{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T07:11:16Z","timestamp":1791616276826,"version":"4.3.4"},"reference-count":178,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,12,13]],"date-time":"2018-12-13T00:00:00Z","timestamp":1544659200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004488","name":"Hrvatska Zaklada za Znanost","doi-asserted-by":"publisher","award":["CSF\u2010DOK\u201010\u20102015"],"award-info":[{"award-number":["CSF\u2010DOK\u201010\u20102015"]}],"id":[{"id":"10.13039\/501100004488","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004488","name":"Hrvatska Zaklada za Znanost","doi-asserted-by":"publisher","award":["CSF\u2010IP\u201009 2014\u20104517"],"award-info":[{"award-number":["CSF\u2010IP\u201009 2014\u20104517"]}],"id":[{"id":"10.13039\/501100004488","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["KK.01.1.1.01.0007"],"award-info":[{"award-number":["KK.01.1.1.01.0007"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Anatomy"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The objective of this paper was to collect normative data essential for analyzing the subplate (SP) role in pathogenesis of developmental disorders, characterized by abnormal circuitry, such as hypoxic\u2010ischemic lesions, autism and schizophrenia. The main cytological features of the SP, such as low cell density, early differentiation of neurons and glia, plexiform arrangement of axons and dendrites, presence of synapses and a large amount of extracellular matrix (ECM) distinguish this compartment from the cell\u2010dense cortical plate (CP; towards pia) and large fiber bundles of external axonal strata of fetal white matter (towards ventricle). For SP delineation from these adjacent layers based on combined cytological criteria, we analyzed the sublaminar distribution of different microstructural elements and the associated maturational gradients throughout development, using immunocytochemical and histological techniques on postmortem brain material (Zagreb Neuroembryological Collection). The analysis revealed that the SP compartment of the lateral neocortex shows changes in laminar organization throughout fetal development: the monolayer in the early fetal period (presubplate) undergoes dramatic bilaminar transformation between 13 and 15 postconceptional weeks (PCW), followed by subtle sublamination in three \u2018floors\u2019 (deep, intermediate, superficial) of midgestation (15\u201321 PCW). During the stationary phase (22\u201328 PCW), SP persists as a trilaminar compartment, gradually losing its sublaminar organization towards the end of gestation and remains as a single layer of SP remnant in the newborn brain. Based on these sublaminar transformations, we have documented developmental changes in the distribution, maturational gradients and expression of molecular markers in SP synapses, transitional forms of astroglia, neurons and ECM, which occur concomitantly with the ingrowth of thalamo\u2010cortical, basal forebrain and cortico\u2010cortical axons in a deep to superficial fashion. The deep SP is the zone of ingrowing axons \u2013 \u2018entrance (ingrowth) zone\u2019. The process of axonal ingrowth begins with thalamo\u2010cortical fibers and basal forebrain afferents, indicating an oblique geometry. During the later fetal period, deep SP receives long cortico\u2010cortical axons exhibiting a tangential geometry. Intermediate SP (\u2018proper\u2019) is the navigation and \u2018nexus\u2019 sublamina consisting of a plexiform arrangement of cellular elements providing guidance and substrate for axonal growth, and also containing transient connectivity of dendrites and axons in a tangential plane without radial boundaries immersed in an ECM\u2010rich continuum. Superficial SP is the axonal accumulation (\u2018waiting compartment\u2019) and target selection zone, indicating a dense distribution of synaptic markers, accumulation of thalamo\u2010cortical axons (around 20 PCW), overlapping with dendrites from layer VI neurons. In the late preterm brain period, superficial SP contains a chondroitin sulfate non\u2010immunoreactive band. The developmental dynamics for the distribution of neuronal, glial and ECM markers comply with sequential ingrowth of afferents in three levels of SP: ECM and synaptic markers shift from deep to superficial SP, with transient forms of glia following this arrangement, and calretinin neurons are concentrated in the SP during the formation phase. These results indicate developmental and morphogenetic roles in the SP cellular (transient glia, neurons and synapses) and ECM framework, enabling the spatial accommodation, navigation and establishment of numerous connections of cortical pathways in the expanded human brain. The original findings of early developmental dynamics of transitional subtypes of astroglia, calretinin neurons, ECM and synaptic markers presented in the SP are interesting in the light of recent concepts concerning its functional and morphogenetic role and an increasing interest in SP as a prospective substrate of abnormalities in cortical circuitry, leading to a cognitive deficit in different neurodevelopmental disorders.