{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T15:47:44Z","timestamp":1791301664869,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,4,29]],"date-time":"2013-04-29T00:00:00Z","timestamp":1367193600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Anatomy"],"published-print":{"date-parts":[[2013,7]]},"abstract":"Abstract<\/jats:title>\n \n A rostrocaudal pathway connecting the temporal and parietal lobes was described in monkeys using autoradiography and was named the\n m<\/jats:styled-content>\n iddle\n l<\/jats:styled-content>\n ongitudinal\n f<\/jats:styled-content>\n asciculus (MdLF). Recently, the use of diffusion tensor tractography has allowed it to be depicted in human volunteers. In the present study, a technique of fiber dissection was used in 18 cadaveric human brains to investigate the presence of this fasciculus and to detail its anatomical relationships. On the basis of our findings, fiber dissection provides evidence for a long horizontal bundle medial to the arcuate fasciculus and extending to the superior temporal gyrus. Its fibers occupy the lateral\u2010most layer of the upper portion of the stratum sagittale and partially cover the inferior fronto\u2010occipital fasciculus, which is situated deeper and slightly inferiorly. Whereas\n M<\/jats:styled-content>\n d\n LF<\/jats:styled-content>\n fibers continue on a relatively superficial level to reach the\n superior temporal gyrus<\/jats:styled-content>\n , the inferior fronto\u2010occipital fasciculus penetrates the deep temporal white matter and crosses the insular lobe. Although diffusion tensor imaging suggests that the\n M<\/jats:styled-content>\n d\n LF<\/jats:styled-content>\n terminates in the angular gyrus, this was not confirmed by the present study. These long association fibers continue onward posteriorly into upper portions of the occipital lobe. Further studies are needed to understand the role of the\n M<\/jats:styled-content>\n d\n LF<\/jats:styled-content>\n in brain function.\n <\/jats:p>","DOI":"10.1111\/joa.12055","type":"journal-article","created":{"date-parts":[[2013,4,29]],"date-time":"2013-04-29T04:04:43Z","timestamp":1367208283000},"page":"38-45","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":96,"title":["Evidence of a\n m<\/scp>\n iddle\n l<\/scp>\n ongitudinal\n f<\/scp>\n asciculus in the human brain from fiber dissection"],"prefix":"10.1111","volume":"223","author":[{"given":"Igor Lima","family":"Maldonado","sequence":"first","affiliation":[{"name":"Depart. Biomorfologia Instituto de Ci\u00eancias da Sa\u00fade, Universidade Federal da Bahia Salvador Brazil"},{"name":"Divis\u00e3o de Neurologia e Epidemiologia (DINEP), Hosp Universit\u00e1rio Prof. Edgard Santos Salvador Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas Menjot","family":"de Champfleur","sequence":"additional","affiliation":[{"name":"Institut de Neurosciences de Montpellier (INM) INSERM U1051\/E4 Montpellier France"},{"name":"Department de Neuroradiologie Centre Hospitalier Universitaire de Montpellier Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Velut","sequence":"additional","affiliation":[{"name":"CHRU de Tours Service de Neurochirurgie Tours France"},{"name":"Universit\u00e9 Fran\u00e7ois Rabelais de Tours Laboratoire d'Anatomie Tours France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Destrieux","sequence":"additional","affiliation":[{"name":"CHRU de Tours Service de Neurochirurgie Tours France"},{"name":"Universit\u00e9 Fran\u00e7ois Rabelais de Tours Laboratoire d'Anatomie Tours France"},{"name":"UMRS INSERM U930 CNRS ERL 3106 Universit\u00e9 Fran\u00e7ois Rabelais de Tours Tours France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilyess","family":"Zemmoura","sequence":"additional","affiliation":[{"name":"CHRU de Tours Service de Neurochirurgie Tours France"},{"name":"Universit\u00e9 Fran\u00e7ois Rabelais de Tours Laboratoire d'Anatomie Tours France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugues","family":"Duffau","sequence":"additional","affiliation":[{"name":"Institut de Neurosciences de Montpellier (INM) INSERM U1051\/E4 Montpellier France"},{"name":"Department de Neuroradiologie Centre Hospitalier Universitaire de Montpellier Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,4,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(94)80775-1"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-282X2005000200011"},{"key":"e_1_2_8_4_1","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1002\/hbm.21082","article-title":"Is the human left middle longitudinal fascicle essential for language? A brain electrostimulation study","volume":"32","author":"Witt Hamer P","year":"2010","journal-title":"Hum Brain Mapp"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1227\/01.neu.0000333767.05328.49"},{"key":"e_1_2_8_6_1","volume-title":"World Intellectual Property Organization. IB Image Neurography and Diffusion Anisotropy Imaging","author":"Filler AG","year":"1993"},{"key":"e_1_2_8_7_1","first-page":"247","article-title":"Erleichterung der makroskopischen Praeparation des Gehirns durch den Gefrierprozess","volume":"36","author":"Klingler J","year":"1935","journal-title":"Schweiz Arch Neurol Psychiatr"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2007.06.041"},{"key":"e_1_2_8_9_1","unstructured":"LudwigE KlinglerJ(1956)Atlas cerebri humani. Der innere Bau des Gehirns dargestellt auf Grund makroskopischer Pr\u00e4parate. Anatomisches Institut der Universit\u00e4t Basel. Basel: S. Karger."},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhn124"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2009.07.015"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000348564.28415.FA"},{"key":"e_1_2_8_13_1","volume-title":"Introduction to Diffusion Tensor Imaging","author":"Mori S","year":"2007"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00237280"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2004.101.5.0739"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-200008000-00028"}],"container-title":["Journal of Anatomy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjoa.12055","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joa.12055","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/joa.12055","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joa.12055","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T04:23:35Z","timestamp":1698639815000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joa.12055"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,29]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["10.1111\/joa.12055"],"URL":"https:\/\/doi.org\/10.1111\/joa.12055","archive":["Portico"],"relation":{},"ISSN":["0021-8782","1469-7580"],"issn-type":[{"value":"0021-8782","type":"print"},{"value":"1469-7580","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,29]]},"assertion":[{"value":"2013-04-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-04-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}