{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T02:22:55Z","timestamp":1788056575029,"version":"build-2784847793"},"reference-count":43,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:00:00Z","timestamp":1763078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:00:00Z","timestamp":1763078400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP 22K17645"],"award-info":[{"award-number":["JP 22K17645"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Anatomy"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The sacroiliac joint allows limited but crucial movement for transmitting loads from the spine to the pelvis. Identifying anatomical structures that adapt to this motion may improve imaging\u2010based diagnosis of sacroiliac joint dysfunction. The interosseous sacroiliac ligament (ISIL), a key stabilizer connecting the sacrum and ilium, has unclear adaptive responses to mechanical stress. This study aimed to investigate the ISIL's gross morphology, fiber orientation, and histological features. A total of 11 hemipelves from eight donors were examined, six for gross anatomy and five for histology. Fiber orientation was evaluated using micro\u2010computed tomography. The distribution of fiber angles was compared between the superior and inferior ISIL regions, ranging from +90\u00b0 (vertical) to \u221290\u00b0, using paired t\u2010tests with statistical parametric mapping. The ISIL displayed a consistent fibrous architecture, with predominantly vertical fibers in the inferior region and a higher frequency of horizontal fibers in the superior region. Orientation analysis revealed more vertical fibers (70\u00b0\u201380\u00b0) inferiorly and more horizontal fibers (\u221250\u00b0 to \u221230\u00b0) superiorly (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). Histology confirmed these findings and revealed a synovial bursa\u2010like structure between the ISIL and the posteroinferior sacrum. These findings suggest that the ISIL exhibits region\u2010specific fiber alignment, with vertical fibers inferiorly and horizontal fibers superiorly, along with a synovial bursa\u2010like structure adjacent to the sacrum. These patterns likely reflect mechanical adaptation to sacroiliac joint motion and may guide imaging\u2010based assessment of sacroiliac joint dysfunction. Our suggestion requires validation based on the direct mechanical data through biomechanical and clinical research, and the limitation of quantitative analysis being 2D and having a small sample size need to be addressed in future studies incorporating in\u00a0vivo 3D imaging.\n                  <\/jats:p>","DOI":"10.1111\/joa.70077","type":"journal-article","created":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T16:57:27Z","timestamp":1763139447000},"page":"68-77","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Significance of fiber orientation in the interosseous sacroiliac ligament: An anatomical and histological study of the implications of its mechanical adaptation"],"prefix":"10.1111","volume":"249","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1803-8202","authenticated-orcid":false,"given":"Masahiro","family":"Tsutsumi","sequence":"first","affiliation":[{"name":"Inclusive Medical Sciences Research Institute Morinomiya University of Medical Sciences  Osaka City Osaka Japan"},{"name":"Department of Clinical Anatomy Institute of Science Tokyo  Bunkyo\u2010ku Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akimoto","family":"Nimura","sequence":"additional","affiliation":[{"name":"Department of Functional Joint Anatomy Institute of Science Tokyo  Bunkyo\u2010ku Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajime","family":"Utsunomiya","sequence":"additional","affiliation":[{"name":"Tokyo Research Institute for Sports Medicine  Kisarazu\u2010shi Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Ibara","sequence":"additional","affiliation":[{"name":"Department of Functional Joint Anatomy Institute of Science Tokyo  Bunkyo\u2010ku Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shintarou","family":"Kudo","sequence":"additional","affiliation":[{"name":"Inclusive Medical Sciences Research Institute Morinomiya University of Medical Sciences  Osaka City Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiichi","family":"Akita","sequence":"additional","affiliation":[{"name":"Department of Clinical Anatomy Institute of Science Tokyo  Bunkyo\u2010ku Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0278\u20105919(02)00026\u20101"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0954411920978021"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000180831.60169.ea"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1586\/ern.12.148"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/23259671211049457"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100034\u20101375574"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/joa.12924"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2013.03.050"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/joa.14160"},{"key":"e_1_2_9_11_1","volume-title":"The Physiology of the Joints","author":"Kapandji I.A.","year":"2019"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010018\u201035425\u20100"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200112000-00006"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2017.12.017"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.20.2.g00mc09333"},{"key":"e_1_2_9_16_1","first-page":"1352","volume-title":"Gray's anatomy: the anatomical basis of clinical practice","author":"Neumann D.A.","year":"2021"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v071.i07"},{"issue":"8","key":"e_1_2_9_18_1","first-page":"252","article-title":"A method for quick decalcification","volume":"89","author":"Plank J.","year":"1952","journal-title":"Zentralblatt Fur Allgemeine Pathologie u. 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