{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T07:50:29Z","timestamp":1786693829188,"version":"build-2736575974"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,8,24]],"date-time":"2016-08-24T00:00:00Z","timestamp":1471996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Follicular Unit Extraction (<jats:styled-content style=\"fixed-case\">FUE<\/jats:styled-content>) is considered to be a minimally invasive procedure, and the injury to the donor area caused by a sharp punch may result in dermal fibrosis and clinically observed hypopigmentation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate with advanced image processing the efficacy of using 0.9% normal saline in minimizing the injury to the donor area in <jats:styled-content style=\"fixed-case\">FUE<\/jats:styled-content> donor harvesting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and methods<\/jats:title><jats:p>The term acute extraction (<jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content>) is used to describe the donor harvesting technique, whereby a follicular unit (<jats:styled-content style=\"fixed-case\">FU<\/jats:styled-content>) is removed with a punch that is aligned parallel with the exit angle of the hair follicle. The term vertical extraction (<jats:styled-content style=\"fixed-case\">VE<\/jats:styled-content>) describes the technique where a <jats:styled-content style=\"fixed-case\">FU<\/jats:styled-content> is removed in like manner, but normal saline is injected intradermally prior to harvesting so the punch being perpendicular to the skin. Thirty\u2010five patients were selected for this study to apply both harvesting techniques and then to compare the differences in wound surface size and skin mass removed by the punch.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A significant reduction in the mean values of wound surface and skin mass was recorded in vertical extraction compared to those in acute extraction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The injection of normal saline prior to harvesting proved to be very efficient in minimizing skin injury in <jats:styled-content style=\"fixed-case\">FUE<\/jats:styled-content> harvesting.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.12267","type":"journal-article","created":{"date-parts":[[2016,8,25]],"date-time":"2016-08-25T03:33:11Z","timestamp":1472095991000},"page":"61-69","source":"Crossref","is-referenced-by-count":15,"title":["Minimizing injury to the donor area in follicular unit extraction (<scp>FUE<\/scp>) harvesting"],"prefix":"10.1111","volume":"16","author":[{"given":"Georgios","family":"Zontos","sequence":"first","affiliation":[{"name":"Haarklinikken Copenhagen Denmark"},{"name":"Department of Medical Physics School of Medicine University of Patras Patras Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Ken L.","family":"Williams","sequence":"additional","affiliation":[{"name":"Family Medicine Western University of Health Science Pomona CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Nikiforidis","sequence":"additional","affiliation":[{"name":"Department of Medical Physics School of Medicine University of Patras Patras Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,8,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2002.01320.x"},{"key":"e_1_2_7_3_1","first-page":"133","volume-title":"Hair Transplantation","author":"Rassman W","year":"2006"},{"key":"e_1_2_7_4_1","first-page":"798","article-title":"Current practices and controversies in cosmetic hair restoration","volume":"39","author":"Ken L","year":"2013","journal-title":"Dermatol Surg"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2009.01283.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp\/books\/12687_17"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsc.2013.05.009"},{"key":"e_1_2_7_8_1","unstructured":"RoseP.Internal Angle of Hair Growth versus Exit Angle as it relates to FIT\/FUE Presented International Society Of Hair Restoration Surgery Annual Meeting 2010 Boston MA.7"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/1524-4725.2006.32006"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.DSS.0000452652.52507.9d"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp\/books\/12687_5"},{"key":"e_1_2_7_12_1","unstructured":"ZabelD.Wound healing. 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