{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T16:55:53Z","timestamp":1787936153164,"version":"build-2784847793"},"reference-count":50,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,3,11]],"date-time":"2020-03-11T00:00:00Z","timestamp":1583884800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Anatomy"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In spite of the amount of research on fetal development of the human middle ear and ear ossicles, there has been no report showing a joint between the short limb of incus and the otic capsule or petrous part of the temporal bone. According to observations of serial histological sections from 65 embryos and fetuses at 7\u201317\u00a0weeks of development, the incudopetrosal joint exhibited a developmental sequence similar to the other joints of ossicles, with an appearance of an interzone followed by a trilaminar configuration at 7\u201312\u00a0weeks, a joint cavitation at 13\u201315\u00a0weeks and development of intraarticular and capsular ligaments at 16\u201317\u00a0weeks. These processes occurred at the same time or slightly later than any other joint. Thus, the joint development might coordinate with vibrating ossicles <jats:italic>in utero<\/jats:italic>. The growing short limb of incus appeared to accelerate an expansion of the epitympanic recess of the tympanic cavity. Additional observations of five late\u2010stage fetuses demonstrated the incudopetrosal joint located in the fossa incudis joint changing to syndesmosis. Consequently, a real joint with a cavity existed transiently between the human neurocranium and the first pharyngeal arch derivative (i.e. incus) in contrast to the tympanostapedial joint or syndesmosis between the neurocranium and the second arch derivative. The newly described joint might have an effect on the widely accepted primary jaw concept: the mammalian jaw should thus have been created within the first pharyngeal arch, although the connection with neurocranium by the stapes is of a different origin.<\/jats:p>","DOI":"10.1111\/joa.13181","type":"journal-article","created":{"date-parts":[[2020,3,11]],"date-time":"2020-03-11T09:10:46Z","timestamp":1583917846000},"page":"176-187","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["The incudopetrosal joint of the human middle ear: a transient morphology in fetuses"],"prefix":"10.1111","volume":"237","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5423-4492","authenticated-orcid":false,"given":"Jos\u00e9 Francisco","family":"Rodr\u00edguez\u2010V\u00e1zquez","sequence":"first","affiliation":[{"name":"Department of Anatomy and Embryology Institute of Embryology School of Medicine Complutense University Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9683-6678","authenticated-orcid":false,"given":"Masahito","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Anatomy Tokyo Dental College Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Hyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Institute of Medical Science Chonbuk National University Medical School Jeonju Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe\u2010Wu","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Anatomy Wuxi Medical School Jiangnan University Wuxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukio","family":"Katori","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Tohoku University Graduate School of Medicine Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gen","family":"Murakami","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine Jikoukai Home Visits Clinic Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,3,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1971.00770070799004"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.1978.88.7.1067"},{"key":"e_1_2_8_4_1","volume-title":"Surgical anatomy of the temporal bone and ear","author":"Anson B.J.","year":"1973"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348946006900212"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100107947"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/joa.12520"},{"key":"e_1_2_8_8_1","first-page":"269","article-title":"Contribuci\u00f3n al conocimiento morfol\u00f3gico de las articulaciones de la cadena osicular timp\u00e1nica humana","volume":"48","author":"Castellote A.","year":"1997","journal-title":"Acta Otorrinolaringol\u00f3gica Espa\u00f1ola"},{"key":"e_1_2_8_9_1","first-page":"76","article-title":"Congenital ossicular malformations: a review of 68 cases","volume":"9","author":"Cousins V.C.","year":"1988","journal-title":"American Journal of Otology"},{"key":"e_1_2_8_10_1","first-page":"61","article-title":"The recesses of the retro\u2010tympanum","volume":"51","author":"Chei\u0163\u0103 A.C.","year":"2010","journal-title":"Romanian Journal of Morphology and Embryology"},{"key":"e_1_2_8_11_1","first-page":"1","article-title":"Die Reichertsche Theorie","volume":"1912","author":"Gaupp E.","year":"1913","journal-title":"Archiv f\u00fcr Anatomie, Physiologie und Wissenschaftliche Medicin (Suppl.)"