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This neuroanatomical element is formed by different subregions, involved in visuo\u2010spatial integration, memory and self\u2010awareness. We analysed the midsagittal brain shape in a sample of adult humans (<jats:italic>n\u2005<\/jats:italic>=\u200590) to evidence the patterns of variability and geometrical organization of this area. Interestingly, the major brain covariance pattern within adult humans is strictly associated with the relative proportions of the precuneus. Its morphology displays a marked individual variation, both in terms of geometry (mostly in its longitudinal dimensions) and anatomy (patterns of convolution). No patent differences are evident between males and females, and the allometric effect of size is minimal. However, in terms of morphology, the precuneus does not represent an individual module, being influenced by different neighbouring structures. Taking into consideration the apparent involvement of the precuneus in higher\u2010order human brain functions and evolution, its wide variation further stresses the important role of these deep parietal areas in modern neuroanatomical organization.<\/jats:p>","DOI":"10.1111\/joa.12155","type":"journal-article","created":{"date-parts":[[2014,1,8]],"date-time":"2014-01-08T05:57:04Z","timestamp":1389160624000},"page":"367-376","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["Midsagittal brain variation and <scp>MRI<\/scp> shape analysis of the precuneus in adult individuals"],"prefix":"10.1111","volume":"224","author":[{"given":"Emiliano","family":"Bruner","sequence":"first","affiliation":[{"name":"Centro Nacional de Investigaci\u00f3n sobre la Evoluci\u00f3n Humana Burgos Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giz\u00e9h","family":"Rangel de L\u00e1zaro","sequence":"additional","affiliation":[{"name":"Universitat Rovira i Virgili Tarragona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Manuel","family":"de la Cu\u00e9tara","sequence":"additional","affiliation":[{"name":"Centro Nacional de Investigaci\u00f3n sobre la Evoluci\u00f3n Humana Burgos Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Mart\u00edn\u2010Loeches","sequence":"additional","affiliation":[{"name":"Centro UCM\u2010ISCIII de Evoluci\u00f3n y Comportamiento Humanos Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Colom","sequence":"additional","affiliation":[{"name":"Universidad Aut\u00f3noma de Madrid\/Fundaci\u00f3n CIEN\u2010Fundaci\u00f3n Reina Sof\u00eda Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi I. 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