{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:28:16Z","timestamp":1787498896413,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,10,27]],"date-time":"2019-10-27T00:00:00Z","timestamp":1572134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005630","name":"Soci\u00e9t\u00e9 Fran\u00e7aise de Cardiologie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005630","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Anatomy"],"published-print":{"date-parts":[[2020,2]]},"abstract":"Abstract<\/jats:title>\n \n Congenitally corrected transposition of the great arteries (cc\n TGA<\/jats:styled-content>\n ) is a rare congenital malformation which associates discordant atrioventricular and ventriculo\u2010arterial connections. Although frequently associated with a ventricular septal defect (\n VSD<\/jats:styled-content>\n ), its anatomy remains controversial. This could be due in hearts with usual atrial arrangement to the apparently different anatomy of the left\u2010sided right ventricle compared with a right\u2010sided right ventricle. We wanted to compare the\n RV<\/jats:styled-content>\n septal anatomy between cc\n TGA<\/jats:styled-content>\n , transposition of the great arteries and normal heart and to determine the anatomy of the\n VSD<\/jats:styled-content>\n in cc\n TGA<\/jats:styled-content>\n . We analysed 102 human heart specimens: 31 cc\n TGA<\/jats:styled-content>\n , 36 transpositions of the great arteries, 35 normal hearts. According to the last classification of\n VSD<\/jats:styled-content>\n (\n ICD<\/jats:styled-content>\n \u201011),\n VSD<\/jats:styled-content>\n were classified as outlet if located above the superoseptal\u00a0commissure of the tricuspid valve and inlet if underneath. We measured the lengths of the superior and inferior limbs of the septal band and the angle between the two limbs. To assess the orientation of the septal band, we also measured the angle between superior limb and the arterial valve above. A\n VSD<\/jats:styled-content>\n was present in 26 cc\n TGA<\/jats:styled-content>\n (84%) and was an outlet\n VSD<\/jats:styled-content>\n in 16 cases (61%). The mean angle between the two limbs of the septal band was 76.4\u00b0 for cc\n TGA<\/jats:styled-content>\n compared with 90.6\u00b0 for transposition of the great arteries (\n P<\/jats:italic>\n \u00a0=\u00a00.011) and 76.1\u00b0 for normal hearts (\n P<\/jats:italic>\n = NS). The mean angle between the superior limb of the septal band and the arterial valve above was 70.6\u00b0 for cc\n TGA<\/jats:styled-content>\n compared with 90.6\u00b0 for transposition of the great arteries (\n P<\/jats:italic>\n \u00a0=\u00a00.0004) and 69.1\u00b0 for normal hearts (\n P= NS<\/jats:italic>\n ). The inferior limb of the septal band was significantly shorter in cc\n TGA<\/jats:styled-content>\n (\n P<\/jats:italic>\n \u00a0<\u00a00.0003):\n SL<\/jats:styled-content>\n \/\n IL<\/jats:styled-content>\n length ratio was 21.4 for cc\n TGA<\/jats:styled-content>\n , 2.2 for transposition of the great arteries and 1.5 for normal hearts. The typical\n VSD<\/jats:styled-content>\n in cc\n TGA<\/jats:styled-content>\n is an outlet\n VSD<\/jats:styled-content>\n . Its frequent misdiagnosis as an inlet\n VSD<\/jats:styled-content>\n might be explained by the shortness of the inferior limb, which creates the illusion of a posterior\n VSD<\/jats:styled-content>\n , and by the fact that the\n VSD<\/jats:styled-content>\n is usually assessed from the left ventricular aspect. Surprisingly, the orientation of the septal band is similar in cc\n TGA<\/jats:styled-content>\n and normal heart, despite the discordant atrioventricular connections, and different in cc\n TGA<\/jats:styled-content>\n and transposition of the great arteries, despite the discordant ventriculo\u2010arterial connections. These findings suggest that the mechanism leading to transposition in cc\n TGA<\/jats:styled-content>\n and in\n TGA<\/jats:styled-content>\n probably is different. The term \u2018double discordance\u2019 might therefore be more appropriate as a description of this complex anomaly.\n <\/jats:p>","DOI":"10.1111\/joa.13097","type":"journal-article","created":{"date-parts":[[2019,10,28]],"date-time":"2019-10-28T01:15:36Z","timestamp":1572225336000},"page":"325-333","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Congenitally corrected transposition of the great arteries: is it really a transposition? An anatomical study of the right ventricular septal surface"],"prefix":"10.1111","volume":"236","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8075-8481","authenticated-orcid":false,"given":"Nicolas","family":"Arribard","sequence":"first","affiliation":[{"name":"Laboratory of Anatomy of Congenital Heart Disease \u2010 M3C H\u00f4pital Marie Lannelongue Le Plessis\u2010Robinson France"},{"name":"Laboratory of Surgical Research INSERM U999 H\u00f4pital Marie Lannelongue Le Plessis Robinson France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9143-9366","authenticated-orcid":false,"given":"Meriem","family":"Mostefa Kara","sequence":"additional","affiliation":[{"name":"Laboratory of Anatomy of Congenital Heart Disease \u2010 M3C H\u00f4pital Marie Lannelongue Le Plessis\u2010Robinson France"},{"name":"Medico\u2010surgical Unit, Congenital and Paediatric Cardiology Centre de R\u00e9f\u00e9rence Malformations Cardiaques Cong\u00e9nitales Complexes \u2010 M3C H\u00f4pital Marie Lannelongue Le Plessis Robinson France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8695-0503","authenticated-orcid":false,"given":"S\u00e9bastien","family":"Hasco\u00ebt","sequence":"additional","affiliation":[{"name":"Laboratory of Surgical Research INSERM U999 H\u00f4pital Marie Lannelongue Le Plessis Robinson France"},{"name":"Medico\u2010surgical Unit, Congenital and Paediatric Cardiology Centre de R\u00e9f\u00e9rence Malformations Cardiaques Cong\u00e9nitales Complexes \u2010 M3C H\u00f4pital Marie Lannelongue Le Plessis Robinson France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina","family":"Bessi\u00e8res","sequence":"additional","affiliation":[{"name":"Fetal Pathology Department H\u00f4pital Necker Enfants Malades APHP Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damien","family":"Bonnet","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Descartes Sorbonne Paris Cit\u00e9 Paris France"},{"name":"Medico\u2010surgical Unit, Congenital and Paediatric Cardiology Centre de R\u00e9f\u00e9rence Malformations Cardiaques Cong\u00e9nitales Complexes \u2010 M3C H\u00f4pital Necker Enfants Malades, APHP France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucile","family":"Houyel","sequence":"additional","affiliation":[{"name":"Laboratory of Anatomy of Congenital Heart Disease \u2010 M3C H\u00f4pital Marie Lannelongue Le Plessis\u2010Robinson France"},{"name":"Universit\u00e9 Paris Descartes Sorbonne Paris Cit\u00e9 Paris France"},{"name":"Medico\u2010surgical Unit, Congenital and Paediatric Cardiology Centre de R\u00e9f\u00e9rence Malformations Cardiaques Cong\u00e9nitales Complexes \u2010 M3C H\u00f4pital Necker Enfants Malades, APHP 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