{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T14:54:59Z","timestamp":1767192899118,"version":"3.40.5"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,1,16]],"date-time":"2019-01-16T00:00:00Z","timestamp":1547596800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Peripheral Nervous Sys"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:p>We aimed to elucidate characteristics of beriberi neuropathy (BB) in a general hospital (GH) setting. Nerve conduction studies (NCS), cross\u2010referenced with clinical records of patients admitted to a GH (May 2011\u2010July 2017), were reviewed for diagnosis of BB. Thirteen patients (age range 23\u201064 years; five women) were diagnosed with BB. Eleven were incarcerated (2\u201024 months) at time of index event. Eleven reported prior, severe anorexia (2\u20106 months); five reported significant weight loss, three had recurrent vomiting, and three reported alcohol misuse. Commonest presentation was weakness (12\/13); nine had symptom evolution over \u22653 weeks. At nadir, 11\/13 could not walk independently. Other features included numbness\/paraesthesiae (10\/13), dysautonomia (6\/13), vocal cord dysfunction\/dysphagia (4\/13), nystagmus (3\/13). Pain was not prominent. Cerebrospinal fluid, tested in five patients, was acellular; one showed mildly increased protein. NCS showed predominantly sensorimotor, axonal polyneuropathy, rarely asymmetric. Only one patient had sural\u2010sparing pattern. All received high dose thiamine. Two of the thirteen received intravenous immunoglobulin for suspicion of Guillain\u2010Barr\u00e9 syndrome (GBS). Eleven improved to independent ambulation. One patient died from pulmonary embolism; one was lost to follow\u2010up. Two of the thirteen had residual neurocognitive effects; both misused alcohol. Besides GBS, BB is an important cause of acute to subacute flaccid paralysis, especially in incarcerated patients and those with significant dietary deprivation. Features favoring BB over GBS are \u22653 weeks of symptoms, nystagmus, confusion, vocal cord dysfunction, volume overload, normal spinal fluid, elevated lactate, and absence of sural\u2010sparing pattern in NCS.<\/jats:p>","DOI":"10.1111\/jns.12297","type":"journal-article","created":{"date-parts":[[2018,12,20]],"date-time":"2018-12-20T02:49:26Z","timestamp":1545274166000},"page":"145-149","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Acute flaccid paralysis: Do not forget beriberi neuropathy"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9119-6250","authenticated-orcid":false,"given":"Monica","family":"Saini","sequence":"first","affiliation":[{"name":"Department of Medicine, Neurology Changi General Hospital  Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wee","family":"Lin","sequence":"additional","affiliation":[{"name":"Lee Kong Chian School of Medicine  Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corrine","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Medicine, Neurology Changi General Hospital  Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thirugnanam","family":"Umapathi","sequence":"additional","affiliation":[{"name":"Department of Neurology National Neuroscience Institute  Singapore 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