{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T09:29:27Z","timestamp":1788427767594,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,3,23]],"date-time":"2015-03-23T00:00:00Z","timestamp":1427068800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The 1550\u00a0nm Er:Glass fractional laser is widely used for the treatment of atrophic acne scar. A novel fractional radiofrequency microneedle device has recently emerged as an alternative for treating acne scars.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the clinical efficacy and safety of a Er:Glass fractional laser and fractional radiofrequency microneedle device in the treatment of facial atrophic acne scars and to assess the difference between the treatment modalities depending on facial compartment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 40 patients were equally randomized into two groups. Each group of 20 patients received three treatments at 4\u2010week interval using Er:Glass fractional laser or fractional radiofrequency microneedle device.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Scar severity scores (<jats:styled-content style=\"fixed-case\">ECCA<\/jats:styled-content> grading scale) improved by a mean of 25.0% and 18.6% in groups A and B, respectively (both <jats:italic>P\u00a0&lt;\u00a0<\/jats:italic>0.01). The difference in the degree of improvement was not statistically significant between the groups after three sessions of treatment. There were no significant side effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Atrophic acne scars improved in both groups without significant side effects. Additionally, the fractional laser was a more effective treatment option for acne scars, but the fractional radiofrequency microneedle device offered good adherence and short downtime.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.12139","type":"journal-article","created":{"date-parts":[[2015,3,24]],"date-time":"2015-03-24T18:32:59Z","timestamp":1427221979000},"page":"100-106","source":"Crossref","is-referenced-by-count":71,"title":["Comparative study on efficacy and safety of 1550\u00a0nm Er:Glass fractional laser and fractional radiofrequency microneedle device for facial atrophic acne scar"],"prefix":"10.1111","volume":"14","author":[{"given":"Woong Suk","family":"Chae","sequence":"first","affiliation":[{"name":"Department of Dermatology Ulsan University Hospital Ulsan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun Young","family":"Seong","sequence":"additional","affiliation":[{"name":"Department of Dermatology Ulsan University Hospital Ulsan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ha Na","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Dermatology Ulsan University Hospital Ulsan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sook Hyun","family":"Kong","sequence":"additional","affiliation":[{"name":"Department of Dermatology Ulsan University Hospital Ulsan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Ho","family":"Kim","sequence":"additional","affiliation":[{"name":"Biomedical Research Center Ulsan University Hospital Ulsan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ho Seok","family":"Suh","sequence":"additional","affiliation":[{"name":"Department of Dermatology Ulsan University Hospital Ulsan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu Sung","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Ulsan University Hospital Ulsan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,3,23]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sder.2005.03.004"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.01.019"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200001010-00001"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.113451"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.01.003"},{"key":"e_1_2_5_7_1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0151-9638(09)72539-6","article-title":"Ablative and fractional lasers","volume":"136","author":"Beylot C","year":"2009","journal-title":"Ann Dermatol 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