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Ensuring measures such as the CMTPedS, CMTInfS and CMT\u2010FOM are easily accessible removes a barrier to implementation. The aims of this project were to: (1) design a web\u2010based platform to enable real\u2010time scoring of CMT outcome measures; (2) implement co\u2010designed training and quality assurance resources; and (3) establish a Global Certification Standard for clinical evaluators.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A consultation process informed the design of the web\u2010based platform and included a process evaluation of current users (<jats:italic>n<\/jats:italic>\u2009=\u200965). Training resources were co\u2010designed with key stakeholders (<jats:italic>n<\/jats:italic>\u2009=\u200951) including CMT physicians and scientists, clinical evaluators, pharmaceutical representatives, and patients through a mixed\u2010methods approach. A Global Certification Standard was developed through the co\u2010design process and Master Trainer expertise.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A web\u2010based platform, <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.clinicaloutcomemeasures.org\">www.ClinicalOutcomeMeasures.org<\/jats:ext-link> was designed and implemented in June 2020 as a freely available trial readiness resource for clinicians and researchers. The platform now has &gt;\u20091400 registered users from &gt;\u200945 countries. Clinical evaluators identified a lack of accessible training resources as the top barrier to accurate and reliable administration of CMT outcome measures. Video demonstrations, online workshops, and labelled photographs were ranked as the top training methods. Five guiding principles for the Global Certification Standard for CMT outcome measures were established.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>The web\u2010based platform provides real\u2010time scoring of CMT outcome measures, access to standardized training, and a Global Certification Standard to support accurate and reliable assessment of disease severity, progression, and treatment efficacy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jns.70062","type":"journal-article","created":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T02:55:14Z","timestamp":1758250514000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Designing and Implementing a Web\u2010Based Platform for Accurate and Reliable Clinical Outcome Measures and Global Certification for Evaluating Charcot\u2013Marie\u2013Tooth disease"],"prefix":"10.1111","volume":"30","author":[{"given":"Kayla M. D.","family":"Cornett","sequence":"first","affiliation":[{"name":"School of Health Sciences, Faculty of Medicine &amp; Health The University of Sydney  Sydney New South Wales Australia"},{"name":"Sydney Children's Hospitals Network  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Estilow","sequence":"additional","affiliation":[{"name":"Children's Hospital of Philadelphia  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Bray","sequence":"additional","affiliation":[{"name":"School of Health Sciences, Faculty of Medicine &amp; Health The University of Sydney  Sydney New South Wales Australia"},{"name":"Sydney Children's Hospitals Network  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa R.","family":"Mandarakas","sequence":"additional","affiliation":[{"name":"Sydney Children's Hospitals Network  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabrielle A.","family":"Donlevy","sequence":"additional","affiliation":[{"name":"School of Health Sciences, Faculty of Medicine &amp; Health The University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer N.","family":"Baldwin","sequence":"additional","affiliation":[{"name":"School of Health Sciences, Faculty of Medicine &amp; Health The University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Eichinger","sequence":"additional","affiliation":[{"name":"Univeristy of Rochester  Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard S.","family":"Finkel","sequence":"additional","affiliation":[{"name":"Center for Experimental Neurotherapeutics, St. Jude Children's Research Hospital  Memphis Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Burns","sequence":"additional","affiliation":[{"name":"St. Jude Disability Prevention Program, Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital  Memphis Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marnee J.","family":"McKay","sequence":"additional","affiliation":[{"name":"School of Health Sciences, Faculty of Medicine &amp; Health The University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.23572"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000207963"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awy280"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2016.0171"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.25009"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/JCP.0b013e3182776ebe"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3233\/JND-180301"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.jcp.0000219049.33008.b7"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.physio.2014.12.002"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000003466"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000003847"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2017.07.004"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.25966"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jns.12557"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jns.12538"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/jns.12084"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-019-1452-x"},{"key":"e_1_2_8_19_1","unstructured":"\u201cNIH Toolbox [online] \u201dhttps:\/\/nihtoolbox.org\/training\/."},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/21678421.2024.2320880"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jns.12619"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10545-016-9924-2"},{"key":"e_1_2_8_23_1","first-page":"19","article-title":"The Problem of Measurement Error in Multisite Clinical Trials","volume":"34","author":"Demitrack M. 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