{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T03:09:05Z","timestamp":1792638545804,"version":"4.5.0"},"reference-count":38,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,8,5]],"date-time":"2020-08-05T00:00:00Z","timestamp":1596585600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Peripheral Nervous Sys"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Structural foot deformities consequent to Charcot Marie Tooth (CMT) can be treated by functional surgery (FS). This study aims to evaluate both long\u2010term walking ability and patients' satisfaction in CMT subjects who underwent FS during their lifetime. We conducted a retrospective observational study. Age, sex, CMT type, comprehensive surgical history, current walking ability assessed by the Walking Handicap Scale (WHS) and patients' global impression of change (pGIC) were retrieved from a custom database managed at our institution. WHS and pGIC were assessed between mid\u20102018 and mid\u20102019. Data from 79 patients were screened and 63 were included, 35W\u201028M, mean age 42 (15), with demyelinating (75%), axonal (20%), and other types (5%) of CMT, who underwent FS between 1967 and 2018. FS evolved significantly over the years from bone\u2010related procedures (e.g., arthrodesis) to both bone and soft tissues\u2010related procedures. The re\u2010intervention rate decreased from 70% before 2000 to 32% in the last decade. Complications arose in five cases. FS was mainly performed on adults (73%). WHS was \u2265 5 in three\u2010quarters of the sample (range 1\u20106) and was significantly affected by age groups in patients with demyelinating CMT (n=47, p&lt;0.01, non\u2010parametric ANOVA). Nearly 80% of patients were satisfied with FS (pGIC \u2265 4). In conclusion, CMT subjects who underwent FS surgery maintained a high gait efficiency in the long\u2010term period, with middle to high levels of satisfaction in the majority of the cases. This confirms the validity of FS in the management of acquired foot deformities in CMT patients.<\/jats:p>","DOI":"10.1111\/jns.12404","type":"journal-article","created":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T11:58:42Z","timestamp":1594727922000},"page":"297-302","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Long\u2010term walking ability and patient satisfaction after lower limb functional surgery in patients affected by Charcot\u2010Marie\u2010Tooth disease: A retrospective study"],"prefix":"10.1111","volume":"25","author":[{"given":"Irene","family":"Carantini","sequence":"first","affiliation":[{"name":"S.C. Riabilitazione Neuromotoria Presidio di Bozzolo Dipartimento di Neuroscienze  Mantova Italy"},{"name":"ACMT\u2010Rete per la malattia di Charcot\u2010Marie\u2010Tooth OdV Association  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Merlo","sequence":"additional","affiliation":[{"name":"MerloBioengineering  Parma Italy"},{"name":"Gait &amp; Motion Analysis Laboratory Sol et Salus Hospital  Rimini Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donatella","family":"Esposito","sequence":"additional","affiliation":[{"name":"ACMT\u2010Rete per la malattia di Charcot\u2010Marie\u2010Tooth OdV Association  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Zerbinati","sequence":"additional","affiliation":[{"name":"Gait &amp; Motion Analysis Laboratory Sol et Salus Hospital  Rimini Italy"},{"name":"U.O. 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