{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T19:19:51Z","timestamp":1790709591534,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:00:00Z","timestamp":1769126400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:00:00Z","timestamp":1769126400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Peripheral Nervous Sys"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Guillain\u2013Barr\u00e9 syndrome (GBS) is the leading cause of acute flaccid paralysis. A Chilean study for 2001\u20132012 reported an age\u2010standardized incidence of 2.10 per 100\u2009000. We updated nationwide GBS incidence for 2013\u20132022 by sex, age, and macrozone.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective, population\u2010based analysis of the Chilean Department of Statistics and Health Information (DEIS) hospital\u2010discharge database. Cases were identified with the ICD\u201010 code G61.0 and deduplicated. Incidence rates (IRs) per 100\u2009000, using official mid\u2010year populations, were age\u2010standardized to the World Health Organization standard and stratified by sex, 10\u2010year age groups, and five macrozones.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We identified 5096 discharges. The period crude IR was 2.73, and the age\u2010standardized IR was 2.60 per 100\u2009000. Annual standardized IRs ranged from 3.15 (2013) to 2.03 (2020). Men comprised 58.6% of cases; period IRs were 3.25 in males versus 2.34 in females. Age\u2010specific IRs rose from 2.47 at 0\u20139\u2009years to 5.76 at 70\u201379, then declined (3.63 at 80\u201389; 1.04 at \u2265\u200990). Regionally, IRs were lowest in the Far North (1.86) and North (2.26), intermediate in the Central zone (2.51), and highest in the South (4.55) and Far South (4.86).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation<\/jats:title>\n                    <jats:p>In 2013\u20132022, Chile's GBS incidence remained high by international standards and higher than in 2001\u20132012, with persistent male predominance, a peak among older adults, and a southward gradient. These updated background rates inform service planning, surveillance, and vaccine\u2010safety assessment, and support integrated epidemiologic\u2013microbiologic studies across macrozones.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jns.70103","type":"journal-article","created":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T07:11:56Z","timestamp":1769238716000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Incidence of Guillain\u2013Barr\u00e9 Syndrome in Chile: A Population\u2010Based Study Between 2013 and 2022"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9283-7757","authenticated-orcid":false,"given":"Ray\u00e9n","family":"Gali\u00e1\u2010Lla\u00f1a","sequence":"first","affiliation":[{"name":"Departamento de Kinesiolog\u00eda, Facultad de Medicina Universidad de Chile  Santiago 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Kinesiolog\u00eda, Facultad de Ciencias de la Salud Universidad Aut\u00f3noma de Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7974-4333","authenticated-orcid":false,"given":"Rodrigo","family":"Torres\u2010Castro","sequence":"additional","affiliation":[{"name":"Departamento de Kinesiolog\u00eda, Facultad de Medicina Universidad de Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4639-9574","authenticated-orcid":false,"given":"Roberto","family":"Vera\u2010Uribe","sequence":"additional","affiliation":[{"name":"Departamento de Kinesiolog\u00eda, Facultad de Medicina Universidad de Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4938-7018","authenticated-orcid":false,"given":"Guilherme","family":"Fregonezi","sequence":"additional","affiliation":[{"name":"PneumoCardioVascular Lab\/HUOL, Departamento de Fisioterapia, Hospital Universit\u00e1rio Onofre Lopes Universidade Federal do Rio Grande do Norte  Natal Rio Grande do Norte Brazil"},{"name":"Laborat\u00f3rio de Inova\u00e7\u00e3o Tecnol\u00f3gica em Reabilita\u00e7\u00e3o, Departamento de Fisioterapia, Universidade Federal do Rio Grande do Norte  Natal Rio Grande do Norte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8157-4086","authenticated-orcid":false,"given":"Gonzalo","family":"Rivera\u2010Lillo","sequence":"additional","affiliation":[{"name":"Departamento de Kinesiolog\u00eda, Facultad de Medicina Universidad de Chile  Santiago Chile"},{"name":"Departamento de Neurociencia, Facultad de Medicina Universidad de Chile  Santiago 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