{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T06:51:10Z","timestamp":1790059870924,"version":"4.0.1"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,12,12]],"date-time":"2013-12-12T00:00:00Z","timestamp":1386806400000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Peripheral Nervous Sys"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To document the clinical features of Guillain\u2010Barr\u00e9 syndrome (<jats:styled-content style=\"fixed-case\">GBS<\/jats:styled-content>) in Australia, we performed a retrospective analysis of all patients admitted to several hospitals along the East Coast of Australia from 2000 to 2012. Using hospital records, we reviewed all patients with a diagnosis of <jats:styled-content style=\"fixed-case\">GBS<\/jats:styled-content> admitted to seven hospitals. From these, we report information of subjects who fulfilled standard diagnostic criteria. We excluded patients where inadequate information was available or who were under the age of 18. We report the features of 335 patients, in 228 of whom neurophysiological data were available. There were 168 cases of acute inflammatory demyelinating polyneuropathy (<jats:styled-content style=\"fixed-case\">AIDP<\/jats:styled-content>), 17 of acute motor axonal neuropathy (<jats:styled-content style=\"fixed-case\">AMAN<\/jats:styled-content>), 4 of acute motor and sensory axonal neuropathy (<jats:styled-content style=\"fixed-case\">AMSAN<\/jats:styled-content>), and 35 of Miller\u2010Fisher syndrome (<jats:styled-content style=\"fixed-case\">MFS<\/jats:styled-content>). The median age at onset was 52.5\u2009years (18\u201389\u2009years) with a male\u2009:\u2009female ratio of 1.61\u2009:\u20091. Upper respiratory tract infections were the most frequently identified trigger (151 subjects, 44.5%). Most patients were severely affected, with 42.7% of subjects bedbound, and an additional 24% requiring ventilatory support. <jats:styled-content style=\"fixed-case\">GBS<\/jats:styled-content> affects adults of all ages and usually follows a severe clinical course. In contrast to other autoimmune diseases, males are more frequently affected. A wide variety of triggering factors leads to a relatively stereotypical clinical syndrome. The most common variant of <jats:styled-content style=\"fixed-case\">GBS<\/jats:styled-content> in Australia is <jats:styled-content style=\"fixed-case\">AIDP<\/jats:styled-content>. This study shows that the clinical features of <jats:styled-content style=\"fixed-case\">GBS<\/jats:styled-content> in Australia are similar to that previously reported and confirms the male predominance, increased incidence with age, and frequent evidence of peripheral nerve demyelination as features of <jats:styled-content style=\"fixed-case\">GBS<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/jns5.12045","type":"journal-article","created":{"date-parts":[[2013,10,31]],"date-time":"2013-10-31T10:10:09Z","timestamp":1383214209000},"page":"316-320","source":"Crossref","is-referenced-by-count":25,"title":["Clinical features of patients with Guillain\u2010Barr\u00e9 syndrome at seven hospitals on the East Coast of Australia"],"prefix":"10.1111","volume":"18","author":[{"given":"Stefan","family":"Blum","sequence":"first","affiliation":[{"name":"Department of Neurology Royal Brisbane and Women's Hospital Herston Australia"},{"name":"Centre of Clinical Research University of Queensland, Herston Campus Herston Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Reddel","sequence":"additional","affiliation":[{"name":"Department of Neurology Concord Repatriation General Hospital Concord Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judy","family":"Spies","sequence":"additional","affiliation":[{"name":"Department of Neurology Royal Prince Alfred Hospital Camperdown Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela","family":"McCombe","sequence":"additional","affiliation":[{"name":"Department of Neurology Royal Brisbane and Women's Hospital Herston Australia"},{"name":"Centre of Clinical Research University of Queensland, Herston Campus Herston Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,12,12]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2003.12.004"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410270707"},{"key":"e_1_2_5_4_1","unstructured":"Australian Bureau of Statistics(2012). 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