{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T03:06:08Z","timestamp":1787972768497,"version":"build-2784847793"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,1,20]],"date-time":"2019-01-20T00:00:00Z","timestamp":1547942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Lichen Planus Pigmentosus (LPP), a disorder with stubborn treatment\u2010refractory hyperpigmentation predominantly affects the darker skin. Deep dermal pigmentary incontinence of LPP renders the condition treatment\u2010refractory.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Lack of a consistently effective depigmenting treatment protocol of inactive LPP mandates exploration of novel approaches. We analyzed the effect of six sessions of modified phenol peel on reduction of pigmentation of LPP in Indian patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The results of a retrospective analysis of the efficacy and safety of six sessions of Croton oil free phenol combination (CFPC) peel done every 3\u00a0weeks, for inactive LPP\u2010associated hyperpigmentation in 17 patients are presented. Efficacy evaluation was done with patient\u2010reported improvement, physician\u2010evaluated improvement (photographic comparison of baseline and post\u2010treatment clinical images), and pre\u2010 and posttreatment comparison of dermoscopic images using a simple scale.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Out of 17, 5 (29%) patients sustained excellent improvement with &gt;75% reduction of pigmentation. Overall 13 (76%) patients had moderate to excellent improvement, that is, at least 25% or more reduction in pigmentation. The patient\u2010reported improvement, physician\u2010graded improvement, and dermoscopic changes\u2014all three measures showed harmonious overlap. Lightening of the background color and reduction in density and color intensity of pigmented structures was observed on dermoscopy in majority of patients. The treatment was well tolerated with no serious local\/systemic adverse effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Modified phenol peels seem effective in reduction of hyperpigmentation of LPP. They are safe and well tolerated. Thorough priming, stringent sun protection and use of post\u2010peel adjuvant topicals boost the peel effect and aid in maintaining the effect for up to a year.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.12862","type":"journal-article","created":{"date-parts":[[2019,1,20]],"date-time":"2019-01-20T18:45:40Z","timestamp":1548009940000},"page":"1479-1486","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Modified phenol peels for treatment\u2010refractory hyperpigmentation of lichen planus pigmentosus: A retrospective clinico\u2010dermoscopic analysis"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7444-4956","authenticated-orcid":false,"given":"Sidharth","family":"Sonthalia","sequence":"first","affiliation":[{"name":"Department of Dermatology &amp; Dermatosurgery Skinnocence: The Skin Clinic &amp; Research Center  Gurugram India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maya","family":"Vedamurthy","sequence":"additional","affiliation":[{"name":"Department of Dermatology &amp; Dermatosurgery RSV Skin &amp; Laser Center  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Dermatology Poornima Hospital  Bengaluru India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamad","family":"Goldust","sequence":"additional","affiliation":[{"name":"Department of Dermatology Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6010-3771","authenticated-orcid":false,"given":"Abhijeet K.","family":"Jha","sequence":"additional","affiliation":[{"name":"Department of Dermatology &amp; STD PMCH  Patna 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