{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T03:49:07Z","timestamp":1782186547093,"version":"3.54.5"},"reference-count":45,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Peripheral Nervous Sys"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Diabetic peripheral neuropathy (DPN) and neuropathic pain are associated with various psychosocial factors, but the effect of diabetes distress remains underexplored. This study examines the associations between diabetes distress, DPN, and neuropathic pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional analysis on participants with type 2 diabetes from The Maastricht Study was conducted. Diabetes distress was assessed with the PAID\u201020 questionnaire and categorized as low (score\u2009&lt;\u200916), moderate (score 17\u201339), and high (score\u2009\u2265\u200940). Neuropathic pain was measured with the DN4 questionnaire, while DPN was clinically assessed through vibration perception threshold. Logistic regression analyses on the outcomes DPN only, neuropathic pain, and both DPN and pain were conducted, adjusted for sociodemographic (age, sex, education) and clinical characteristics (insulin use, HbA1c, depression).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>1418 participants were included (median age: 64\u2009years, 68.4% male). Moderate and high diabetes distress were observed in 22.5% and 4.8% of participants. Moderate (adjusted OR: 1.95; 95% CI: 1.37\u20132.75) and high distress (adjusted OR: 3.64; 95% CI: 1.97\u20136.63) were associated with the presence of neuropathic pain, but not with DPN alone.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation<\/jats:title>\n                    <jats:p>Diabetes distress is strongly associated with neuropathic pain but not with DPN. These findings suggest that individuals with neuropathic pain may benefit from psychosocial screening and support.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jns.70130","type":"journal-article","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T23:49:54Z","timestamp":1779407394000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Associations Between Diabetes Distress, Diabetic Peripheral Neuropathy and Neuropathic Pain in People With Type 2 Diabetes\u2014The Maastricht Study"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-2361-364X","authenticated-orcid":false,"given":"Alice","family":"Cardon","sequence":"first","affiliation":[{"name":"Department of Prevention, Health Promotion and Community Care Copenhagen University Hospital \u2013 Steno Diabetes Center Copenhagen  Herlev Denmark"},{"name":"Department of Clinical Medicine Faculty of Health and Medical Sciences, University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryan","family":"Cleal","sequence":"additional","affiliation":[{"name":"Department of Prevention, Health Promotion and Community Care Copenhagen University Hospital \u2013 Steno Diabetes Center Copenhagen  Herlev Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mette","family":"Due\u2010Christensen","sequence":"additional","affiliation":[{"name":"Department of Prevention, Health Promotion and Community Care Copenhagen University Hospital \u2013 Steno Diabetes Center Copenhagen  Herlev Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Dukers\u2010Muijrers","sequence":"additional","affiliation":[{"name":"Care and Public Health Research Institute (CAPHRI), Maastricht University  Maastricht the Netherlands"},{"name":"Living Lab Public Health Mosa (AWPG), Public Health Service South Limburg  Heerlen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3248-8448","authenticated-orcid":false,"given":"Klaus","family":"Kirketerp\u2010M\u00f8ller","sequence":"additional","affiliation":[{"name":"Copenhagen Wound Healing Center, Bispebjerg University Hospital  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Rasmussen","sequence":"additional","affiliation":[{"name":"Department of Diabetes Care Copenhagen University Hospital \u2013 Steno Diabetes Center Copenhagen  Herlev Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarunveer S.","family":"Ahluwalia","sequence":"additional","affiliation":[{"name":"Department of Clinical and Translational Research Copenhagen University Hospital \u2013 Steno Diabetes Center Copenhagen  Herlev Denmark"},{"name":"The Bioinformatics Center, Department of Biology University of Copenhagen  Copenhagen Denmark"},{"name":"Joslin\u2010Beth Israel Deaconess Foot Center Beth Israel Deaconess Medical Center, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian Stevns","family":"Hansen","sequence":"additional","affiliation":[{"name":"Department of Translational Type 2 Diabetes Research Copenhagen University Hospital \u2013 Steno Diabetes Center Copenhagen  Herlev Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miranda T.","family":"Schram","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine CARIM, Cardiovascular Research Institute Maastricht, Maastricht University, MheNS, School for Mental Health and Neuroscience, Maastricht University  Maastricht the Netherlands"},{"name":"Heart and Vascular Center, Maastricht University Medical Center+  Maastricht the Netherlands"},{"name":"Department of Epidemiology Erasmus University Medical Center  Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annemarie","family":"Koster","sequence":"additional","affiliation":[{"name":"Care and Public Health Research Institute (CAPHRI), Maastricht University  Maastricht the Netherlands"},{"name":"Department of Social Medicine Maastricht University  Maastricht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,21]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474\u20104422(22)00188\u20100"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.2337\/db2022-01"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00400697"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.2337\/db20182\u20101"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.7326\/M20\u20101340"},{"key":"e_1_2_9_7_1","unstructured":"Terminology | International Association for the Study of 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