{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T00:06:07Z","timestamp":1791590767623,"version":"4.3.4"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,11,11]],"date-time":"2018-11-11T00:00:00Z","timestamp":1541894400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Anatomy"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The morphology of the connective tissue may play an important role in locomotor mechanics. Recent research has revealed an association between increased fascia thickness and reduced joint flexibility in patients with chronic pain. The present study aimed to examine the relationship of both factors in healthy individuals, additionally testing the hypothesis that older subjects display a higher fascia thickness. Young (\n                    <jats:italic>n\u2005<\/jats:italic>\n                    =\u200518, 22\u2005\u00b1\u20051\u2005years) and old (\n                    <jats:italic>n\u2005<\/jats:italic>\n                    =\u200517, 69\u2005\u00b1\u20054\u2005years) healthy females were recruited for a quasi\u2010experimental, cross\u2010sectional trial. All participants underwent standardized ultrasound\u2010based thickness measurements of the deep fasciae of the trunk and lower limb. Flexibility was assessed using sit and reach testing (hamstring extensibility) and the Schober test (lumbar flexion and extension). Systematic between\u2010group differences of fascia thickness and variable associations (i.e. fascia thickness and flexibility) were detected using non\u2010parametric data analyses. Young adults exhibited higher fascia thickness of the anterior and posterior lower leg, anterior thigh and abdominal wall (+12.3\u201325.8%,\n                    <jats:italic>P\u2005<\/jats:italic>\n                    &lt;\u20050.05). Conversely, older participants showed higher thickness in the lumbar spine (+40.0\u201376.7%,\n                    <jats:italic>P\u2005<\/jats:italic>\n                    &lt;\u20050.05). Correlations of both body mass and fascia thickness (\n                    <jats:italic>\u03c4<\/jats:italic>\n                    \u2005=\u20050.45\u20130.75,\n                    <jats:italic>P\u2005<\/jats:italic>\n                    &lt;\u20050.05), as well as flexibility and fascia thickness (\n                    <jats:italic>\u03c4\u2005<\/jats:italic>\n                    =\u20050.38\u20130.42,\n                    <jats:italic>P\u2005<\/jats:italic>\n                    &lt;\u20050.05) were found. Age\u2010related changes in fascia thickness may be a contributing factor of restrictions in joint range of motion. Further study delineating the cause\u2013effect triangle of body mass index, flexibility and fascia thickness is necessary.\n                  <\/jats:p>","DOI":"10.1111\/joa.12902","type":"journal-article","created":{"date-parts":[[2018,11,12]],"date-time":"2018-11-12T00:49:13Z","timestamp":1541983753000},"page":"43-49","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":130,"title":["Fascia thickness, aging and flexibility: is there an association?"],"prefix":"10.1111","volume":"234","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9147-2369","authenticated-orcid":false,"given":"Jan","family":"Wilke","sequence":"first","affiliation":[{"name":"Department of Sports Medicine Goethe University Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronica","family":"Macchi","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine Institute of Human Anatomy University of Padova Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"De Caro","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine Institute of Human Anatomy University of Padova Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Stecco","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine Institute of Human Anatomy University of Padova Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,11,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-013-9600-5"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ptsp.2011.11.001"},{"key":"e_1_2_8_4_1","first-page":"202","article-title":"Relationships of age and sex with range of motion of seventeen joint actions in humans","volume":"6","author":"Bell RD","year":"1981","journal-title":"Can 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