{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T06:11:55Z","timestamp":1761718315885},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,6,9]],"date-time":"2014-06-09T00:00:00Z","timestamp":1402272000000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cleansing products for acne should remove excessive sebum, reduce acne\u2010related bacteria and improve inflammation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>The aim of the study was to investigate a topical cleansing product containing glycolic acid with pH 4 in mild acne vulgaris.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixty patients were recruited for this open uncontrolled clinical trial. The tested product was exclusively applied twice a day for 6\u00a0weeks. The efficacy was judged by a dermatologist according to the Leeds score after 3 and 6\u00a0weeks. In addition, efficacy and tolerability were judged subjectively by physician and patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mild acne improved significantly after 6 weeks (baseline: 0.699 <jats:italic>vs<\/jats:italic>. day 42: 0.602; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). Efficacy and tolerability were judged better by physician as compared with patients' assessment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this clinical trial, a topical cleansing product containing glycolic acid with pH 4 improved mild acne significantly following twice\u2010daily application for 6\u00a0weeks as monotherapy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.12086","type":"journal-article","created":{"date-parts":[[2014,6,9]],"date-time":"2014-06-09T10:30:00Z","timestamp":1402309800000},"page":"103-108","source":"Crossref","is-referenced-by-count":9,"title":["Significant improvement in mild acne following a twice daily application for 6\u00a0weeks of an acidic cleansing product (pH 4)"],"prefix":"10.1111","volume":"13","author":[{"given":"Christoph","family":"Abels","sequence":"first","affiliation":[{"name":"Dr. August Wolff GmbH &amp; Co. KG Arzneimittel Bielefeld Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hubert","family":"Reich","sequence":"additional","affiliation":[{"name":"Dr. August Wolff GmbH &amp; Co. KG Arzneimittel Bielefeld Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich","family":"Knie","sequence":"additional","affiliation":[{"name":"Dr. August Wolff GmbH &amp; Co. KG Arzneimittel Bielefeld Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dieter","family":"Werdier","sequence":"additional","affiliation":[{"name":"SAM GmbH Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunter","family":"Lemmnitz","sequence":"additional","affiliation":[{"name":"Dr. August Wolff GmbH &amp; Co. 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