{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T10:03:40Z","timestamp":1790071420253,"version":"4.0.1"},"reference-count":239,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T00:00:00Z","timestamp":1784937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T00:00:00Z","timestamp":1784937600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT 173522"],"award-info":[{"award-number":["PJT 173522"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT 166199"],"award-info":[{"award-number":["PJT 166199"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009003","name":"Hotchkiss Brain Institute, University of Calgary","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009003","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012866","name":"Cumming School of Medicine, University of Calgary","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012866","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Peripheral Nervous Sys"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The peripheral nervous system (PNS) is responsible for innervating all regions of the body outside of the central nervous system (CNS), the latter consisting of the brain, spinal cord, and optic nerves. While myelin is an essential component for the efficient functioning of both CNS and peripheral nerve cells, it is particularly important for PNS neurons since their cell bodies lie at considerable distances from their innervated targets. As such, regulation of myelin content and formation in the PNS is a carefully controlled process that involves many cellular and molecular players. The peripheral nerve is a multicellular environment containing several non\u2010neuronal cell types such as fibroblasts, endothelial cells, pericytes, resident macrophages, and nonmyelinating and myelinating Schwann cells, all of which contribute to PNS homeostasis. This review focuses on the contributions of Schwann cells and macrophages and their molecular mediators in the formation, maintenance, degradation, and reformation of peripheral myelin during homeostasis of, and after damage to the PNS.<\/jats:p>","DOI":"10.1111\/jns.70148","type":"journal-article","created":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T10:26:07Z","timestamp":1784975167000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Molecular Mediators Associated With Myelination, Demyelination, and Remyelination in the Peripheral Nervous System"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0470-4254","authenticated-orcid":false,"given":"Kathleen Margaret","family":"Hagen","sequence":"first","affiliation":[{"name":"Department of Clinical Neurosciences Hotchkiss Brain Institute, University of Calgary  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2055-0574","authenticated-orcid":false,"given":"Shalina Sheryl","family":"Ousman","sequence":"additional","affiliation":[{"name":"Departments of Clinical Neurosciences, and Cell Biology and Anatomy Hotchkiss Brain Institute, University of Calgary  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,25]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3171\/2014.2.JNS131667"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/88.4.841"},{"issue":"1","key":"e_1_2_8_4_1","first-page":"35","article-title":"The Connective Tissue of Peripheral Nerve: An Electron Microscope Study","volume":"97","author":"Thomas P. K.","year":"1963","journal-title":"Journal of Anatomy"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.4161\/tisb.24956"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2007.08.003"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022\u20102275(20)38877\u20105"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471\u20104159.1967.tb09532.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022\u20102275(20)37002\u20104"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006\u20108993(75)90895\u20101"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471\u20104159.1973.tb00089.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410090710"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471\u20104159.2002.00987.x"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896\u20106273(00)80360\u20108"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.15\u201012\u201008281.1995"},{"issue":"3","key":"e_1_2_8_16_1","first-page":"483","article-title":"Molecular Anatomy and Genetics of Myelin Proteins in the Peripheral Nervous System","volume":"186","author":"Snipes G. J.","year":"1995","journal-title":"Journal of Anatomy"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301\u20100082(99)00049\u20100"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1022497114813"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms222111358"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.46.3.505"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn1426"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0686\u201009.2009"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a020487"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1746"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529\u20108027.2008.00168.x"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/0896\u20106273(95)90147\u20107"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.148.5.1035"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0896\u20106273(00)80873\u20109"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2006.05.007"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471\u20104159.1999.0730096.x"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.19\u201010\u201003847.1999"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.9.5233"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1177\/1073858415572361"},{"key":"e_1_2_8_34_1","first-page":"329","volume-title":"Peripheral Neuropathy","author":"Webster