{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:13:10Z","timestamp":1787015590840,"version":"build-2736575974"},"reference-count":44,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,4,13]],"date-time":"2019-04-13T00:00:00Z","timestamp":1555113600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    The second most common alopecia\u2014Androgenetic alopecia (AGA)\u2014occurs due to hormonal imbalance. Dihydrotestosterone (DHT) an androgenic hormone is a sex steroid, produced in the gonads. The target sites of DHT are similar to that of testosterone, and it attaches easily remaining bound for 53\u00a0minutes as compared to 35\u00a0minutes of testosterone. Excess of DHT causes miniaturization of hair reducing the anagen phase and increasing the telogen phase leading to hair loss. Normally up to ten percent of testosterone in the body irreversibly gets converted into DHT by the action of enzyme 5\u2010alpha\u2010reductase. Inadequate blood flow to the scalp can also be another reason for hair loss encountered due to lower oxygen and nutrients reaching it. AGA affects both sexes; however in males, it leads to major hair loss. Conventional drugs such as minoxidil and finasteride are widely used for the treatment. However, several drawbacks such as allergic contact dermatitis, burning, ejaculation disorder, and decreased libido are reported. Available literature suggests the role of herbal drugs to have the action against 5\u2010alpha\u2010reductase enzyme inhibiting it and reducing the hair loss. This can be further potentiated since they exhibit lesser side effects. Recent advancements observed in the medicinal, cosmetic, and engineering fields can prove to be an asset. This article focuses on herbs which can be used in AGA. A review of Saw palmetto (\n                    <jats:italic>Serenoa repens<\/jats:italic>\n                    ), Green tea (\n                    <jats:italic>Camellia sinensis<\/jats:italic>\n                    ), Pumpkin seed (\n                    <jats:italic>Curcurbita pepo<\/jats:italic>\n                    ), Rosemary (\n                    <jats:italic>Rosmarinus officinalis<\/jats:italic>\n                    ), Grape seed (\n                    <jats:italic>Vitis vinifera<\/jats:italic>\n                    ), and Licorice (\n                    <jats:italic>Glycyrrhiza glabra<\/jats:italic>\n                    ) is attempted.\n                  <\/jats:p>","DOI":"10.1111\/jocd.12930","type":"journal-article","created":{"date-parts":[[2019,4,13]],"date-time":"2019-04-13T06:23:56Z","timestamp":1555136636000},"page":"966-975","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":101,"title":["An overview of herbal alternatives in androgenetic alopecia"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0788-3841","authenticated-orcid":false,"given":"Maria Yusuf","family":"Dhariwala","sequence":"first","affiliation":[{"name":"Dr. Bhanuben Nanavati College of Pharmacy Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Padmini","family":"Ravikumar","sequence":"additional","affiliation":[{"name":"Dr. Bhanuben Nanavati College of Pharmacy Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,4,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-014-0077-5"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-016-0629-5"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000248896"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.116730"},{"key":"e_1_2_6_6_1","first-page":"179","article-title":"Androgenetic alopecia \u2010 current status","volume":"50","author":"Thomas J","year":"2005","journal-title":"Indian J Dermatol"},{"key":"e_1_2_6_7_1","first-page":"35","article-title":"Current therapies of female androgenetic alopecia and use of fluridil, a novel topical antiandrogen","volume":"79","author":"R. 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