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.5962\/bhl.title.82144"},{"key":"e_1_2_8_13_1","volume-title":"Embriolog\u00eda Humana","author":"Hamilton W.I.","year":"1975"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02885012"},{"key":"e_1_2_8_15_1","first-page":"358","article-title":"The early embryology of the auditory ossicles in man","volume":"33","author":"Hanson J.R.","year":"1959","journal-title":"Quarterly Bulletin of the Northwestern University Medical School"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1962.00740050208004"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1963.00750020345016"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2012.01542.x"},{"key":"e_1_2_8_19_1","first-page":"1","article-title":"Die Entwicklung und Morphologie des Sch\u00e4dels von Tachyglossus aculeatus","volume":"528","author":"Kuhn H.J.","year":"1971","journal-title":"Abh Senckenbergischen Natur Gesell"},{"key":"e_1_2_8_20_1","first-page":"29","article-title":"Le d\u00e9veloppement des osselets de l\u00b4ou\u00efe chez l\u00b4embryon humain: corr\u00e9lations avec les donn\u00e9es recueillies chez la souris","volume":"236","author":"Louryan S.","year":"1993","journal-title":"Bulletin de l'Association des Anatomistes"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.morpho.2018.09.002"},{"key":"e_1_2_8_22_1","first-page":"123","article-title":"Der Processus angularis bei Monodelphis domestica (Didelphidae, Marsupialia) und seine Beziehungen zum Mittelohr: Eine ontogenetische und evolutionsmorphologische Untersuchung","volume":"133","author":"Maier W.","year":"1987","journal-title":"Gegenbaurs Morphologisches Jahrbuch"},{"key":"e_1_2_8_23_1","first-page":"109","article-title":"Histological development of stapes footplate in human embryos","volume":"32","author":"Masuda Y.","year":"1978","journal-title":"Acta Medica Okayama"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001510403"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198804000-00006"},{"key":"e_1_2_8_26_1","volume-title":"Human Embryology and Teratology","author":"O\u2019Rahilly R.","year":"1996"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1159\/000289817"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.23457"},{"key":"e_1_2_8_29_1","first-page":"505","article-title":"Epitympanic compartment surgical considerations: Reevaluation","volume":"16","author":"Palva T.","year":"1995","journal-title":"American Journal of Otology"},{"key":"e_1_2_8_30_1","first-page":"700","article-title":"Incudal folds and epitympanic aeration","volume":"17","author":"Palva T.","year":"1996","journal-title":"American Journal of Otology"},{"key":"e_1_2_8_31_1","first-page":"512","article-title":"Prussak's space revisited","volume":"17","author":"Palva T.","year":"1996","journal-title":"American Journal of Otology"},{"key":"e_1_2_8_32_1","volume-title":"Einf\u00fchrung in die vergleichende Morphologie der Wirbeltiere","author":"Portmann A.","year":"1969"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1017\/S002221510006254X"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1159\/000147188"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1092330312"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2005.00441.x"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2009.01105.x"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2011.01378.x"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aanat.2016.09.001"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.23832"},{"key":"e_1_2_8_41_1","volume-title":"Gray\u2019s anatomy","author":"Standring S.","year":"2005"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1962.00740050106003"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aanat.2013.03.010"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.b.21347"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0385-8146(96)80002-2"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.23831"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1063830"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1159\/000063124"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0264.2008.00888.x"},{"key":"e_1_2_8_50_1","volume-title":"Gray\u2019s Anatomy","author":"Williams P.L.","year":"1995"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.281053"}],"container-title":["Journal of Anatomy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjoa.13181","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joa.13181","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/joa.13181","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joa.13181","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T23:41:09Z","timestamp":1693957269000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joa.13181"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,11]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1111\/joa.13181"],"URL":"https:\/\/doi.org\/10.1111\/joa.13181","archive":["Portico"],"relation":{},"ISSN":["0021-8782","1469-7580"],"issn-type":[{"value":"0021-8782","type":"print"},{"value":"1469-7580","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,11]]},"assertion":[{"value":"2019-11-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-02-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}