{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T02:49:00Z","timestamp":1787366940559,"version":"build-2736575974"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,12,4]],"date-time":"2013-12-04T00:00:00Z","timestamp":1386115200000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2013,12]]},"abstract":"Summary<\/jats:title>\n \n Introduction<\/jats:title>\n \n The addition of hydrophobically modified polymers (\n HMP<\/jats:styled-content>\n s) to cleansers that contain surfactants can create polymer\u2013surfactant complexes that are less irritating to the skin than commercially available mild cleansers. Our objective was to compare the tolerability and efficacy of a test foaming liquid facial cleanser containing\n HMP<\/jats:styled-content>\n s with a commercial liquid nonfoaming facial cleanser in women with sensitive skin.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n In this randomized, prospective, double\u2010blind, comparative study, women (\n n<\/jats:italic>\n \u00a0=\u00a020 per group) with mild\u2010to\u2010moderate atopic dermatitis (\n AD<\/jats:styled-content>\n ), eczema, acne, or rosacea used a test gentle foaming liquid facial cleanser containing\n HMP<\/jats:styled-content>\n s or a commercial gentle liquid nonfoaming facial cleanser daily for 3\u00a0weeks. Investigators assessed irritation and skin condition. Study subjects also assessed their skin properties and the performance of each cleanser.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Clinicians as well as study subjects consistently rated the test cleanser as effective or slightly more effective at improving symptoms than the commercial cleanser, although no significant differences between groups were observed. At weeks 1 and 3, respectively, more users of the commercial cleanser reported irritation (20% and 10%) than users of the test cleanser (5% and 5%). In addition, subject self\u2010assessments of skin condition and cleansing properties were slightly more improved with the test cleanser than with the commercial cleanser.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Both the test foaming cleanser containing\n HMP<\/jats:styled-content>\n s and the commercial nonfoaming cleanser were effective and well accepted by most women in the study. Improvements were observed by both clinicians and subjects in the group using the test cleanser containing\n HMP<\/jats:styled-content>\n s in all evaluated skin categories.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jocd.12061","type":"journal-article","created":{"date-parts":[[2013,12,4]],"date-time":"2013-12-04T10:00:05Z","timestamp":1386151205000},"page":"314-321","source":"Crossref","is-referenced-by-count":43,"title":["Hydrophobically modified polymers can minimize skin irritation potential caused by surfactant\u2010based cleansers"],"prefix":"10.1111","volume":"12","author":[{"given":"Zoe","family":"Draelos","sequence":"first","affiliation":[{"name":"Dermatology Consulting Services High Point NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sidney","family":"Hornby","sequence":"additional","affiliation":[{"name":"Johnson & Johnson Consumer Companies, Inc. Skillman NJ USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russel M","family":"Walters","sequence":"additional","affiliation":[{"name":"Johnson & Johnson Consumer Companies, Inc. Skillman NJ USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohini","family":"Appa","sequence":"additional","affiliation":[{"name":"Johnson & Johnson Consumer Companies, Inc. Skillman NJ USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,12,4]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/495917"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1396-0296.2004.04S1004.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1396-0296.2004.04S1002.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2003.480105.x"},{"key":"e_1_2_5_6_1","first-page":"143","article-title":"Penetration of mixed micelles into the epidermis: effect of mixing sodium dodecyl sulfate with dodecyl hexa(ethylene oxide)","volume":"54","author":"Moore PN","year":"2003","journal-title":"J Cosmet Sci"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00424272"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2494.2011.00678.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-012-0748-y"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0846.2007.00242.x"},{"key":"e_1_2_5_11_1","first-page":"22","article-title":"The clinical relevance of maintaining the functional integrity of the stratum corneum in both healthy and disease\u2010affected skin","volume":"4","author":"Rosso JQ","year":"2011","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1467-2494.2003.00176.x"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000245955"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0022-202x.2001.01399.x"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2002.01555.x"},{"key":"e_1_2_5_16_1","first-page":"697","article-title":"Polymer\u2010surfactant self\u2010assembly for the design of mild skin cleansers","volume":"52","author":"Walters RM","year":"2011","journal-title":"Polymer Prepr"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1021\/bk-2010-1053.ch012"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12365467"},{"key":"e_1_2_5_19_1","first-page":"177","volume-title":"Surfactants in Personal Care and Decorative Cosmetics","author":"Lips A","year":"2007"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjocd.12061","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.12061","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.12061","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.12061","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T04:15:54Z","timestamp":1696220154000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.12061"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["10.1111\/jocd.12061"],"URL":"https:\/\/doi.org\/10.1111\/jocd.12061","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12]]}}}