{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T15:27:03Z","timestamp":1758814023949,"version":"3.40.5"},"reference-count":7,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,1,20]],"date-time":"2019-01-20T00:00:00Z","timestamp":1547942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Periorbital pigmentation is a commonly encountered condition which presents clinically as bilateral round, oval or semicircular homogenous dark brown pigmented macules in the periocular region. It may influence quality of life of an individual with its strong psychological impact. We present a case of middle\u2010aged female patient, who had periorbital pigmentation as a manifestation of acanthosis nigricans. On evaluation, she was found to have hypertension, hyperglycemia, and dyslipidemia and she fulfilled the criteria for metabolic syndrome. We believe, it is important to evaluate the patients who present as periorbital pigmentation with clinical features of acanthosis nigricans for underlying metabolic syndrome.<\/jats:p>","DOI":"10.1111\/jocd.12852","type":"journal-article","created":{"date-parts":[[2019,1,20]],"date-time":"2019-01-20T18:45:56Z","timestamp":1548009956000},"page":"1584-1586","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Periorbital pigmentation: An alarming sign of metabolic syndrome"],"prefix":"10.1111","volume":"18","author":[{"given":"Vijay","family":"Zawar","sequence":"first","affiliation":[{"name":"Skin Diseases Center  Nashik India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7600-1454","authenticated-orcid":false,"given":"Snehal","family":"Daga","sequence":"additional","affiliation":[{"name":"Department of Dermatology Dr. Vasantrao Pawar Medical College, Hospital &amp; Research Centre  Nashik India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manoj","family":"Pawar","sequence":"additional","affiliation":[{"name":"Skin Diseases Center  Nashik India"},{"name":"Department of Dermatology Dr. Vasantrao Pawar Medical College, Hospital &amp; Research Centre  Nashik India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shrikant","family":"Kumavat","sequence":"additional","affiliation":[{"name":"Skin Diseases Center  Nashik India"},{"name":"Department of Dermatology Dr. Vasantrao Pawar Medical College, Hospital &amp; Research Centre  Nashik India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,1,20]]},"reference":[{"key":"e_1_2_2_2_1","first-page":"49","article-title":"Periorbital hyperpigmentation: a comprehensive review","volume":"9","author":"Sarkar R","year":"2016","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/2229-5178.193898"},{"key":"e_1_2_2_4_1","first-page":"591","article-title":"Facial acanthosis nigricans: a morphological marker of metabolic syndrome","volume":"62","author":"Panda S","year":"2017","journal-title":"Indian J Dermatol"},{"key":"e_1_2_2_5_1","first-page":"84","article-title":"Acanthosis Nigricans as a Cause of facial melanosis (Clinical And histopathological Study) IOSR","volume":"1","author":"Sharquie KE","year":"2015","journal-title":"J Dent Med Sci"},{"key":"e_1_2_2_6_1","first-page":"163","article-title":"Consensus statement for diagnosis of obesity, abdominal obesity and the metabolic syndrome for Asian Indians and recommendations for physical activity, medical and surgical management","volume":"57","author":"Misra A","year":"2009","journal-title":"J Assoc Physicians India"},{"key":"e_1_2_2_7_1","doi-asserted-by":"crossref","first-page":"e0192372","DOI":"10.1371\/journal.pone.0192372","article-title":"Prevalence of metabolic syndromeand its risk factors in Kerala, South India: Analysis of a community basedcross\u2010sectional study","volume":"13","author":"Harikrishnan S","year":"2019","journal-title":"PLoS ONE"},{"key":"e_1_2_2_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/2229-5178.137765"}],"container-title":["Journal of Cosmetic Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjocd.12852","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.12852","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jocd.12852","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jocd.12852","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T17:41:32Z","timestamp":1694022092000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jocd.12852"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,20]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1111\/jocd.12852"],"URL":"https:\/\/doi.org\/10.1111\/jocd.12852","archive":["Portico"],"relation":{},"ISSN":["1473-2130","1473-2165"],"issn-type":[{"type":"print","value":"1473-2130"},{"type":"electronic","value":"1473-2165"}],"subject":[],"published":{"date-parts":[[2019,1,20]]},"assertion":[{"value":"2018-04-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}