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The safety and efficacy of repeated intradermal injections of <jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content> has proved to promote hair growth in a number of randomized clinical trials. Biologically active proteins and cytokines released upon platelet activation have shown to induce folliculogenesis and activate the anagen growing phase of dormant bulbs. Interestingly, further studies have revealed that combining <jats:styled-content style=\"fixed-case\">PRP<\/jats:styled-content> with other hair loss\u2010related products may enhance the final performance of the treatment. These synergistic approaches include Food and Drug Administration (<jats:styled-content style=\"fixed-case\">FDA<\/jats:styled-content>) approved drugs such as finasteride or minoxidil, bioactive macromolecules and cell\u2010based therapies. Here, recent research involving alone or combined therapy with platelet\u2010rich plasma for the management of hair loss\u2010related disorders are outlined and future prospects are discussed.<\/jats:p>","DOI":"10.1111\/jocd.12683","type":"journal-article","created":{"date-parts":[[2018,6,15]],"date-time":"2018-06-15T00:57:24Z","timestamp":1529024244000},"page":"483-486","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Platelet rich plasma for the management of hair loss: Better alone or in combination?"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8386-5303","authenticated-orcid":false,"given":"Eduardo","family":"Anitua","sequence":"first","affiliation":[{"name":"BTI Biotechnology Institute Vitoria Spain"},{"name":"Eduardo Anitua Foundation Vitoria Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3926-4989","authenticated-orcid":false,"given":"Ander","family":"Pino","sequence":"additional","affiliation":[{"name":"BTI Biotechnology Institute Vitoria Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Ja\u00e9n","sequence":"additional","affiliation":[{"name":"Hospital Ram\u00f3n y Cajal Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00aa Rogelia","family":"Navarro","sequence":"additional","affiliation":[{"name":"Centro Dermatol\u00f3gico Est\u00e9tico Alicante Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,6,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0022-202X.2004.23237.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbcan.2010.04.001"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1160\/TH03-07-0440"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2011.110505"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-016-0196-2"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.5966\/sctm.2015-0107"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12397"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2016.1179712"},{"key":"e_1_2_6_10_1","first-page":"529","article-title":"Plasma rich in growth factors: preliminary results of use in the preparation of future sites for implants","volume":"14","author":"Anitua E","year":"1999","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.progpolymsci.2014.01.001"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2009.00159.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2009.00233.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2006.10.044"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e31825a6d9a"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546515620383"},{"key":"e_1_2_6_17_1","doi-asserted-by":"crossref","first-page":"69","DOI":"10.46582\/jsrm.1202011","article-title":"Randomized controlled trial comparing hyaluronic acid, platelet\u2010rich plasma and the combination of both in the treatment of mild and moderate osteoarthritis of the knee","volume":"12","author":"Lana JF","year":"2016","journal-title":"J Stem Cells Regen Med"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0157048"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/1099800414535840"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2011.02123.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12250"},{"key":"e_1_2_6_22_1","doi-asserted-by":"crossref","unstructured":"AlvesR GrimaltR.Platelet\u2010rich plasma in combination with 5% minoxidil topical solution and 1\u00a0mg oral finasteride for the treatment of androgenetic alopecia: a randomized placebo controlled double\u2010blind half\u2010head study. 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