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The salivary glands of these species have been of particular research interest due to their structural variability among chiropterans with different types of diets. Myoepithelial cells (MECs), which support and facilitate the expulsion of saliva from the secretory portions of salivary glands, are very important for their function; however, this cell type has not been extensively studied in the salivary glands of bats. In this study, we characterized the MECs in the major salivary glands of the fruit bat <jats:italic>Artibeus jamaicensis<\/jats:italic>. Herein, we describe the morphology of the parotid, submandibular and sublingual glands of <jats:italic>A.\u00a0jamaicensis<\/jats:italic> at the light\u2010 and electro\u2010microscopic level and the distribution of MECs in these glands, as defined by their expression of smooth\u2010muscle markers such as \u03b1\u2010smooth muscle actin (SMA\u03b1) and desmin, and of epithelial cell markers, such as KRT14. We found that the anatomical locations of the major salivary glands in this bat species are similar to those of humans, except that the bat sublingual gland appears to be unique, extending to join the contralateral homologous gland. Morphologically, the parotid gland has the characteristics of a mixed\u2010secretory gland, whereas the submandibular and sublingual glands were identified as mucous\u2010secretory glands. MECs positive for SMA\u03b1, KRT14 and desmin were found in all of the structural components of the three glands, except in their excretory ducts. Desmin is expressed at a lower level in the parotid gland than in the other glands. Our results suggest that the major salivary glands of <jats:italic>A.\u00a0jamaicensis,<\/jats:italic> although anatomically and structurally similar to those of humans, play different physiological roles that can be attributed to the dietary habits of this species.<\/jats:p>","DOI":"10.1111\/joa.12481","type":"journal-article","created":{"date-parts":[[2016,5,11]],"date-time":"2016-05-11T06:31:49Z","timestamp":1462948309000},"page":"302-313","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Characterization of the myoepithelial cells in the major salivary glands of the fruit bat <i>Artibeus jamaicensis<\/i>"],"prefix":"10.1111","volume":"229","author":[{"given":"Julio","family":"Guerrero\u2010Hern\u00e1ndez","sequence":"first","affiliation":[{"name":"Department of Cell Biology and Physiology Instituto de Investigaciones Biom\u00e9dicas Universidad Nacional Aut\u00f3noma de M\u00e9xico Ciudad Universitaria M\u00e9xico D.F. M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norma","family":"Moreno\u2010Mendoza","sequence":"additional","affiliation":[{"name":"Department of Cell Biology and Physiology Instituto de Investigaciones Biom\u00e9dicas Universidad Nacional Aut\u00f3noma de M\u00e9xico Ciudad Universitaria M\u00e9xico D.F. 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