{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T16:16:22Z","timestamp":1756311382012,"version":"3.40.5"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,11,21]],"date-time":"2019-11-21T00:00:00Z","timestamp":1574294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["BMRP148"],"award-info":[{"award-number":["BMRP148"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["sigmapubs.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Nursing Scholarship"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To explore the prevalence of hepatitis C virus (HCV) infection as well as the levels of liver health literacy and association with the health status of people with HCV through the nurse\u2010led community health development goal of global elimination.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A community\u2010based, cross\u2010sectional study was conducted between July 2018 and June 2019 in coastal Western Yunlin County, Taiwan. This study was conducted at five townships, and serum HCV\u00a0antibody (anti\u2010HCV) screening was used for the identification of potentially infected people by a collaborating local hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 1,963 adults from rural areas enrolled in this study, 321 (16.4%) were anti\u2010HCV positive, 237 (73.8%) reported that they were unaware of their HCV positivity, and none of them were provided information on direct\u2010acting antiviral agent therapy. The levels of anti\u2010HCV positivity were higher among female patients (<jats:italic>p<\/jats:italic> &lt; .05), elderly people (<jats:italic>p<\/jats:italic> &lt; .001), those with a low education level (<jats:italic>p<\/jats:italic> &lt; .001), and those from the Sihu Township within Yunlin County (<jats:italic>p<\/jats:italic> &lt; .001). Participants with anti\u2010HCV positivity tended to have lower intakes of vegetables (<jats:italic>p<\/jats:italic> &lt; .01) and fruit (<jats:italic>p<\/jats:italic> &lt; .05), a greater number of comorbidities (<jats:italic>p<\/jats:italic> &lt; .05), as well as a greater incidence of abnormal liver (<jats:italic>p<\/jats:italic> &lt; .001) and renal function (<jats:italic>p<\/jats:italic> &lt; .001) compared to those with anti\u2010HCV negativity. Multivariable linear regression analysis showed that the presence of HCV infection and a greater number of metabolic syndrome components were associated with poor liver and renal function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These findings showed a high prevalence of HCV infection among adults living in rural areas, who had low literacy levels on hepatitis, unhealthy lifestyles, and abnormal liver and renal function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Relevance<\/jats:title><jats:p>Clinicians and primary healthcare providers should initiate efforts to increase the levels of liver health literacy by increasing the accessibility to infection confirmation tests and reducing the number of barriers to the reception of antiviral treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jnu.12533","type":"journal-article","created":{"date-parts":[[2019,11,21]],"date-time":"2019-11-21T10:37:28Z","timestamp":1574332648000},"page":"128-135","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Liver Health Literacy and Health Status Among Adults With Hepatitis C: Implications for the Nursing Profession as Part of the 2030 Global Elimination Goal"],"prefix":"10.1111","volume":"52","author":[{"given":"Yu\u2010Chih","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Family Medicine Chang Gung Memorial Hospital Yunlin Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen\u2010Nan","family":"Chiu","sequence":"additional","affiliation":[{"name":"Department of Hepato\u2010Gastroenterology Chang Gung Memorial Hospital Yunlin Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Te\u2010Sheng","family":"Chang","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan, and Assistant Professor College of Medicine Chang Gung University Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tung\u2010Jung","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Disease and Critical Care, Chang Gung Memorial Hospital, Yunlin, Taiwan, and Department of Respiratory Care Chang Gung University of Science and Technology Chiayi Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8980-1300","authenticated-orcid":false,"given":"Mei\u2010Yen","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Nursing, Chang Gung University of Science and Technology, Chiayi, Taiwan, and Department of Nursing, Chang Gung University, Taoyuan, Taiwan, and Research Fellow Department of Cardiology Chang Gung Memorial Hospital Yunlin Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,11,21]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_7_2_1","DOI":"10.1016\/j.ijcard.2016.06.337"},{"doi-asserted-by":"publisher","key":"e_1_2_7_3_1","DOI":"10.1111\/j.1365-2893.2009.01237.x"},{"doi-asserted-by":"publisher","key":"e_1_2_7_4_1","DOI":"10.1586\/14737167.2015.1076337"},{"doi-asserted-by":"publisher","key":"e_1_2_7_5_1","DOI":"10.1016\/S1473-3099(19)30073-8"},{"doi-asserted-by":"publisher","key":"e_1_2_7_6_1","DOI":"10.1186\/s12874-018-0515-9"},{"volume-title":"Viral hepatitis","year":"2019","author":"Centers for Disease Control and Prevention","key":"e_1_2_7_7_1"},{"doi-asserted-by":"publisher","key":"e_1_2_7_8_1","DOI":"10.1016\/S1473-3099(19)30170-7"},{"issue":"7","key":"e_1_2_7_9_1","first-page":"739","article-title":"Caring people of hepatitis C carriers living with adverse effects during antiviral treatment: A longitudinal study","volume":"7","author":"Chiu W. 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