{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T11:05:09Z","timestamp":1791889509964,"version":"4.3.4"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,7,23]],"date-time":"2015-07-23T00:00:00Z","timestamp":1437609600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Platelet\u2010rich plasma (<jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content>) is a highly concentrated autologous solution of plasma prepared from a patient's own blood. <jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content> contains platelets that are purported to release numerous growth factors that may be valuable in numerous dermatologic applications. Here, we review systematically the clinical cosmetic applications of <jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content> including: androgenetic alopecia, scar revision, acne scars, skin rejuvenation, dermal augmentation, and striae distensae to understand the potential and best practices for <jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content> use. A systematic search was conducted on three databases: Pubmed, Embase, and Web of Science. Publications were included if they were in English, investigated the clinical applications of <jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content> in aesthetic dermatology and reported clinical results either as case reports or clinical studies. There were a total of 22 manuscripts that fulfilled these criteria. Four evaluated hair\u2010related applications, eight evaluated the treatment of scars and postprocedure recovery, eight evaluated skin rejuvenation and dermal augmentation, and two evaluated treatment of striae distensae. <jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content> is a relatively new treatment modality with studies suggesting its utility in aesthetic dermatology. The combination of <jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content> with other therapies is particularly interesting. Future studies should include controls, including incorporation of split\u2010face comparisons, to reduce intersubject variability.<\/jats:p>","DOI":"10.1111\/jocd.12167","type":"journal-article","created":{"date-parts":[[2015,7,24]],"date-time":"2015-07-24T05:17:35Z","timestamp":1437715055000},"page":"315-323","source":"Crossref","is-referenced-by-count":149,"title":["Systematic review of the use of platelet\u2010rich plasma in aesthetic dermatology"],"prefix":"10.1111","volume":"14","author":[{"given":"Michael S","family":"Leo","sequence":"first","affiliation":[{"name":"School of Medicine and Public Health University of Wisconsin\u2010Madison Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alur S","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Dermatology Owaisi Hospital and Research Centre Hyderabad 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