{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T06:57:56Z","timestamp":1763535476410,"version":"3.37.3"},"reference-count":12,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,11,21]],"date-time":"2017-11-21T00:00:00Z","timestamp":1511222400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2018,6]]},"abstract":"Summary<\/jats:title>Objective<\/jats:title>This study was designed to investigate serum homocysteine (HCY<\/jats:styled-content>) levels in acne patients.<\/jats:p><\/jats:sec>Methods<\/jats:title>Acne patients (n = 124) and healthy volunteers (n = 70), matched in terms of both age and sex, were enrolled. Serum HCY<\/jats:styled-content> levels for all subjects were measured by a clinical laboratory.<\/jats:p><\/jats:sec>Results<\/jats:title>Serum HCY<\/jats:styled-content> levels in male and female patients with severe and moderate acne were significantly higher than in the healthy control group (P<\/jats:italic> < .05). The constituent ratio of male and female acne patients with HCY<\/jats:styled-content> above the normal range (10 mmol\/L) was significantly higher than the healthy control group. The severity of acne patients was positively correlated with serum homocysteine concentration, (P<\/jats:italic> < .01).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Hyperhomocysteinemia may be an independent risk factor for acne vulgaris. Detection of serum HCY<\/jats:styled-content> is important for acne patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.12456","type":"journal-article","created":{"date-parts":[[2017,11,21]],"date-time":"2017-11-21T07:26:44Z","timestamp":1511249204000},"page":"523-526","source":"Crossref","is-referenced-by-count":7,"title":["Serum homocysteine levels in acne patients"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8475-9433","authenticated-orcid":false,"given":"Hao","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of Dermatology Clinical Research Center The First Affiliated Hospital of Guangxi University of Chinese Medicine Nanning China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changyi","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Dermatology Clinical Research Center The First Affiliated Hospital of Guangxi University of Chinese Medicine Nanning China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Wei","sequence":"additional","affiliation":[{"name":"Clinical Research Center Ruikang Hospital Guangxi University of Chinese Medicine Nanning China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Wang","sequence":"additional","affiliation":[{"name":"Clinical Research Center Ruikang Hospital Guangxi University of Chinese Medicine Nanning China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiang","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Dermatology Clinical Research Center The First Affiliated Hospital of Guangxi University of Chinese Medicine Nanning China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianqi","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Clinical Research Center The First Affiliated Hospital of Guangxi University of Chinese Medicine Nanning China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,11,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-011-0430-0"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa060900"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2007.00403.x-i1"},{"key":"e_1_2_7_5_1","first-page":"579","article-title":"2010 Chinese guidelines for the management of hypertension","volume":"39","author":"Liu LS","year":"2012","journal-title":"Am J Hypertens"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2007.1750"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2000-8096"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1024\/0301-1526.33.4.191"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2013.11.005"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/136.3.750S"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2891-14-6"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-8981(02)00174-2"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2014.00343"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjocd.12456","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.12456","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T17:30:20Z","timestamp":1695490220000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.12456"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,21]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1111\/jocd.12456"],"URL":"https:\/\/doi.org\/10.1111\/jocd.12456","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"type":"print","value":"1473-2130"},{"type":"electronic","value":"1473-2165"}],"subject":[],"published":{"date-parts":[[2017,11,21]]}}}