{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T12:25:33Z","timestamp":1783772733643,"version":"3.55.0"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,4,24]],"date-time":"2019-04-24T00:00:00Z","timestamp":1556064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Cosmetic Dermatology"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Intense pulsed light therapy (IPL) decreases facial erythema and telangiectasias associated with rosacea. Topical skin care products decrease facial erythema by the action of active ingredients and masking effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess the efficacy and tolerability of combining a topical skin care regimen (TSCR) comprised of a multifunctional three\u2010in\u2010one facial cream and a mineral\u2010based brush\u2010on SPF50 powder sunscreen with a single IPL treatment for treating mild\u2010to\u2010severe facial redness associated with rosacea.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty female subjects with Fitzpatrick skin types I\u2010III received TSCR monotherapy for 12\u00a0weeks. At that time, subjects received a single IPL treatment and continued TSCR for 6 additional weeks. Subjects were evaluated at Baseline and at Weeks 4, 8, 12, and 18.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Using a 7\u2010point redness scale, the overall mean (SD) redness score significantly improved from 3.05 (0.97) at baseline to 2.05 (0.76) at Week 18 (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.01). There was a decrease in investigator\u2010rated erythema from baseline (bare skin) to Week 12 (bare skin, before IPL) when TSCR was used as monotherapy which did not achieve significance (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.12). Most subjects (80%) were satisfied or Very satisfied with the TSCR at Week 18. All subjects (100%) agreed that it improved their baseline skin redness and most (85%) would recommend TSCR to others. TSCR was well\u2010tolerated with no significant changes in skin dryness, scaling, or itching. Mild burning occurred immediately following the IPL treatment at Week 12.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>TSCR in combination with a single IPL treatment produced a significant improvement in overall facial redness in patients with rosacea. Longer\u2010term treatment with TSCR may produce continued improvement.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jocd.12952","type":"journal-article","created":{"date-parts":[[2019,4,24]],"date-time":"2019-04-24T14:22:55Z","timestamp":1556115775000},"page":"1758-1764","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Open\u2010label study assessing the efficacy and tolerability of topical skin care and sun protection alone and in combination with intense pulsed light therapy"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4198-3528","authenticated-orcid":false,"given":"Jennifer","family":"Deaver Peterson","sequence":"first","affiliation":[{"name":"The Pearl Dermatology Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracy M.","family":"Katz","sequence":"additional","affiliation":[{"name":"The Pearl Dermatology Houston 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