{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T12:41:49Z","timestamp":1760013709020},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,11,17]],"date-time":"2014-11-17T00:00:00Z","timestamp":1416182400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The nail unit is an important part of cosmetic appearance of an individual. Older people are at an increased risk of nail alterations, including normal age\u2010related changes and disorders that more commonly affect this specific population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To identify and evaluate the age\u2010related nail changes and disorders in Egyptian elderly people both clinically and histopathologically.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients\/Methods<\/jats:title><jats:p>A total of 400 adult subjects, not complaining from any dermatological disease, were included in the present study; half of them were elderly of 60\u00a0years and above (elderly group). Meanwhile, the other half served as a control group with younger ages. Full history taking, general and local examinations as well as nail biopsies were performed from selected cases with age\u2010related nail changes and disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Nail changes were significantly (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05) more common in old age group (88%) compared to control subjects (39%). The commonest age\u2010related nail changes noticed were pale, dull, opaque, and lusterless nails (73%); brittle nails (67.5%); decreased lunula visibility (49%); and onychorrhexis (45.5%). They showed highly significant increase (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) when compared with control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The prevalence of nail changes and disorders has increased among elderly patients although they are frequently overlooked by health care providers. Dermatologist should be aware about various nail changes related to aging and those associated with other dermatoses or systemic diseases. Histopathologic picture can enhance the accuracy of clinical diagnosis of various nail changes and disorders.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.12113","type":"journal-article","created":{"date-parts":[[2014,11,17]],"date-time":"2014-11-17T05:26:21Z","timestamp":1416201981000},"page":"269-276","source":"Crossref","is-referenced-by-count":11,"title":["Nail changes and disorders in elderly Egyptians"],"prefix":"10.1111","volume":"13","author":[{"given":"Moetaz","family":"El\u2010Domyati","sequence":"first","affiliation":[{"name":"Department of Dermatology Faculty of Medicine Al\u2010Minya University Al\u2010Minya Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hossam","family":"Abdel\u2010Wahab","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty of Medicine Al\u2010Minya University Al\u2010Minya Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eman","family":"Abdel\u2010Azim","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty of Medicine Al\u2010Minya University Al\u2010Minya Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,11,17]]},"reference":[{"key":"e_1_2_5_2_1","unstructured":"WHO Scientific group Health of elderly TRS NO. 779 WHO General 1989."},{"key":"e_1_2_5_3_1","first-page":"763","volume-title":"Textbook and Atlas of Dermatology","author":"Raja Babu KK","year":"2001"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.87174"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.18941"},{"key":"e_1_2_5_6_1","first-page":"81","volume-title":"Diseases of the Nails and their Management","author":"Baran R","year":"1994"},{"key":"e_1_2_5_7_1","first-page":"2815","volume-title":"Textbook of Dermatology","author":"Dawber RPR","year":"1998"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1983.tb04573.x"},{"key":"e_1_2_5_9_1","first-page":"213","volume-title":"Atlas of Hair and Nails","author":"Cohen PR","year":"2000"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(96)90468-5"},{"issue":"17","key":"e_1_2_5_11_1","first-page":"385","article-title":"Histopathology of the nail","author":"Fleckman P","year":"2001","journal-title":"Adv Dermatol"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2010.07.008"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1955.3"},{"key":"e_1_2_5_14_1","first-page":"173","article-title":"Common nail changes and disorders in older people: diagnosis and management","volume":"57","author":"Abdullah L","year":"2011","journal-title":"Can Family Phys"},{"key":"e_1_2_5_15_1","first-page":"62.1","volume-title":"Rook's Textbook of Dermatology","author":"De Berker DAR","year":"2004"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-011-7846-4"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200910020-00001"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2011.05311.x"},{"key":"e_1_2_5_19_1","first-page":"59","volume-title":"Atlas of Hair and Nails","author":"Holzberg M","year":"2000"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10227-002-0143-0"},{"key":"e_1_2_5_21_1","first-page":"135","volume-title":"Dermatology","author":"Kerkhof PCM","year":"2012"},{"key":"e_1_2_5_22_1","unstructured":"1978 Heinemann London PD Samman The Nails in Disease 1 197"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(92)70242-8"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(93)70100-8"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.7241\/ourd.20123.38"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1980.tb00803.x"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjocd.12113","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjocd.12113","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.12113","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T16:29:59Z","timestamp":1696264199000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.12113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,17]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["10.1111\/jocd.12113"],"URL":"https:\/\/doi.org\/10.1111\/jocd.12113","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,17]]}}}