{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T16:35:34Z","timestamp":1756571734852,"version":"3.40.5"},"reference-count":9,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,1,3]],"date-time":"2019-01-03T00:00:00Z","timestamp":1546473600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Barraquer\u2010Simons syndrome (BSS) or acquired partial lipodystrophy is a disorder of loss of subcutaneous fat from the upper part of the body. The resulting cosmetic disfigurement causes significant psychological distress in the affected individuals. Fillers, autologous fat transplant or cosmetic surgeries can be used to correct the volume deficit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The authors report a case of a young woman, who presented with gradual loss of subcutaneous fat from the face, upper limbs, and trunk. On evaluation, she had low complement C3 levels, but there were no features to suggest any metabolic complication. She was diagnosed with BSS. Her volume deficit in the midface area was managed with hyaluronic acid (HA) filler.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The treatment has resulted in the correction of her facial volume loss immediately following the procedure with a maintained effect at follow\u2010up visits. She experienced no major adverse events.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Hyaluronic acid filler is safe and effective for the management of volume loss in BSS. It gives a long lasting result and an added self\u2010confidence to the patient.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.12847","type":"journal-article","created":{"date-parts":[[2019,1,3]],"date-time":"2019-01-03T08:30:53Z","timestamp":1546504253000},"page":"1264-1266","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Hyaluronic acid fillers for correcting midface volume deficit in Barraquer\u2010Simons syndrome"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9024-6842","authenticated-orcid":false,"given":"T. P.","family":"Afra","sequence":"first","affiliation":[{"name":"Dermatology, Venereology and Leprology Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6323-4988","authenticated-orcid":false,"given":"Keshavamurthy","family":"Vinay","sequence":"additional","affiliation":[{"name":"Dermatology, Venereology and Leprology Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammed","family":"Razmi T","sequence":"additional","affiliation":[{"name":"Dermatology, Venereology and Leprology Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tarun","family":"Narang","sequence":"additional","affiliation":[{"name":"Dermatology, Venereology and Leprology Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunil","family":"Dogra","sequence":"additional","affiliation":[{"name":"Dermatology, Venereology and Leprology Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,1,3]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(99)00414-3"},{"key":"e_1_2_4_3_1","first-page":"43","article-title":"Systemic lupus erythematosus, partial lipodystrophy and hypocomplementemia","volume":"6","author":"Jasin HE","year":"1979","journal-title":"J Rheumatol"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-016-1975-9"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecl.2016.06.012"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2016.3827"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000000416"},{"key":"e_1_2_4_8_1","article-title":"Barraquer\u2010Simons syndrome: a unique patient's perspective on diagnosis, disease progression and recontouring treatment","volume":"2016","author":"Heidemann LN","year":"2016","journal-title":"BMJ Case Rep"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cps.2011.03.011"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2018.0516"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjocd.12847","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.12847","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.12847","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.12847","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T17:38:05Z","timestamp":1694021885000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.12847"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,3]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1111\/jocd.12847"],"URL":"https:\/\/doi.org\/10.1111\/jocd.12847","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"type":"print","value":"1473-2130"},{"type":"electronic","value":"1473-2165"}],"subject":[],"published":{"date-parts":[[2019,1,3]]},"assertion":[{"value":"2018-11-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}