<\/jats:p>","DOI":"10.1111\/joa.12920","type":"journal-article","created":{"date-parts":[[2018,12,14]],"date-time":"2018-12-14T01:20:59Z","timestamp":1544750459000},"page":"481-506","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":61,"title":["Sublaminar organization of the human subplate: developmental changes in the distribution of neurons, glia, growing axons and extracellular matrix"],"prefix":"10.1111","volume":"235","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4090-4114","authenticated-orcid":false,"given":"Ivica","family":"Kostovi\u0107","sequence":"first","affiliation":[{"name":"Croatian Institute for Brain Research School of Medicine University of Zagreb Zagreb Croatia"},{"name":"Centre of Excellence for Basic, Clinical and Translational Neuroscience Zagreb Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iris \u017duni\u0107","family":"I\u0161asegi","sequence":"additional","affiliation":[{"name":"Croatian Institute for Brain Research School of Medicine University of Zagreb Zagreb Croatia"},{"name":"Centre of Excellence for Basic, Clinical and Translational Neuroscience Zagreb Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u017deljka","family":"Krsnik","sequence":"additional","affiliation":[{"name":"Croatian Institute for Brain Research School of Medicine University of Zagreb Zagreb Croatia"},{"name":"Centre of Excellence for Basic, Clinical and Translational Neuroscience Zagreb Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,12,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bht254"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2014.06.030"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ne.17.030194.001153"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-016-1343-5"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-2236(98)01349-6"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.21-04-01302.2001"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhr176"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2012.07.006"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-3639.2004.tb00492.x"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhm184"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.14-06-03500.1994"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1101\/SQB.1990.055.01.048"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.13-07-02801.1993"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/4.1.78"},{"key":"e_1_2_9_16_1","volume-title":"Vergleichende Lokalisationslehre der Grosshirnrinde im ihrem Prinzipien dargestellt auf Grund des Zellenbaues","author":"Brodmann K","year":"1909"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-006-0287-0"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/3.5.476"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2252"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(78)90721-7"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0896-6273(88)90078-5"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.09-05-01648.1989"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/325617a0"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/neuroglia1010003"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2004.02.003"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/neu.10205"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19990927)412:3<515::AID-CNE10>3.0.CO;2-1"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1024130211265"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2014.12.060"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19970324)379:4<515::AID-CNE4>3.0.CO;2-5"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2011.05.015"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/0166-2236(93)90151-B"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-397025-1.00360-2"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1610078113"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3980-04.2005"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature09612"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresrev.2010.01.001"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1115807"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19980817)398:1<105::AID-CNE7>3.0.CO;2-5"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1991.66.6.2059"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.10-08-02601.1990"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.4103\/1673-5374.226378"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1542795"},{"issue":"3","key":"e_1_2_9_44_1","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1242\/dev.117.3.1031","article-title":"A role for subplate neurons in the patterning of connections from thalamus to neocortex","volume":"117","author":"Ghosh A","year":"1993","journal-title":"Development"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/347179a0"},{"key":"e_1_2_9_46_1","first-page":"41","article-title":"Dynamic