H. d. F.","year":"1984"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20761"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/342430a0"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2022.104132"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.900600305"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749\u20106632.1990.tb17937.x"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20750"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2017.10.003"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0884\u201011.2011"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn1139"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01175570"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2005.08.017"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1006\/mcne.1996.0052"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.273.5274.507"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.18\u201019\u201007891.1998"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.10.14.1751"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.258203"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2004.08.001"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/371796a0"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1006\/mcne.2000.0957"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.embor.7400573"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0029(19980601)41:5<372::AID-JEMT4>3.0.CO;2-S"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10020-023-00667-w"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.122.9.2847"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102199\u20108\u2010117"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.251543398"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4321"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12264\u2010022\u201000850\u20109"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01668507"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749\u20106632.1986.tb48077.x"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ne.09.030186.001513"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.12.3850"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006\u20108993(74)90498\u20103"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.28.9_part_2.59"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.78.3.943"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014\u20104827(88)90318\u20107"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.09\u201002\u201000625.1989"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.105.2.1023"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200411158"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.23\u201013\u201005520.2003"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4316"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200109021"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3179\u201013.2013"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.2001408"},{"key":"e_1_2_8_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1078"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1076595"},{"key":"e_1_2_8_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166\u20102236(03)00099\u20107"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0925\u20104773(96)00623\u20105"},{"key":"e_1_2_8_82_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1095862"},{"key":"e_1_2_8_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2006.08.008"},{"key":"e_1_2_8_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014\u20104886(03)00101\u20108"},{"key":"e_1_2_8_85_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12031\u2010007\u20109011\u20100"},{"key":"e_1_2_8_86_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1166562"},{"key":"e_1_2_8_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2011.11.006"},{"key":"e_1_2_8_88_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn1797"},{"key":"e_1_2_8_89_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1132341"},{"key":"e_1_2_8_90_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2849"},{"key":"e_1_2_8_91_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3857"},{"key":"e_1_2_8_92_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201307057"},{"key":"e_1_2_8_93_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1187735"},{"key":"e_1_2_8_94_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4814\u201011.2012"},{"key":"e_1_2_8_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2014.09.001"},{"key":"e_1_2_8_96_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1809\u201013.2013"},{"key":"e_1_2_8_97_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.062224"},{"key":"e_1_2_8_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022\u20102275(20)40117\u20108"},{"key":"e_1_2_8_99_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201706010"},{"key":"e_1_2_8_100_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471\u20104159.1998.71020549.x"},{"key":"e_1_2_8_101_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742\u20104658.2008.06808.x"},{"key":"e_1_2_8_102_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1116203"},{"key":"e_1_2_8_103_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0905633106"},{"key":"e_1_2_8_104_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41580\u2010019\u20100190\u20107"},{"key":"e_1_2_8_105_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.162488899"},{"key":"e_1_2_8_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092\u20108674(02)00872\u20103"},{"key":"e_1_2_8_107_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471\u20104159.2005.03056.x"},{"key":"e_1_2_8_108_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M701878200"},{"key":"e_1_2_8_109_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.310490.117"},{"key":"e_1_2_8_110_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1805538115"},{"key":"e_1_2_8_111_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2004.03.008"},{"key":"e_1_2_8_112_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41583\u2010020\u20100269\u20103"},{"key":"e_1_2_8_113_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.15\u201010\u201006445.1995"},{"key":"e_1_2_8_114_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471\u20104159.1983.tb08072.x"},{"key":"e_1_2_8_115_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2013.03.009"},{"key":"e_1_2_8_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006\u20108993(74)90002\u2010X"},{"key":"e_1_2_8_117_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