{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T09:32:53Z","timestamp":1788427973409,"version":"build-2803163510"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,10,26]],"date-time":"2017-10-26T00:00:00Z","timestamp":1508976000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Microneedling with dermaroller and glycolic acid peels is commonly used for treatment of acne scars.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare efficacy of microneedling alone versus combination of microneedling with serial 70% glycolic acid peel in management of atrophic acne scars.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods &amp; Materials<\/jats:title><jats:p>Sixty patients with atrophic acne scars were randomized into group 1 receiving microneedling at 0, 6, and 12 weeks and group 2 receiving microneedling at 0, 6, and 12 weeks along with 70% glycolic acid peel at 3, 9, and 15 weeks. Acne scar scoring was performed by a blinded observer using <jats:styled-content style=\"fixed-case\">ECCA<\/jats:styled-content> (Echelle d'evaluation clinique des cicatrices d'acne) scoring at baseline and after 22 weeks. Additionally, patients were asked to grade the improvement in acne scars and skin texture on visual analogue scale (<jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 60 patients, 52 completed the 22\u2010week study period. The decrement from baseline in mean <jats:styled-content style=\"fixed-case\">ECCA<\/jats:styled-content> score was more in group 2 as compared to group 1 (39.65\u00b12.50 vs 29.58\u00b10.18; <jats:italic>P<\/jats:italic>&lt;.001). Group 2 also showed more improvement in skin texture as compared to group 1 on <jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Addition of sequential 70% glycolic acid peel to microneedling gives better scar improvement as compared to microneedling alone. In addition to this, it also improves skin texture.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.12377","type":"journal-article","created":{"date-parts":[[2017,10,26]],"date-time":"2017-10-26T12:06:41Z","timestamp":1509019601000},"page":"454-459","source":"Crossref","is-referenced-by-count":34,"title":["Efficacy of microneedling with 70% glycolic acid peel vs microneedling alone in treatment of atrophic acne scars\u2014A randomized controlled trial"],"prefix":"10.1111","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6033-7516","authenticated-orcid":false,"given":"Shiwangi","family":"Rana","sequence":"first","affiliation":[{"name":"Department of Dermatology Lady Hardinge Medical College New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vibhu","family":"Mendiratta","sequence":"additional","affiliation":[{"name":"Department of Dermatology Lady Hardinge Medical College New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ram","family":"Chander","sequence":"additional","affiliation":[{"name":"Department of Dermatology Lady Hardinge Medical College New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,10,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1994.tb01200.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.05.029"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2000.00076.x"},{"key":"e_1_2_5_5_1","first-page":"59","article-title":"Glycolic acid peels versus salicylic\u2010mandelic acid peels in active acne vulgaris and post\u2010acne scarring and hyper pigmentation: a comparative study","volume":"35","author":"Garg VK","year":"2009","journal-title":"Dermatol Surg"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1473-2165.2011.00583.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.51244"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1998.02510.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1971.tb07195.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.95450"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-011-9715-y"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1997.18131897.x"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e318188245e"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/893080"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2077.53096"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2009.03291.x"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2010.01854.x"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jccw.2012.11.001"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000304612.72899.02"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2077.129964"},{"issue":"4","key":"e_1_2_5_21_1","article-title":"Combination treatment of skin needling, platelet\u2010rich plasma and glycolic acid 70% chemical peeling for atrophic acne scars in fitzpatrick's skin type IV\u2013VI","volume":"7","author":"Tantari SHW","year":"2016","journal-title":"J Clin Exp Dermatol"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1243082"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjocd.12377","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.12377","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T00:28:53Z","timestamp":1696033733000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.12377"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,26]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["10.1111\/jocd.12377"],"URL":"https:\/\/doi.org\/10.1111\/jocd.12377","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"value":"1473-2130","type":"print"},{"value":"1473-2165","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,26]]}}}