{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T15:24:46Z","timestamp":1791213886527,"version":"4.1.0"},"reference-count":41,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,9,11]],"date-time":"2015-09-11T00:00:00Z","timestamp":1441929600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003407","name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Anatomy"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study evaluates the pathogenetic role of the perineural connective tissue and foot fasciae in Civinini\u2013Morton's neuroma. Eleven feet (seven male, four female; mean age: 70.9 years) were dissected to analyse the anatomy of inter\u2010metatarsal space, particularly the dorsal and plantar fasciae and metatarsal transverse ligament (<jats:styled-content style=\"fixed-case\">DMTL<\/jats:styled-content>). The macrosections were prepared for microscopic analysis. Ten Civinini\u2013Morton neuromas obtained from surgery were also analysed. Magnetic resonance images (MRIs) from 40 patients and 29 controls were compared. Dissections showed that the width of the inter\u2010metatarsal space is established by two fibrous structures: the dorsal foot fascia and the<jats:styled-content style=\"fixed-case\">DMTL<\/jats:styled-content>, which, together, connect the metatarsal bones and resist their splaying. Interosseous muscles spread out into the dorsal fascia of the foot, defining its basal tension. The common digital plantar nerve (CDPN) is encased in concentric layers of fibrous and loose connective tissue, continuous with the vascular sheath and deep foot fascia. Outside this sheath, fibroelastic septa, from<jats:styled-content style=\"fixed-case\">DMTL<\/jats:styled-content>to plantar fascia, and little fat lobules are present, further protecting the nerve against compressive stress. The<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>study revealed high inter\u2010individual variability in the forefoot structures, although only the thickness of the dorsal fascia represented a statistically significant difference between cases and controls. It was hypothesized that alterations in foot support and altered biomechanics act on the interosseous muscles, increasing the stiffness of the dorsal fascia, particularly at the points where these muscles are inserted. Chronic rigidity of this fascia increases the stiffness of the inter\u2010metatarsal space, leading to entrapment of the CDPN.<\/jats:p>","DOI":"10.1111\/joa.12371","type":"journal-article","created":{"date-parts":[[2015,9,11]],"date-time":"2015-09-11T11:43:46Z","timestamp":1441971826000},"page":"654-664","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["The role of fasciae in<scp>C<\/scp>ivinini\u2013<scp>M<\/scp>orton's syndrome"],"prefix":"10.1111","volume":"227","author":[{"given":"Carla","family":"Stecco","sequence":"first","affiliation":[{"name":"Department of Molecular Medicine University of Padova Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilaria","family":"Fantoni","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine University of Padova Padova Italy"},{"name":"Orthopedic and Trauma Clinic Department of Surgery Oncology and Gastroenterology 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