{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T10:28:54Z","timestamp":1790504934103,"version":"4.1.0"},"reference-count":43,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,2,26]],"date-time":"2013-02-26T00:00:00Z","timestamp":1361836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:label\/><jats:p>Both vitiligo and alopecia areata (<jats:styled-content style=\"fixed-case\">AA<\/jats:styled-content>) are associated together, associated with other autoimmune diseases, and autoimmunity is one of the important theories in their etiology. Nail changes are a known association with <jats:styled-content style=\"fixed-case\">AA<\/jats:styled-content>, thus we hypothesized that nail changes can be found in vitiligo patients. On revising the literature, only two types of nail changes were described in association with vitiligo. Our aim was to study the frequency and types of nail changes among vitiligo patients in comparison with normal healthy volunteers. This multi\u2010centric study was carried on 91 patients with vitiligo, as well as 91 normal healthy control subjects who were age\u2010 and sex\u2010matched. Nails were examined for changes in nail plates as regards striations, texture, curvature, dystrophy, and pigmentation. The presence or absence of the thumb lunula was also reported. Nail changes were observed in 62 patients (68.1%) and 46 (50.5%) control subjects with a statistically significant difference (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.016). Longitudinal ridging and absent lunula were significantly higher in patients than in the controls (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.001 and 0.037, respectively). Other reported nail abnormalities in the current study included punctate leukonychia, pitting, flag sign, and <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>erry's nails. Awareness of this association will widen the clinician's perspective to carefully examine the nail changes in vitiligo patients and conversely examine patients with nail changes for vitiligo.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.12022","type":"journal-article","created":{"date-parts":[[2013,2,26]],"date-time":"2013-02-26T09:45:33Z","timestamp":1361871933000},"page":"67-72","source":"Crossref","is-referenced-by-count":12,"title":["Clinical study of nail changes in vitiligo"],"prefix":"10.1111","volume":"12","author":[{"given":"Tag","family":"Anbar","sequence":"first","affiliation":[{"name":"Dermatology Department Al\u2010Minya University Al\u2010Minya Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rania Abdel","family":"Hay","sequence":"additional","affiliation":[{"name":"Dermatology Department Cairo University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amal T","family":"Abdel\u2010Rahman","sequence":"additional","affiliation":[{"name":"Dermatology Department Al\u2010Minya University Al\u2010Minya Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noha H","family":"Moftah","sequence":"additional","affiliation":[{"name":"Dermatology Department Al\u2010Minya University Al\u2010Minya Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed A","family":"Al\u2010Khayyat","sequence":"additional","affiliation":[{"name":"Dermatology Department Al\u2010Minya University Al\u2010Minya Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,2,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1529-8019.2001.01036.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1529-8019.2002.01511.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sder.2009.04.008"},{"key":"e_1_2_5_5_1","first-page":"893","volume-title":"Fitzpatrick's Dermatology in General Medicine","author":"Ortonne JP","year":"2003"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0749.2003.00032.x"},{"key":"e_1_2_5_7_1","first-page":"68","article-title":"High frequency of thyroid dysfunction in Indian patients with vitiligo","volume":"48","author":"Dave S","year":"2003","journal-title":"Indian J 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