{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T16:37:33Z","timestamp":1787589453784,"version":"build-2736575974"},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,10,2]],"date-time":"2018-10-02T00:00:00Z","timestamp":1538438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Melasma is a common acquired facial pigmentary disorder that is resistant to various modalities of treatment. Recently, the low\u2010fluence 1064\u2010nm Q\u2010switched neodymium\u2010doped yttrium aluminum garnet laser (QSNY) has emerged as the new gold standard of melasma treatment in Asia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the efficacy and safety of low\u2010fluence 1064\u2010nm QSNY in Asian patients with melasma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Data of patients with melasma treated with low\u2010fluence QSNY in the department of dermatology at the Korea University Anam Hospital were reviewed retrospectively. A 1064\u2010nm QSNY with 8\u00a0mm spot size and fluence of 1.2\u20102.0\u00a0J\/cm\n                      <jats:sup>2<\/jats:sup>\n                      at 10\u00a0Hz was used. The results were evaluated using the modified Melasma Area and Severity Index (mMASI) score and the physician's global assessment (PGA).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 40 Korean patients with Fitzpatrick skin type III to IV were included. Patients were treated for a median of 10 sessions at a median of 1\u2010week intervals. The mean mMASI score decreased by 54.23% from a baseline of 3.19\u00a0\u00b1\u00a02.64 to 1.46\u00a0\u00b1\u00a01.06 after treatment. On PGA, 1 out of 40 patients (2.5%) showed excellent improvement, 14 (35%) good, 15 (37.5%) fair, 6 (15%) poor, and 4 (10%) no improvement. However, two patients showed mottled hypopigmentation and rebound hyperpigmentation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Low\u2010fluence 1064\u2010nm QSNY appears to be a safe and effective treatment for Asian patients with melasma.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.12760","type":"journal-article","created":{"date-parts":[[2018,10,2]],"date-time":"2018-10-02T20:49:47Z","timestamp":1538513387000},"page":"1053-1058","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Low\u2010fluence Q\u2010switched Nd:YAG laser for the treatment of melasma in Asian patients"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1215-7078","authenticated-orcid":false,"given":"Jae Eun","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Dermatology, College of Medicine Korea University Seoul"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Won","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology, College of Medicine Korea University Seoul"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soo Hong","family":"Seo","sequence":"additional","affiliation":[{"name":"Department of Dermatology, College of Medicine Korea University Seoul"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyo Hyun","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Dermatology, College of Medicine Korea University Seoul"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Chul","family":"Kye","sequence":"additional","affiliation":[{"name":"Department of Dermatology, College of Medicine Korea University 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