expression of calretinin in embryonic and early fetal human cortex","volume":"8","author":"Gonz\u00e1lez G\u00f3mez M","year":"2014","journal-title":"Front Neuroanat"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm1739"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/11.5.400"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.22-16-07165.2002"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0752-06.2006"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhn061"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature08845"},{"key":"e_1_2_9_53_1","first-page":"216","article-title":"Neurexins 1\u20133 each have a distinct pattern of expression in the early developing human cerebral cortex","volume":"27","author":"Harkin LF","year":"2017","journal-title":"Cereb Cortex"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnen\/59.5.385"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhr336"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnana.2014.00050"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhs137"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3915"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhn195"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhy036"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2006.06.009"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2769-08.2009"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19971020)387:2<167::AID-CNE1>3.0.CO;2-Z"},{"key":"e_1_2_9_64_1","first-page":"5","article-title":"Oligodendrocyte development and the onset of myelination in the human fetal brain","volume":"3","author":"Jackocevski I","year":"2009","journal-title":"Front Neuroanat"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20134"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-63486-3.00007-4"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-55557-2_1"},{"issue":"10","key":"e_1_2_9_68_1","first-page":"2671","article-title":"Structural, immunocytochemical and MR imaging properties of periventricular crossroads of growing cortical pathways in preterm infants","volume":"26","author":"Juda\u0161 M","year":"2005","journal-title":"AJNR Am J Neuroradiol"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2010.01283.x"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2010.01284.x"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2011.05993.x"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200410050-00001"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.3389\/neuro.05.016.2009"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-neuro-060909-153244"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1084152"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2008.07.026"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2006.05.007"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature03132"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2006.108837"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2015.00100"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(86)90077-1"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902190405"},{"key":"e_1_2_9_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2006.07.001"},{"key":"e_1_2_9_84_1","first-page":"107","article-title":"Transient patterns of organization of the human fetal brain","volume":"39","author":"Kostovi\u0107 I","year":"1998","journal-title":"CMJ"},{"key":"e_1_2_9_85_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.10069"},{"key":"e_1_2_9_86_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0012162206000831"},{"key":"e_1_2_9_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2007.04.018"},{"key":"e_1_2_9_88_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2010.01811.x"},{"key":"e_1_2_9_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-397025-1.00193-7"},{"key":"e_1_2_9_90_1","first-page":"111","article-title":"The comparative analysis of the laminar pattern of the synaptogenesis in limbic and neocortical areas of human fetal cortex","volume":"23","author":"Kostovi\u0107 I","year":"1975","journal-title":"Exp Brain Res"},{"key":"e_1_2_9_91_1","first-page":"95","article-title":"A new interpretation of the laminar development of cerebral cortex: synaptogenesis in different layers of neopallium in the human fetus","volume":"178","author":"Kostovi\u0107 I","year":"1974","journal-title":"Anat Rec"},{"key":"e_1_2_9_92_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01205159"},{"key":"e_1_2_9_93_1","doi-asserted-by":"crossref","first-page":"LP\u201042","DOI":"10.1523\/JNEUROSCI.04-01-00025.1984","article-title":"Development of prestriate visual projections in the monkey and human fetal cerebrum revealed by transient cholinesterase staining","volume":"4","author":"Kostovi\u0107 I","year":"1984","journal-title":"J Neurosci"},{"key":"e_1_2_9_94_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902970309"},{"key":"e_1_2_9_95_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00999489"},{"key":"e_1_2_9_96_1","first-page":"155","article-title":"The