102202\u20106\u20106"},{"key":"e_1_2_8_118_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471\u20104159.1990.tb01225.x"},{"key":"e_1_2_8_119_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749\u20106632.1965.tb20189.x"},{"key":"e_1_2_8_120_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00691149"},{"key":"e_1_2_8_121_1","doi-asserted-by":"publisher","DOI":"10.1007\/bf00691150"},{"key":"e_1_2_8_122_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4537\u201010.2011"},{"key":"e_1_2_8_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2019.05.060"},{"key":"e_1_2_8_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1044\u20107431(03)00241\u20100"},{"key":"e_1_2_8_125_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.9.3.769"},{"key":"e_1_2_8_126_1","doi-asserted-by":"publisher","DOI":"10.1113\/JP270874"},{"key":"e_1_2_8_127_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01188405"},{"key":"e_1_2_8_128_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1453\u201017.2017"},{"key":"e_1_2_8_129_1","doi-asserted-by":"publisher","DOI":"10.1186\/1742\u20102094\u20108\u2010110"},{"key":"e_1_2_8_130_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20766"},{"key":"e_1_2_8_131_1","doi-asserted-by":"publisher","DOI":"10.1186\/1742\u20102094\u20108\u2010109"},{"key":"e_1_2_8_132_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201503019"},{"key":"e_1_2_8_133_1","doi-asserted-by":"publisher","DOI":"10.1002\/jemt.10108"},{"key":"e_1_2_8_134_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750\u20103639.1999.tb00229.x"},{"key":"e_1_2_8_135_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2012.06.021"},{"key":"e_1_2_8_136_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4547(19960301)43:5<511::AID-JNR1>3.0.CO;2-L"},{"key":"e_1_2_8_137_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2533\u201021.2022"},{"key":"e_1_2_8_138_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7600309"},{"key":"e_1_2_8_139_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.11.031"},{"key":"e_1_2_8_140_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5812\u201011.2012"},{"key":"e_1_2_8_141_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2323"},{"key":"e_1_2_8_142_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42003\u2010020\u201001444\u20109"},{"key":"e_1_2_8_143_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.21041"},{"key":"e_1_2_8_144_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2006.09.108"},{"key":"e_1_2_8_145_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3027\u201007.2007"},{"key":"e_1_2_8_146_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.16274"},{"key":"e_1_2_8_147_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.40919"},{"key":"e_1_2_8_148_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1710566114"},{"key":"e_1_2_8_149_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.22957"},{"key":"e_1_2_8_150_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469\u20107580.1998.19240529.x"},{"key":"e_1_2_8_151_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401\u2010001\u20100504\u20106"},{"key":"e_1_2_8_152_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-1136(199708)20:4<333::AID-GLIA6>3.0.CO;2-6"},{"key":"e_1_2_8_153_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0266\u20107681(98)80006\u20105"},{"key":"e_1_2_8_154_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-1136(199706)20:2<87::AID-GLIA1>3.0.CO;2-1"},{"key":"e_1_2_8_155_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401\u2010015\u20101482\u20104"},{"key":"e_1_2_8_156_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978\u20100\u201012\u2010410499\u20100.00007\u20101"},{"key":"e_1_2_8_157_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.lab.0000056993.28149.bf"},{"key":"e_1_2_8_158_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0074\u20107742(09)87026\u20108"},{"key":"e_1_2_8_159_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2016.07.010"},{"key":"e_1_2_8_160_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1529\u20108027.2000.00026.x"},{"key":"e_1_2_8_161_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.18\u201017\u201006713.1998"},{"key":"e_1_2_8_162_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh407"},{"key":"e_1_2_8_163_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20200471"},{"key":"e_1_2_8_164_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002\u20109440(10)63070\u20102"},{"key":"e_1_2_8_165_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41593\u2010020\u20100618\u20106"},{"key":"e_1_2_8_166_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.22\u201008\u201003052.2002"},{"key":"e_1_2_8_167_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460\u20109568.2001.01425.x"},{"key":"e_1_2_8_168_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0165\u20105728(00)00343\u2010x"},{"key":"e_1_2_8_169_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2019.05.009"},{"key":"e_1_2_8_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2018.12.001"},{"key":"e_1_2_8_171_1","doi-asserted-by":"publisher","DOI":"10.4103\/1673\u20105374.324845"},{"key":"e_1_2_8_172_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3257\u201009.2009"},{"key":"e_1_2_8_173_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005072\u2010198903000\u201000002"},{"key":"e_1_2_8_174_1","doi-asserted-by":"publisher","DOI":"10.1186\/1742\u20102094\u20109\u2010176"},{"key":"e_1_2_8_175_1","doi-asserted-by":"publisher","DOI":"10.1007\/bf02150231"},{"key":"e_1_2_8_176_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.14\u201005\u201003231.1994"},{"key":"e_1_2_8_177_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.133.1.159"},{"key":"e_1_2_8_178_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460\u20109568.1998.00277.x"},{"key":"e_1_2_8_179_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2119\u201015.2015"},{"key":"e_1_2_8_180_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13578\u2010021\u201000725\u2010y"},{"key":"e_1_2_8_181_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035\u2010021\u201002607\u20103"},{"key":"e_1_2_8_182_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