{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:24:41Z","timestamp":1790699081337,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,9,17]],"date-time":"2018-09-17T00:00:00Z","timestamp":1537142400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although a 1450\u2010nm diode laser has been shown to be effective for acne, the conventional high\u2010energy stamp\u2010only regimen is often associated with pain and hyperpigmentation, especially for dark\u2010skinned individuals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To evaluate whether the novel dual regimen has clinical advantages for acne treatments compared with conventional regimen in Asian patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>Twenty\u2010four Korean patients with facial acne were treated with a 1450\u2010nm diode laser through a 20\u2010week, randomized, split\u2010face study. The patients were treated with three consecutive sessions at 4\u2010week intervals. One half of the face received a dual regimen consisting of low\u2010fluence stamping mode (5\u20106\u00a0J\/cm<jats:sup>2<\/jats:sup>) for inflammatory acne lesions only, followed by 4\u20105 passes of moving mode for the full face. The other side received a single\u2010pass treatment of conventional high\u2010fluence stamp mode (14\u201015\u00a0J\/cm<jats:sup>2<\/jats:sup>). Evaluations for acne, sebum secretion measurements, and safety profiles were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At the final 12\u2010week follow\u2010up evaluations, the dual\u2010mode side demonstrated better improvements in both inflammatory and noninflammatory lesion counts, acne severity assessments, and reduction in sebum secretion compared with stamp\u2010only side. Subjective satisfaction for the improvement for acne, seborrhea, and texture correlated well with objective assessments. In addition, degrees of pain and treatment\u2010related side effects were remarkably decreased in the novel dual mode.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This novel dual regimen of the 1450\u2010nm laser demonstrated improved efficacies for acne and seborrhea with satisfactory safety profiles. Therefore, this regimen would be a viable option for acne treatments either as monotherapy or as combination therapy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.12788","type":"journal-article","created":{"date-parts":[[2018,9,18]],"date-time":"2018-09-18T01:00:36Z","timestamp":1537232436000},"page":"1063-1068","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Comparison of novel dual mode vs conventional single pass of a 1450\u2010nm diode laser in the treatment of acne vulgaris for Korean patients: A 20\u2010week prospective, randomized, split\u2010face study"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8194-1790","authenticated-orcid":false,"given":"Hyuck Hoon","family":"Kwon","sequence":"first","affiliation":[{"name":"Oaro Dermatology Clinic Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun Chul","family":"Choi","sequence":"additional","affiliation":[{"name":"Oaro Dermatology Clinic Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Yoon","family":"Jung","sequence":"additional","affiliation":[{"name":"Oaro Dermatology Clinic Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"You In","family":"Bae","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Dongtan Sacred Heart Hospital Hallym University College of Medicine  Hwaseong Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gyeong\u2010Hun","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Dongtan Sacred Heart Hospital Hallym University College of Medicine  Hwaseong 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