{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:51:51Z","timestamp":1772160711391,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,8,2]],"date-time":"2023-08-02T00:00:00Z","timestamp":1690934400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Anatomy"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Dextrocardia is a rare congenital malformation in humans in which most of the heart mass is positioned in the right hemithorax rather than on the left. The heart itself may be normal and dextrocardia is sometimes diagnosed during non\u2010related explorations. A few reports have documented atypical positions of the cardiac chambers in farmed teleost fish. Here, we report the casual finding of a left\u2013right mirrored heart in an 85\u2009cm long wild\u2010caught spiny dogfish (\n                    <jats:italic>Squalus acanthias<\/jats:italic>\n                    ) with several organ malformations. Macroscopic observations showed an outflow tract originating from the left side of the ventricular mass, rather than from the right. Internal inspection revealed the expected structures and a looped cavity. The inner curvature of the loop comprised a large trabeculation, the bulboventricular fold, as expected. The junction between the sinus venosus and the atrium appeared normal, only mirrored. MRI data acquired at 0.7\u2009mm isotropic resolution and subsequent 3D\u2010modeling revealed the atrioventricular canal was to the right of the bulboventricular fold, rather than on the left. Spurred by the finding of dextrocardia in the shark, we revisit our previously published material on farmed Adriatic sturgeon (\n                    <jats:italic>Acipenser naccarii<\/jats:italic>\n                    ), a non\u2010teleost bony fish. We found several alevins with inverted (left\u2010loop) hearts, amounting to an approximate incidence of 1%\u20132%. Additionally, an adult sturgeon measuring 90\u2009cm in length showed abnormal topology of the cardiac chambers, but normal position of the abdominal organs. In conclusion, left\u2013right mirrored hearts, a setting that resembles human dextrocardia, can occur in both farmed and wild non\u2010teleost fish.\n                  <\/jats:p>","DOI":"10.1111\/joa.13933","type":"journal-article","created":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T02:10:52Z","timestamp":1691028652000},"page":"1052-1058","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Laterality defect of the heart in non\u2010teleost fish"],"prefix":"10.1111","volume":"243","author":[{"given":"Myrte M.","family":"Huijskes","sequence":"first","affiliation":[{"name":"Department of Medical Biology, Amsterdam Cardiovascular Sciences University of Amsterdam, Amsterdam UMC  Amsterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 M.","family":"Icardo","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Cell Biology University of Cantabria  Santander Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bram F.","family":"Coolen","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering and Physics, Amsterdam Cardiovascular Sciences University of Amsterdam, Amsterdam UMC  Amsterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7750-8035","authenticated-orcid":false,"given":"Bjarke","family":"Jensen","sequence":"additional","affiliation":[{"name":"Department of Medical Biology, Amsterdam Cardiovascular Sciences University of Amsterdam, Amsterdam UMC  Amsterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,8,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001090105"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.02.095"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aag0053"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2020.735615"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0185(199706)248:2<224::AID-AR9>3.0.CO;2-S"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.46.2.375"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1095-8649.2008.02125.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.23902"},{"issue":"8","key":"e_1_2_6_10_1","first-page":"900","article-title":"Conus arteriosus of the teleost heart: dismissed, but not missed","volume":"288","author":"Icardo J.M.","year":"2006","journal-title":"The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology: An Official Publication of the American Association of Anatomists"},{"key":"e_1_2_6_11_1","first-page":"1","volume-title":"Fish physiology","author":"Icardo J.M.","year":"2017"},{"issue":"1","key":"e_1_2_6_12_1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/ar.10080","article-title":"Structure of the conus arteriosus of the sturgeon (Acipenser naccarii) heart. I: the conus valves and the subendocardium","volume":"267","author":"Icardo J.M.","year":"2002","journal-title":"The Anatomical Record: An Official Publication of the American Association of Anatomists"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.20939"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-004-0418-x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0063651"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/brv.12411"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms3754"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4020-8437-9_7"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.156.1.387"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.3354\/dao050153"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1092170307"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcdd8060064"},{"key":"e_1_2_6_23_1","first-page":"459","volume-title":"Congenital heart disease: Causes and processes","author":"Van Mierop L.H.S.","year":"1984"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.12-218073"}],"container-title":["Journal of Anatomy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joa.13933","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T22:30:25Z","timestamp":1699828225000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joa.13933"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,2]]},"references-count":23,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["10.1111\/joa.13933"],"URL":"https:\/\/doi.org\/10.1111\/joa.13933","archive":["Portico"],"relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2023.06.13.544822","asserted-by":"object"}]},"ISSN":["0021-8782","1469-7580"],"issn-type":[{"value":"0021-8782","type":"print"},{"value":"1469-7580","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,2]]},"assertion":[{"value":"2023-06-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}