{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T03:55:23Z","timestamp":1774410923660,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T00:00:00Z","timestamp":1747699200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005202","name":"Muscular Dystrophy Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005202","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002721","name":"Charcot-Marie-Tooth Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002721","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Peripheral Nervous Sys"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>The CMT Infant Scale (CMTInfS) enables evaluation of infants\/toddlers in clinic. Our aim was to evaluate the feasibility, reliability, and validity of a virtual version of the CMTInfS (vCMTInfS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Children aged 55\u2009months or less were evaluated either in clinic using CMTInfS or remotely via telemedicine using the vCMTInfS. A trained clinical evaluator remotely directed activities with assistance from the parent\/caregiver. vCMTInfS scores were calculated using the CMTInfS calculator available at <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.clinicaloutcomemeasures.org\">www.ClinicalOutcomeMeasures.org<\/jats:ext-link>. Clinical evaluators also used the Brazelton Neonatal Behavior assessment scale to give insight into the behavior of the child during the exam.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty children (10 males and 10 females) aged 6\u201355\u2009months with confirmed or at risk for CMT were evaluated. The mean in person (IP) CMT Infant and Toddler Scale (CMTInfS) raw score (4.11, SD\u2009=\u20092.76) was not significantly different from the mean initial virtual (V1) CMTInfS raw score (3.78, SD\u2009=\u20092.59) using a two\u2010tailed test (<jats:italic>t<\/jats:italic>\u2009=\u20091.000, <jats:italic>p<\/jats:italic>\u2009=\u20090.347). Differences between the first and second (V2) visits as well as between the IP and V2 visits were also nonsignificant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>Our data demonstrate that children aged 55\u2009months or less can be effectively evaluated remotely using the vCMTInfS, which will expand the number of very young children who can be evaluated with rare forms of CMT.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jns.70029","type":"journal-article","created":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T11:44:13Z","timestamp":1747741453000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Feasibility, Validity, and Reliability of the Virtual <scp>CMT<\/scp> Infant Toddler Scale (<scp>vCMTInfS<\/scp>): A Remote Evaluation of Infants\/Toddlers With <scp>CMT<\/scp>"],"prefix":"10.1111","volume":"30","author":[{"given":"Rosemary","family":"Shy","sequence":"first","affiliation":[{"name":"Department of Neurology, Neuromuscular and Neurogenetics Division University of Iowa Health Care, Carver College of Medicine  Iowa City Iowa USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Dragon","sequence":"additional","affiliation":[{"name":"Department of Neurology, Neuromuscular and Neurogenetics Division University of Iowa Health Care, Carver College of Medicine  Iowa City Iowa USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shawna M. E.","family":"Feely","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurology, Seattle Children's Hospital University of Washington School of Medicine  Seattle Washington USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabrielle","family":"Donlevy","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health University of Sydney School of Health Sciences, The Children's Hospital Westmead  Westmead Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kayla","family":"Cornett","sequence":"additional","affiliation":[{"name":"Sydney Children's Hospitals Network and Discipline of Paediatrics and Child Health, School of Clinical Medicine University of New South Wales  Sydney NSW Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Mandarakas","sequence":"additional","affiliation":[{"name":"Sydney Children's Hospitals Network and Discipline of Paediatrics and Child Health, School of Clinical Medicine University of New South Wales  Sydney NSW Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Estilow","sequence":"additional","affiliation":[{"name":"Department of Occupational Therapy Children's Hospital of Philadelphia  Philadelphia Pennsylvania USA"},{"name":"Department of Neurology University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua","family":"Burns","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Cancer Control St. Jude Children's Research Hospital  Memphis Tennessee USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8460-6971","authenticated-orcid":false,"given":"Michael E.","family":"Shy","sequence":"additional","affiliation":[{"name":"Department of Neurology, Neuromuscular and Neurogenetics Division University of Iowa Health Care, Carver College of 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