author":"Antonescu CR","year":"2013"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198809000-00004"},{"key":"e_1_2_6_5_1","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.5858\/2007-131-1382-IPASRW","article-title":"Intraneural perineurioma. 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