{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T09:02:01Z","timestamp":1775638921133,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,11,16]],"date-time":"2025-11-16T00:00:00Z","timestamp":1763251200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,16]],"date-time":"2025-11-16T00:00:00Z","timestamp":1763251200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Peripheral Nervous Sys"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Charcot\u2013Marie\u2013Tooth disease (CMT) is a hereditary neuropathy that causes progressive muscle weakness, sensory deficits, and impaired mobility, significantly affecting quality of life (QoL). The Pediatric Charcot\u2013Marie\u2013Tooth Quality of Life (pCMT\u2010QoL) instrument was developed specifically for children with CMT. However, a validated Thai version is not yet available.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a cross\u2010sectional study at the Pediatric Neuromuscular Clinic from July 2023 to December 2024. Using a forward\u2013backward translation method, we adapted the pCMT\u2010QoL into Thai. Twenty\u2010three children with CMT and their caregivers completed the Thai questionnaire. We evaluated internal consistency using Cronbach's alpha and test\u2013retest reliability using intraclass correlation coefficients (ICCs). Convergent validity was examined via Pearson correlation between child self\u2010reports and parent\u2010proxy reports across functional, mental, and physical domains.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The Thai pCMT\u2010QoL demonstrated high test\u2013retest reliability (ICC &gt;\u20090.85) and satisfactory internal consistency (Cronbach's alpha &gt;\u20090.7) across most domains. Convergent validity was strong for the total and mental domains but weaker for the physical domain, reflecting differences in perception between children and parents. Parents generally reported higher QoL scores than children did, a finding consistent with studies in other neuromuscular diseases. Most participants completed the questionnaire within 15\u2009min, suggesting good feasibility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation<\/jats:title>\n                    <jats:p>The Thai pCMT\u2010QoL is a reliable, culturally adapted tool for assessing QoL in children with CMT. It is suitable for both remote and in\u2010clinic administration. Future studies with larger cohorts are needed to confirm its responsiveness to clinical changes and to broaden its application in diverse settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jns.70075","type":"journal-article","created":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T05:14:07Z","timestamp":1763356447000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Validation and Reliability of the Thai Pediatric Charcot\u2013Marie\u2013Tooth Quality of Life Outcome Measure"],"prefix":"10.1111","volume":"30","author":[{"given":"Pimchanok","family":"Kulsirichawaroj","sequence":"first","affiliation":[{"name":"Division of Neurology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"},{"name":"Center of Research Excellence for Neuromuscular Diseases, Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arisa","family":"Phochaisarn","sequence":"additional","affiliation":[{"name":"Division of Neurology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"},{"name":"Center of Research Excellence for Neuromuscular Diseases, Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sivaporn","family":"Limpaninlachat","sequence":"additional","affiliation":[{"name":"Faculty of Physical Therapy Mahidol University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nutchavadee","family":"Vorasan","sequence":"additional","affiliation":[{"name":"Genetic Epidemiology Research Cluster, Research Division, Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Surachai","family":"Likasitwattanakul","sequence":"additional","affiliation":[{"name":"Division of Neurology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5201-9200","authenticated-orcid":false,"given":"Sindhu","family":"Ramchandren","sequence":"additional","affiliation":[{"name":"Department of Neurology Wayne State University  Detroit Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael E.","family":"Shy","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Iowa Hospitals and Clinics  Iowa Iowa USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4557-0387","authenticated-orcid":false,"given":"Oranee","family":"Sanmaneechai","sequence":"additional","affiliation":[{"name":"Division of Neurology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"},{"name":"Center of Research Excellence for Neuromuscular Diseases, Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529\u20108027.2011.00324.x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2023.12.007"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2019.146625"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.23572"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awy280"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.25966"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jns.12494"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jns.12538"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jns.12615"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jns.12557"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.3233\/jnd\u2010230174"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ensci.2019.100200"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524\u20104733.2005.04054.x"},{"key":"e_1_2_10_15_1","article-title":"Cross\u2010Cultural 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