{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:56:55Z","timestamp":1790812615148,"version":"4.1.0"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,11,21]],"date-time":"2017-11-21T00:00:00Z","timestamp":1511222400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"ColoreScience Inc.","award":["$3000"],"award-info":[{"award-number":["$3000"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The visible signs of photodamage can be improved by intense pulsed light (<jats:styled-content style=\"fixed-case\">IPL<\/jats:styled-content>). Active ingredients in cosmeceuticals also have effects on skin quality and pigmentation, and can camouflage post\u2010treatment side effects. Combination therapies utilizing different treatment modalities have been shown to optimize clinical outcomes for skin rejuvenation and patient satisfaction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the efficacy of a combination of <jats:styled-content style=\"fixed-case\">IPL<\/jats:styled-content> with a daily topical skincare and sunscreen regimen for the treatment of facial photodamage and for the improvement of <jats:styled-content style=\"fixed-case\">IPL<\/jats:styled-content> treatment tolerability.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients\/Methods<\/jats:title><jats:p>Twenty female subjects with moderate\u2010to\u2010severe facial photodamage, with past history of <jats:styled-content style=\"fixed-case\">IPL<\/jats:styled-content> treatments, received one <jats:styled-content style=\"fixed-case\">IPL<\/jats:styled-content> treatment followed by the use of the topical skincare regimen for 8\u00a0weeks. An investigator assessed facial photodamage and hyperpigmentation at baseline, week 4, and week 8, and postprocedure erythema. Subject questionnaires were also administered at each visit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared to baseline, there was a significant improvement in photodamage and hyperpigmentation of bare facial skin. The application of the skincare regimen resulted in a significant reduction in post\u2010<jats:styled-content style=\"fixed-case\">IPL<\/jats:styled-content> erythema, stinging\/burning, and itching. The majority of patients were very satisfied or satisfied and felt the treatment regimen improved various aspects of skin quality and the tolerability of the procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The addition of a topical skincare regimen after <jats:styled-content style=\"fixed-case\">IPL<\/jats:styled-content> treatment to the face resulted in significant improvements in facial photodamage and pigmentation, decreased post\u2010treatment side effects, and increased tolerability.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.12463","type":"journal-article","created":{"date-parts":[[2017,11,22]],"date-time":"2017-11-22T04:25:15Z","timestamp":1511324715000},"page":"441-447","source":"Crossref","is-referenced-by-count":9,"title":["Open\u2010label study assessing the efficacy and tolerability of topical skincare and sun protection products following intense pulsed light treatment"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3383-5798","authenticated-orcid":false,"given":"Isabela T","family":"Jones","sequence":"first","affiliation":[{"name":"McLean Dermatology and Skincare Center McLean VA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Guiha","sequence":"additional","affiliation":[{"name":"Goldman, Butterwick, Groff, Fabi &amp; Wu Cosmetic Laser Dermatology \u2010 A West Dermatology Company San Diego CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina G","family":"Fabi","sequence":"additional","affiliation":[{"name":"Goldman, Butterwick, Groff, Fabi &amp; Wu Cosmetic Laser Dermatology \u2010 A West Dermatology Company San Diego CA USA"},{"name":"University of California San Diego CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,11,21]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"GustavssonM.American medical bio care.1989. 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