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This study analyzes the normal somatotopy of those motoneurons and describes its changes over time after a crush injury to the <jats:styled-content style=\"fixed-case\">RLN<\/jats:styled-content>. In the control group (control group 1, <jats:italic>n\u2005<\/jats:italic>=\u20059 rats), the posterior cricoarytenoid (<jats:styled-content style=\"fixed-case\">PCA<\/jats:styled-content>) and thyroarytenoid (<jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content>) muscles were injected with cholera toxin\u2010B. In the experimental groups the left <jats:styled-content style=\"fixed-case\">RLN<\/jats:styled-content> of each animal was crushed with a fine tip forceps and, after several survival periods (1, 2, 4, 8, 12\u2005weeks; minimum six rats per time), the <jats:styled-content style=\"fixed-case\">PCA<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content> muscles were injected as described above. After each surgery, the motility of the vocal folds was evaluated. Additional control experiments were performed; the second control experiment (control group 2, <jats:italic>n\u2005<\/jats:italic>=\u20056 rats) was performed labeling the <jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PCA<\/jats:styled-content> immediately prior to the section of the superior laryngeal nerve (SLN), in order to eliminate the possibility of accidental labeling of the cricothyroid (CT) muscle by spread from the injection site. The third control group (control group 3, <jats:italic>n\u2005<\/jats:italic>=\u20055 rats) was included to determine if there is some sprouting from the SLN into the territories of the <jats:styled-content style=\"fixed-case\">RLN<\/jats:styled-content> after a crush of this last nerve. One\u2005week after the crush injury of the <jats:styled-content style=\"fixed-case\">RLN<\/jats:styled-content>, the <jats:styled-content style=\"fixed-case\">PCA<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content> muscles were injected immediately before the section of the SLN. The results show that a single population of neurons represents each muscle with the <jats:styled-content style=\"fixed-case\">PCA<\/jats:styled-content> in the most rostral position followed caudalwards by the <jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content>. One week post\u2010<jats:styled-content style=\"fixed-case\">RLN<\/jats:styled-content> injury, both the somatotopy and the number of labeled motoneurons changed, where the labeled neurons were distributed randomly; in addition, an area of topographical overlap of the two populations was observed and vocal fold mobility was lost. In the rest of the survival periods, the overlapping area is larger, but the movement of the vocal folds tends to recover. After 12\u2005weeks of survival, the disorganization within the Amb is the largest, but the number of motoneurons is similar to control, and all animals recovered the movement of the left vocal fold. Our additional controls indicate that no tracer spread to the CT muscle occurred, and that many of the labeled motoneurons from the <jats:styled-content style=\"fixed-case\">PCA<\/jats:styled-content> after 1\u2005week post\u2010<jats:styled-content style=\"fixed-case\">RLN<\/jats:styled-content> injury correspond to motoneurons whose axons travel in the SLN. Therefore, it seems that after <jats:styled-content style=\"fixed-case\">RLN<\/jats:styled-content> injury there is a collateral sprouting and collateral innervation. Although the somatotopic organization of the Amb is lost after a crush injury of the <jats:styled-content style=\"fixed-case\">RLN<\/jats:styled-content> and does not recover in the times studied here, the movement of the vocal folds as well as the number of neurons that supply the <jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content> and the <jats:styled-content style=\"fixed-case\">PCA<\/jats:styled-content> muscles recovered within 8\u2005weeks, indicating that the central nervous system of the rat has a great capacity of plasticity.<\/jats:p>","DOI":"10.1111\/joa.12031","type":"journal-article","created":{"date-parts":[[2013,2,28]],"date-time":"2013-02-28T16:22:03Z","timestamp":1362068523000},"page":"451-461","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Reorganization of laryngeal motoneurons after crush injury in the recurrent laryngeal nerve of the rat"],"prefix":"10.1111","volume":"222","author":[{"given":"Ignacio","family":"Hern\u00e1ndez\u2010Morato","sequence":"first","affiliation":[{"name":"Departamento de Anatom\u00eda y Embriolog\u00eda Humana I Facultad de Medicina Universidad Complutense de Madrid Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco J.","family":"Valderrama\u2010Canales","sequence":"additional","affiliation":[{"name":"Departamento de Anatom\u00eda y Embriolog\u00eda Humana I Facultad de Medicina Universidad Complutense de Madrid Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Berdugo","sequence":"additional","affiliation":[{"name":"Departamento de Anatom\u00eda y Embriolog\u00eda Humana I Facultad de Medicina Universidad Complutense de Madrid Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gonzalo","family":"Arias","sequence":"additional","affiliation":[{"name":"Departamento de Anatom\u00eda 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