{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T04:21:25Z","timestamp":1783570885727,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,10,29]],"date-time":"2018-10-29T00:00:00Z","timestamp":1540771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Acral vitiligo is a resistant subtype of vitiligo that does not respond easily to any treatment modality. Ultraviolet A1 (UVA1) (340\u2010400\u00a0nm) therapy can penetrate the deep dermis of the skin and is relatively free of adverse effects associated with different phototherapeutic modalities. This study's objective was to evaluate the effect of medium\u2010dose long\u2010wavelength UVA1 (40\u201070\u00a0J) in acral vitiligo treatment and compare it with topical psoralen plus ultraviolet A (topical PUVA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients in this randomized\u2010controlled comparative clinical trial were divided into two groups, medium\u2010dose UVA1 group and topical PUVA group (10 acral vitiligo patients each). Patients received 36 sessions of phototherapy over a period of 12\u00a0weeks. Every patient was clinically evaluated monthly as regards the appearance of new lesions or increase in diameter of the current lesion according to point counting and vitiligo area severity index.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      No statistically significant clinical difference was found between patients in UVA1 and topical PUVA groups regarding response and pattern of response (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&gt;\u00a00.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Ultraviolet A1 seems to be of limited use as a monotherapy in acral vitiligo treatment. However, more studies combining it with other treatment modalities as systemic steroids and\/or using higher UVA1 doses may prove beneficial.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jocd.12808","type":"journal-article","created":{"date-parts":[[2018,10,30]],"date-time":"2018-10-30T06:12:32Z","timestamp":1540879952000},"page":"1155-1160","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["The role of long\u2010wavelength ultraviolet A1 (UVA1) in acral vitiligo"],"prefix":"10.1111","volume":"18","author":[{"given":"Bakr Mohamed","family":"El\u2010Zawahry","sequence":"first","affiliation":[{"name":"Dermatology Department, Faculty of Medicine Cairo University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3873-3897","authenticated-orcid":false,"given":"Maha Fathy","family":"Elmasry","sequence":"additional","affiliation":[{"name":"Dermatology Department, Faculty of Medicine Cairo University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amira","family":"Ragab","sequence":"additional","affiliation":[{"name":"Dermatology Department, El Haud El Marsoud Hospital Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,10,29]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.07.053"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2006.00222.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2007.04.008"},{"key":"e_1_2_7_5_1","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1111\/j.1468-3083.2006.02035.x","article-title":"Comparison of systemic PUVA and NB\u2010UVB in the treatment of vitiligo: an open prospective study","volume":"21","author":"Bhatnagar A","year":"2007","journal-title":"J Eur Acad Dermatol 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