early development of glia in human neocortex","volume":"17","author":"Kostovi\u0107 I","year":"1975","journal-title":"Rad Jug Akad Znan Unijet Nat Sci Ser"},{"key":"e_1_2_9_97_1","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1387\/ijdb.1687658","article-title":"Zagreb research collection of human brains for developmental neurobiologist and clinical neuroscientist","volume":"35","author":"Kostovi\u0107 I","year":"1991","journal-title":"Int J Dev Biol"},{"key":"e_1_2_9_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(91)90082-5"},{"key":"e_1_2_9_99_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/12.5.536"},{"key":"e_1_2_9_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijdevneu.2010.09.005"},{"key":"e_1_2_9_101_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-012-0496-0"},{"key":"e_1_2_9_102_1","first-page":"139","article-title":"Developmental dynamics of radial vulnerability in the cerebral compartments in preterm infants and neonates","volume":"5","author":"Kostovi\u0107 I","year":"2014","journal-title":"Front Neurol"},{"key":"e_1_2_9_103_1","doi-asserted-by":"publisher","DOI":"10.1111\/cns.12333"},{"key":"e_1_2_9_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(76)90175-X"},{"key":"e_1_2_9_105_1","doi-asserted-by":"publisher","DOI":"10.1159\/000145727"},{"key":"e_1_2_9_106_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2017.00233"},{"key":"e_1_2_9_107_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.23.13491"},{"key":"e_1_2_9_108_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901930316"},{"key":"e_1_2_9_109_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1075"},{"key":"e_1_2_9_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.01.042"},{"key":"e_1_2_9_111_1","doi-asserted-by":"publisher","DOI":"10.3389\/neuro.05.019.2009"},{"key":"e_1_2_9_112_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.05-04-01062.1985"},{"key":"e_1_2_9_113_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.127.24.5253"},{"key":"e_1_2_9_114_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2018.00118"},{"key":"e_1_2_9_115_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2396-17.2017"},{"key":"e_1_2_9_116_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.2475909"},{"key":"e_1_2_9_117_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.14-04-01892.1994"},{"key":"e_1_2_9_118_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.23-08-03308.2003"},{"key":"e_1_2_9_119_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903170107"},{"key":"e_1_2_9_120_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.20-05-01858.2000"},{"key":"e_1_2_9_121_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2017.00078"},{"key":"e_1_2_9_122_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903550410"},{"key":"e_1_2_9_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-63486-3.00007-4"},{"issue":"4","key":"e_1_2_9_124_1","first-page":"5","article-title":"The ontogenesis of cortical circuitry: the spatial distribution of synapses in somesthetic cortex of newborn dog","volume":"42","author":"Molliver ME","year":"1970","journal-title":"Ergeb Anat Entwicklungsgesch"},{"key":"e_1_2_9_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(73)90741-5"},{"key":"e_1_2_9_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/0166-2236(95)93935-Q"},{"key":"e_1_2_9_127_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-53860-4.00003-9"},{"key":"e_1_2_9_128_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.18-15-05723.1998"},{"key":"e_1_2_9_129_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2012.08119.x"},{"key":"e_1_2_9_130_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhn206"},{"key":"e_1_2_9_131_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3886-10.2011"},{"key":"e_1_2_9_132_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1405253111"},{"key":"e_1_2_9_133_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902710306"},{"key":"e_1_2_9_134_1","first-page":"1","article-title":"Topography of the monoamine neuron systems in the human brain as revealed in fetuses","volume":"388","author":"Nobin A","year":"1973","journal-title":"Acta Physiol Scand Suppl"},{"key":"e_1_2_9_135_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn1172"},{"key":"e_1_2_9_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2006.08.004"},{"key":"e_1_2_9_137_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4707-08.2009"},{"key":"e_1_2_9_138_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-61779-452-0_3"},{"key":"e_1_2_9_139_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.13-04-01441.1993"},{"key":"e_1_2_9_140_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(08)62536-4"},{"key":"e_1_2_9_141_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1323816111"},{"issue":"4","key":"e_1_2_9_142_1","doi-asserted-by":"crossref","first-page":"515","DOI":"10.55782\/ane-2000-1373","article-title":"Brain injury: prolonged induction of transcription