.21\u201010\u201003401.2001"},{"key":"e_1_2_8_183_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2007.02.009"},{"key":"e_1_2_8_184_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460\u20109568.1997.tb01694.x"},{"key":"e_1_2_8_185_1","doi-asserted-by":"publisher","DOI":"10.1006\/exnr.2000.7495"},{"key":"e_1_2_8_186_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460\u20109568.2003.02711.x"},{"key":"e_1_2_8_187_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00318572"},{"key":"e_1_2_8_188_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00307696"},{"key":"e_1_2_8_189_1","doi-asserted-by":"publisher","DOI":"10.1006\/nbdi.2001.0383"},{"key":"e_1_2_8_190_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1007012916530"},{"key":"e_1_2_8_191_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022\u2010510X(91)90162\u2010Z"},{"key":"e_1_2_8_192_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165\u20105728(89)90035\u20100"},{"key":"e_1_2_8_193_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1001948107"},{"key":"e_1_2_8_194_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006\u20108993(88)90756\u20101"},{"key":"e_1_2_8_195_1","doi-asserted-by":"publisher","DOI":"10.1186\/1742\u20102094\u20108\u201024"},{"key":"e_1_2_8_196_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974\u2010019\u20101679\u2010x"},{"key":"e_1_2_8_197_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460\u20109568.1995.tb01063.x"},{"key":"e_1_2_8_198_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01187086"},{"key":"e_1_2_8_199_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2018.08.004"},{"key":"e_1_2_8_200_1","doi-asserted-by":"publisher","DOI":"10.4103\/1673\u20105374.175042"},{"key":"e_1_2_8_201_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2023.10.004"},{"key":"e_1_2_8_202_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2017.01.006"},{"key":"e_1_2_8_203_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469\u20107580.2002.00046.x"},{"key":"e_1_2_8_204_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4322"},{"key":"e_1_2_8_205_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.24508"},{"key":"e_1_2_8_206_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10571\u2010017\u20100494\u20100"},{"key":"e_1_2_8_207_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201606052"},{"key":"e_1_2_8_208_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2018.01.054"},{"key":"e_1_2_8_209_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.50138"},{"key":"e_1_2_8_210_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.23949"},{"key":"e_1_2_8_211_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awt148"},{"key":"e_1_2_8_212_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2568\u201010.2011"},{"key":"e_1_2_8_213_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3281"},{"key":"e_1_2_8_214_1","doi-asserted-by":"publisher","DOI":"10.1006\/mcne.1997.0654"},{"key":"e_1_2_8_215_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006\u20108993(72)90215\u20106"},{"key":"e_1_2_8_216_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.08\u2010106666"},{"key":"e_1_2_8_217_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5207\u201014.2015"},{"key":"e_1_2_8_218_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M803191200"},{"key":"e_1_2_8_219_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3854\u201015.2016"},{"key":"e_1_2_8_220_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20309"},{"key":"e_1_2_8_221_1","doi-asserted-by":"publisher","DOI":"10.1177\/38.1.2294148"},{"key":"e_1_2_8_222_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1612136114"},{"key":"e_1_2_8_223_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.150656"},{"key":"e_1_2_8_224_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40478\u2010024\u201001720\u20103"},{"key":"e_1_2_8_225_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.120.6.1399"},{"key":"e_1_2_8_226_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcn.2003.11.007"},{"key":"e_1_2_8_227_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.106.5.1735"},{"key":"e_1_2_8_228_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200809008"},{"key":"e_1_2_8_229_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.52.3.615"},{"key":"e_1_2_8_230_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnen\/59.11.1002"},{"key":"e_1_2_8_231_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.14\u201001\u201000357.1994"},{"key":"e_1_2_8_232_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.3283935"},{"key":"e_1_2_8_233_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.4.1125"},{"key":"e_1_2_8_234_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.4.1130"},{"key":"e_1_2_8_235_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.49.30766"},{"key":"e_1_2_8_236_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.275.26.19883"},{"key":"e_1_2_8_237_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI113943"},{"key":"e_1_2_8_238_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.78.12.7545"},{"key":"e_1_2_8_239_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471\u20104159.1991.tb03469.x"},{"key":"e_1_2_8_240_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471\u20104159.1993.tb03322.x"}],"container-title":["Journal of the Peripheral Nervous System"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jns.70148","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jns.70148","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jns.70148","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T09:15:21Z","timestamp":1790068521000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jns.70148"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,25]]},"references-count":239,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1111\/jns.70148"],"URL":"https:\/\/doi.org\/10.1111\/jns.70148","archive":["Portico"],"relation":{},"ISSN":["1085-9489","1529-8027"],"issn-type":[{"value":"1085-9489","type":"print"},{"value":"1529-8027","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,25]]},"assertion":[{"value":"2025-04-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70148"}}