{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T06:11:14Z","timestamp":1785305474161,"version":"3.55.0"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,3,27]],"date-time":"2015-03-27T00:00:00Z","timestamp":1427414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Xanthelasma Palpebrarum is a type of xanthoma which presents as cosmetic concern.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the efficacy of 30% <jats:styled-content style=\"fixed-case\">TCA<\/jats:styled-content> and Up<jats:styled-content style=\"fixed-case\">CO<\/jats:styled-content><jats:sub>2<\/jats:sub> laser in <jats:styled-content style=\"fixed-case\">XP<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and materials<\/jats:title><jats:p>Fifty patients with <jats:styled-content style=\"fixed-case\">XP<\/jats:styled-content> were categorized clinically into three groups. Patients in each group were alternately allocated to 30% <jats:styled-content style=\"fixed-case\">TCA<\/jats:styled-content> (Group A) and laser (Group B). <jats:styled-content style=\"fixed-case\">TCA<\/jats:styled-content> was applied weekly (maximum: 12 sessions), and laser sessions were given monthly (maximum: three sessions). The primary outcome measures were total patients cured, the number of sessions, and mean <jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content> at the end of treatment. The secondary outcome measures were total duration of treatment, side effects, and recurrence in follow\u2010up (6\u00a0months) (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05 significant).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In Group A, 14 of 25 and in Group B, 25 of 25 patients achieved complete cure (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). The mean <jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content> was lower for Group A (patient: 4.56 <jats:italic>vs<\/jats:italic>. 5.36; physician: 4.64 <jats:italic>vs<\/jats:italic>. 5.44) [<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05] with significant difference only for group <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> patients. Mean number of sessions was less with laser group (1.56 <jats:italic>vs<\/jats:italic>. 9.74), except in group I. There was no significant difference in pigmentary changes and recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>For clinically mild lesions, both <jats:styled-content style=\"fixed-case\">TCA<\/jats:styled-content> and laser are good options, but laser is a better option for severe lesions. Recurrence is a concern with both modalities.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.12137","type":"journal-article","created":{"date-parts":[[2015,3,27]],"date-time":"2015-03-27T22:15:48Z","timestamp":1427494548000},"page":"130-139","source":"Crossref","is-referenced-by-count":23,"title":["A prospective study comparing ultrapulse <scp>CO<\/scp><sub>2<\/sub> laser and trichloroacetic acid in treatment of Xanthelasma palpebrarum"],"prefix":"10.1111","volume":"14","author":[{"given":"Khushbu","family":"Goel","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology Maulana Azad Medical College &amp; Associated Lok Nayak Hospital New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kabir","family":"Sardana","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology Maulana Azad Medical College &amp; Associated Lok Nayak Hospital New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay Kumar","family":"Garg","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology Maulana Azad Medical College &amp; 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