factors","volume":"60","author":"Pennypacker KR","year":"2000","journal-title":"Acta Neurobiol Exp (Wars)"},{"key":"e_1_2_9_143_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhm124"},{"key":"e_1_2_9_144_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhn078"},{"key":"e_1_2_9_145_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1105108108"},{"key":"e_1_2_9_146_1","doi-asserted-by":"publisher","DOI":"10.1111\/bpa.12096"},{"key":"e_1_2_9_147_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2018.00025"},{"key":"e_1_2_9_148_1","first-page":"82","article-title":"The complexity of the calretinin expressing progenitors in the human cerebral cortex","volume":"8","author":"Radonjic NV","year":"2014","journal-title":"Front Neuroanat"},{"key":"e_1_2_9_149_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.1977.0040"},{"key":"e_1_2_9_150_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/13.6.541"},{"key":"e_1_2_9_151_1","doi-asserted-by":"crossref","DOI":"10.5962\/bhl.title.48637","volume-title":"Histologie du syst\u00e8me nerveux de l'homme & des vert\u00e9br\u00e9s","author":"Ram\u00f3n y Cajal S","year":"1909"},{"key":"e_1_2_9_152_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhr284"},{"key":"e_1_2_9_153_1","doi-asserted-by":"publisher","DOI":"10.1159\/000071021"},{"key":"e_1_2_9_154_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2004.00261.x"},{"key":"e_1_2_9_155_1","doi-asserted-by":"publisher","DOI":"10.4067\/S0716-97602012000300005"},{"key":"e_1_2_9_156_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2019"},{"key":"e_1_2_9_157_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00300010"},{"key":"e_1_2_9_158_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhx358"},{"key":"e_1_2_9_159_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhy205"},{"key":"e_1_2_9_160_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhq035"},{"key":"e_1_2_9_161_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2005.09.005"},{"key":"e_1_2_9_162_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2015.00411"},{"key":"e_1_2_9_163_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.274.5290.1123"},{"key":"e_1_2_9_164_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1538-11.2012"},{"issue":"3","key":"e_1_2_9_165_1","first-page":"771","article-title":"Transient structures of the human fetal brain: subplate, thalamic reticular complex, ganglionic eminence","volume":"15","author":"Ulfig N","year":"2000","journal-title":"Histol Histopathol"},{"key":"e_1_2_9_166_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2010.01260.x"},{"key":"e_1_2_9_167_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnana.2016.00011"},{"key":"e_1_2_9_168_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2017.00348"},{"key":"e_1_2_9_169_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0029(19990701)46:1<24::AID-JEMT3>3.0.CO;2-E"},{"key":"e_1_2_9_170_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903360303"},{"issue":"1","key":"e_1_2_9_171_1","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1542\/peds.97.1.112","article-title":"Subplate neurons \u2013 missing link in brain injury of the premature infant?","volume":"97","author":"Volpe JJ","year":"1996","journal-title":"Pediatrics"},{"key":"e_1_2_9_172_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(08)70294-1"},{"key":"e_1_2_9_173_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2010.01274.x"},{"key":"e_1_2_9_174_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnana.2015.00147"},{"key":"e_1_2_9_175_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2012.00120"},{"key":"e_1_2_9_176_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20044"},{"key":"e_1_2_9_177_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.20714"},{"key":"e_1_2_9_178_1","doi-asserted-by":"publisher","DOI":"10.1002\/dneu.20812"},{"key":"e_1_2_9_179_1","doi-asserted-by":"crossref","DOI":"10.1007\/s00429-018-1721-2","article-title":"Interactive histogenesis of axonal strata and proliferative zones in the human fetal cerebral wall","author":"\u017duni\u0107 I\u0161asegi II","year":"2018","journal-title":"Brain Struct Funct"}],"container-title":["Journal of Anatomy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joa.12920","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/joa.12920","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joa.12920","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T13:06:45Z","timestamp":1775308005000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joa.12920"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,13]]},"references-count":178,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["10.1111\/joa.12920"],"URL":"https:\/\/doi.org\/10.1111\/joa.12920","archive":["Portico"],"relation":{},"ISSN":["0021-8782","1469-7580"],"issn-type":[{"value":"0021-8782","type":"print"},{"value":"1469-7580","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,13]]},"assertion":[{"value":"2018-11-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}